A novel cell-penetrating peptide derived from WT1 enhances p53 activity, induces cell senescence and displays antimelanoma activity in xeno- and syngeneic systems

by Mariana H. Massaoka, Alisson L. Matsuo, Carlos R. Figueiredo, Natalia Girola, Camyla F. Faria, Ricardo A. Azevedo, Luiz R. Travassos
Published 2014-01-01

Immunomodulatory Protective Effects of Rb9 Cyclic-Peptide in a Metastatic Melanoma Setting and the Involvement of Dendritic Cells

by Fabrício C. Machado, Fabrício C. Machado, Natália Girola, Natália Girola, Vera S. C. Maia, Vera S. C. Maia, Patrícia C. Bergami-Santos, Patrícia C. Bergami-Santos, Alice S. Morais, Ricardo A. Azevedo, Carlos R. Figueiredo, Carlos R. Figueiredo, José A. M. Barbuto, José A. M. Barbuto, Luiz R. Travassos, Luiz R. Travassos
Published 2020-01-01

Molecular, Biological and Structural Features of VL CDR-1 Rb44 Peptide, Which Targets the Microtubule Network in Melanoma Cells

by Natalia Girola, Pedro T. Resende-Lara, Carlos R. Figueiredo, Carlos R. Figueiredo, Mariana H. Massaoka, Ricardo A. Azevedo, Rodrigo L. O. R. Cunha, Luciano Polonelli, Luiz R. Travassos, Luiz R. Travassos
Published 2019-01-01

Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo.

by Mariana H Massaoka, Alisson L Matsuo, Carlos R Figueiredo, Camyla F Farias, Natália Girola, Denise C Arruda, Jorge A B Scutti, Paulete Romoff, Oriana A Favero, Marcelo J P Ferreira, João H G Lago, Luiz R Travassos
Published 2012-01-01

Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma

by Carlos R. Figueiredo, Carlos R. Figueiredo, Ricardo A. Azevedo, Sasha Mousdell, Pedro T. Resende-Lara, Pedro T. Resende-Lara, Lucy Ireland, Almudena Santos, Natalia Girola, Rodrigo L. O. R. Cunha, Michael C. Schmid, Luciano Polonelli, Luiz R. Travassos, Ainhoa Mielgo
Published 2018-05-01

Antitumor Activity of Kielmeyera Coriacea Leaf Constituents in Experimental Melanoma, Tested in Vitro and in Vivo in Syngeneic Mice

by Carlos Rogério Figueiredo, Alisson Leonardo Matsuo, Mariana Hiromi Massaoka, Natalia Girola, Ricardo Alexandre Azevedo, Aline Nogueira Rabaça, Camyla Fernandes Farias, Felipe Valença Pereira, Natalia Silva Matias, Luciana Pereira Silva, Elaine Guadelupe Rodrigues, João Henrique Guilardi Lago, Luiz Rodolpho Travassos, Regildo Márcio Gonçalves Silva
Published 2014-10-01