Emerging SARS-CoV-2 Variants and Impact in Global Vaccination Programs against SARS-CoV-2/COVID-19

by Carmen Elena Gómez, Beatriz Perdiguero, Mariano Esteban
Published 2021-03-01

Immune Modulation of NYVAC-Based HIV Vaccines by Combined Deletion of Viral Genes that Act on Several Signalling Pathways

by Carmen Elena Gómez, Beatriz Perdiguero, Cristina Sánchez-Corzo, Carlos Oscar S. Sorzano, Mariano Esteban
Published 2017-12-01

High quality long-term CD4+ and CD8+ effector memory populations stimulated by DNA-LACK/MVA-LACK regimen in Leishmania major BALB/c model of infection.

by Lucas Sánchez-Sampedro, Carmen Elena Gómez, Ernesto Mejías-Pérez, Carlos Oscar S Sorzano, Mariano Esteban
Published 2012-01-01

Insertion of vaccinia virus C7L host range gene into NYVAC-B genome potentiates immune responses against HIV-1 antigens.

by José Luis Nájera, Carmen Elena Gómez, Juan García-Arriaza, Carlos Oscar Sorzano, Mariano Esteban
Published 2010-01-01

A Novel MVA-Based HIV Vaccine Candidate (MVA-gp145-GPN) Co-Expressing Clade C Membrane-Bound Trimeric gp145 Env and Gag-Induced Virus-Like Particles (VLPs) Triggered Broad and Mult...

by Beatriz Perdiguero, Cristina Sánchez-Corzo, Carlos Oscar S. Sorzano, Lidia Saiz, Pilar Mediavilla, Mariano Esteban, Carmen Elena Gómez
Published 2019-02-01

Induction of Broad and Polyfunctional HIV-1-Specific T Cell Responses by the Multiepitopic Protein TMEP-B Vectored by MVA Virus

by Beatriz Perdiguero, Cristina Sánchez-Corzo, Carlos Oscar S. Sorzano, Pilar Mediavilla, Lidia Saiz, Mariano Esteban, Carmen Elena Gómez
Published 2019-06-01

Potent HIV-1-Specific CD8 T Cell Responses Induced in Mice after Priming with a Multiepitopic DNA-TMEP and Boosting with the HIV Vaccine MVA-B

by Beatriz Perdiguero, Suresh C. Raman, Cristina Sánchez-Corzo, Carlos Oscar S. Sorzano, José Ramón Valverde, Mariano Esteban, Carmen Elena Gómez
Published 2018-08-01

Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candid...

by Beatriz Perdiguero, Carmen Elena Gómez, Mauro Di Pilato, Carlos Oscar S Sorzano, Julie Delaloye, Thierry Roger, Thierry Calandra, Giuseppe Pantaleo, Mariano Esteban
Published 2013-01-01

Dendritic cells exposed to MVA-based HIV-1 vaccine induce highly functional HIV-1-specific CD8(+) T cell responses in HIV-1-infected individuals.

by Núria Climent, Susana Guerra, Felipe García, Cristina Rovira, Laia Miralles, Carmen Elena Gómez, Núria Piqué, Cristina Gil, José María Gatell, Mariano Esteban, Teresa Gallart
Published 2011-01-01

Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens.

by Beatriz Perdiguero, Carmen Elena Gómez, Jose Luis Nájera, Carlos Oscar S Sorzano, Julie Delaloye, Rubén González-Sanz, Victoria Jiménez, Thierry Roger, Thierry Calandra, Giuseppe Pantaleo, Mariano Esteban
Published 2012-01-01

Enhancement of the HIV-1-Specific Immune Response Induced by an mRNA Vaccine through Boosting with a Poxvirus MVA Vector Expressing the Same Antigen

by Carmen Elena Gómez, Beatriz Perdiguero, Lorena Usero, Laura Marcos-Villar, Laia Miralles, Lorna Leal, Carlos Óscar S. Sorzano, Cristina Sánchez-Corzo, Montserrat Plana, Felipe García, Mariano Esteban
Published 2021-08-01

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART.

by Carmen Elena Gómez, Beatriz Perdiguero, Juan García-Arriaza, Victoria Cepeda, Carlos Óscar Sánchez-Sorzano, Beatriz Mothe, José Luis Jiménez, María Ángeles Muñoz-Fernández, Jose M Gatell, Juan Carlos López Bernaldo de Quirós, Christian Brander, Felipe García, Mariano Esteban
Published 2015-01-01

Heterologous Combination of VSV-GP and NYVAC Vectors Expressing HIV-1 Trimeric gp145 Env as Vaccination Strategy to Induce Balanced B and T Cell Immune Responses

by Beatriz Perdiguero, Carmen Elena Gómez, Juan García-Arriaza, Cristina Sánchez-Corzo, Carlos Óscar S. Sorzano, Sarah Wilmschen, Dorothee von Laer, Benedikt Asbach, Christina Schmalzl, David Peterhoff, Song Ding, Ralf Wagner, Ralf Wagner, Janine Kimpel, Yves Levy, Yves Levy, Yves Levy, Giuseppe Pantaleo, Mariano Esteban
Published 2019-12-01

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C

by Carmen Elena Gómez, Beatriz Perdiguero, Victoria Jiménez, Abdelali Filali-Mouhim, Khader Ghneim, Elias K. Haddad, Esther D. Quakkerlaar, Julie Delaloye, Alexandre Harari, Thierry Roger, Thomas Duhen, Rafick P. Sékaly, Cornelis J. M. Melief, Thierry Calandra, Federica Sallusto, Antonio Lanzavecchia, Ralf Wagner, Giuseppe Pantaleo, Mariano Esteban
Published 2012-01-01

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C

by Carmen Elena Gómez, Beatriz Perdiguero, Victoria Jiménez, Abdelali Filali-Mouhim, Khader Ghneim, Elias K. Haddad, Esther D. Quakkerlaar, Julie Delaloye, Alexandre Harari, Thierry Roger, Thomas Dunhen, Rafick P. Sékaly, Cornelis J. M. Melief, Thierry Calandra, Federica Sallusto, Antonio Lanzavecchia, Ralf Wagner, Giuseppe Pantaleo, Mariano Esteban
Published 2012-01-01

Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.

by Carmen Elena Gómez, Beatriz Perdiguero, Victoria Jiménez, Abdelali Filali-Mouhim, Khader Ghneim, Elias K Haddad, Esther D Quakkelaar, Julie Delaloye, Alexandre Harari, Thierry Roger, Thomas Duhen, Rafick P Sékaly, Cornelis J M Melief, Thierry Calandra, Federica Sallusto, Antonio Lanzavecchia, Ralf Wagner, Giuseppe Pantaleo, Mariano Esteban
Published 2012-01-01

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C.

by Carmen Elena Gómez, Beatriz Perdiguero, Victoria Jiménez, Abdelali Filali-Mouhim, Khader Ghneim, Elias K. Haddad, Esther D. Quakkerlaar, Julie Delaloye, Alexandre Harari, Thierry Roger, Thomas Duhen, Rafick P. Sékaly, Cornelis J. M. Melief, Thierry Calandra, Federica Sallusto, Antonio Lanzavecchia, Ralf Wagner, Giuseppe Pantaleo, Mariano Esteban
Published 2012-01-01

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C.

by Carmen Elena Gómez, Beatriz Perdiguero, Victoria Jiménez, Abdelali Filali-Mouhim, Khader Ghneim, Elias K. Haddad, Esther D. Quakkerlaar, Julie Delaloye, Alexandre Harari, Thierry Roger, Thomas Dunhen, Rafick P. Sékaly, Cornelis J. M. Melief, Thierry Calandra, Federica Sallusto, Antonio Lanzavecchia, Ralf Wagner, Giuseppe Pantaleo, Mariano Esteban
Published 2012-01-01

Correction: Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization.

by Alberto C Guardo, Carmen Elena Gómez, Vicens Díaz-Brito, Judit Pich, Joan Albert Arnaiz, Beatriz Perdiguero, Juan García-Arriaza, Nuria González, Carlos O S Sorzano, Laura Jiménez, José Luis Jiménez, María Ángeles Muñoz-Fernández, José M Gatell, José Alcamí, Mariano Esteban, Juan Carlos López Bernaldo de Quirós, Felipe García, Montserrat Plana, RISVAC02boost study
Published 2018-01-01

Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization.

by Alberto C Guardo, Carmen Elena Gómez, Vicens Díaz-Brito, Judit Pich, Joan Albert Arnaiz, Beatriz Perdiguero, Juan García-Arriaza, Nuria González, Carlos O S Sorzano, Laura Jiménez, José Luis Jiménez, María Ángeles Muñoz-Fernández, José M Gatell, José Alcamí, Mariano Esteban, Juan Carlos López Bernaldo de Quirós, Felipe García, Montserrat Plana, RISVAC02boost study
Published 2017-01-01