High Conservation of Tetanus and Botulinum Neurotoxins Cleavage Sites on Human SNARE Proteins Suggests That These Pathogens Exerted Little or No Evolutionary Pressure on Humans

by Stefan Carle, Marco Pirazzini, Ornella Rossetto, Holger Barth, Cesare Montecucco
Published 2017-12-01

Correction: Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases

by Andrea Puhar, Federica Dal Molin, Stéphanie Horvath, Daniel Ladant, Cesare Montecucco
Published 2008-01-01

Anthrax edema toxin modulates PKA- and CREB-dependent signaling in two phases.

by Andrea Puhar, Federica Dal Molin, Stéphanie Horvath, Daniel Ladant, Cesare Montecucco
Published 2008-01-01

Correction: Anthrax Edema Toxin Modulates PKA- and CREB-Dependent Signaling in Two Phases.

by Andrea Puhar, Federica Dal Molin, Stéphanie Horvath, Daniel Ladant, Cesare Montecucco
Published 2008-01-01

Synergism between basic Asp49 and Lys49 phospholipase A2 myotoxins of viperid snake venom in vitro and in vivo.

by Diana Mora-Obando, Julián Fernández, Cesare Montecucco, José María Gutiérrez, Bruno Lomonte
Published 2014-01-01

Envenomations by Bothrops and Crotalus snakes induce the release of mitochondrial alarmins.

by Irene Zornetta, Paola Caccin, Julián Fernandez, Bruno Lomonte, José María Gutierrez, Cesare Montecucco
Published 2012-01-01

Snake and Spider Toxins Induce a Rapid Recovery of Function of Botulinum Neurotoxin Paralysed Neuromuscular Junction

by Elisa Duregotti, Giulia Zanetti, Michele Scorzeto, Aram Megighian, Cesare Montecucco, Marco Pirazzini, Michela Rigoni
Published 2015-12-01

Semicarbazone EGA Inhibits Uptake of Diphtheria Toxin into Human Cells and Protects Cells from Intoxication

by Leonie Schnell, Ann-Katrin Mittler, Andrea Mattarei, Domenico Azarnia Tehran, Cesare Montecucco, Holger Barth
Published 2016-07-01

Schwann cells are activated by ATP released from neurons in an in vitro cellular model of Miller Fisher syndrome

by Umberto Rodella, Samuele Negro, Michele Scorzeto, Elisanna Bergamin, Kees Jalink, Cesare Montecucco, Nobuhiro Yuki, Michela Rigoni
Published 2017-05-01

Detection of Clostridium tetani Neurotoxins Inhibited In Vivo by Botulinum Antitoxin B: Potential for Misleading Mouse Test Results in Food Controls

by Luca Bano, Elena Tonon, Ilenia Drigo, Marco Pirazzini, Angela Guolo, Giovanni Farina, Fabrizio Agnoletti, Cesare Montecucco
Published 2018-06-01

An agonist of the CXCR4 receptor accelerates the recovery from the peripheral neuroparalysis induced by Taipan snake envenomation.

by Marco Stazi, Giorgia D'Este, Andrea Mattarei, Samuele Negro, Florigio Lista, Michela Rigoni, Aram Megighian, Cesare Montecucco
Published 2020-09-01

A CXCR4 receptor agonist strongly stimulates axonal regeneration after damage

by Giulia Zanetti, Samuele Negro, Aram Megighian, Andrea Mattarei, Florigio Lista, Silvia Fillo, Michela Rigoni, Marco Pirazzini, Cesare Montecucco
Published 2019-12-01

The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling.

by Silvia Rossi Paccani, Marisa Benagiano, Nagaja Capitani, Irene Zornetta, Daniel Ladant, Cesare Montecucco, Mario M D'Elios, Cosima T Baldari
Published 2009-03-01

Electrophysiological Characterization of the Antarease Metalloprotease from Tityus serrulatus Venom

by Irene Zornetta, Michele Scorzeto, Pablo Victor Mendes Dos Reis, Maria E. De Lima, Cesare Montecucco, Aram Megighian, Ornella Rossetto
Published 2017-02-01

An animal model of Miller Fisher syndrome: Mitochondrial hydrogen peroxide is produced by the autoimmune attack of nerve terminals and activates Schwann cells

by Umberto Rodella, Michele Scorzeto, Elisa Duregotti, Samuele Negro, Bryan C. Dickinson, Christopher J. Chang, Nobuhiro Yuki, Michela Rigoni, Cesare Montecucco
Published 2016-12-01

Repair of a Bacterial Small β-Barrel Toxin Pore Depends on Channel Width

by Gisela von Hoven, Amable J. Rivas, Claudia Neukirch, Martina Meyenburg, Qianqian Qin, Sapun Parekh, Nadja Hellmann, Matthias Husmann, Cesare Montecucco, Arturo Zychlinsky
Published 2017-02-01

EGA Protects Mammalian Cells from Clostridium difficile CDT, Clostridium perfringens Iota Toxin and Clostridium botulinum C2 Toxin

by Leonie Schnell, Ann-Katrin Mittler, Mirko Sadi, Michel R. Popoff, Carsten Schwan, Klaus Aktories, Andrea Mattarei, Domenico Azarnia Tehran, Cesare Montecucco, Holger Barth
Published 2016-04-01

Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins

by Marco Pirazzini, Domenico Azarnia Tehran, Giulia Zanetti, Aram Megighian, Michele Scorzeto, Silvia Fillo, Clifford C. Shone, Thomas Binz, Ornella Rossetto, Florigio Lista, Cesare Montecucco
Published 2014-09-01

An Agonist of the CXCR4 Receptor Strongly Promotes Regeneration of Degenerated Motor Axon Terminals

by Samuele Negro, Giulia Zanetti, Andrea Mattarei, Alice Valentini, Aram Megighian, Giulia Tombesi, Alessandro Zugno, Valentina Dianin, Marco Pirazzini, Silvia Fillo, Florigio Lista, Michela Rigoni, Cesare Montecucco
Published 2019-09-01

The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65.

by Daniela S Silva, Daniela S Silva, Liliana M G Pereira, Ana R Moreira, Frederico Ferreira-da-Silva, Rui M Brito, Tiago Q Faria, Irene Zornetta, Cesare Montecucco, Pedro Oliveira, Jorge E Azevedo, Pedro J B Pereira, Sandra Macedo-Ribeiro, Ana do Vale, Nuno M S dos Santos
Published 2013-02-01