Mitochondrial Dysfunction as Substrate for Arrhythmogenic Cardiomyopathy: A Search for New Disease Mechanisms

by Chantal J. M. van Opbergen, Lyanne den Braven, Mario Delmar, Toon A. B. van Veen
Published 2019-12-01

In silico Identification of Disrupted Myocardial Calcium Homeostasis as Proarrhythmic Trigger in Arrhythmogenic Cardiomyopathy

by Aurore Lyon, Chantal J. M. van Opbergen, Mario Delmar, Jordi Heijman, Toon A. B. van Veen
Published 2021-09-01

Blockade of the Adenosine 2A Receptor Mitigates the Cardiomyopathy Induced by Loss of Plakophilin-2 Expression

by Marina Cerrone, Chantal J. M. van Opbergen, Kabir Malkani, Natasha Irrera, Natasha Irrera, Mingliang Zhang, Toon A. B. Van Veen, Bruce Cronstein, Mario Delmar
Published 2018-12-01

Transcriptomic Coupling of PKP2 With Inflammatory and Immune Pathways Endogenous to Adult Cardiac Myocytes

by Marta Pérez-Hernández, Grecia M. Marrón-Liñares, Florencia Schlamp, Adriana Heguy, Chantal J. M. van Opbergen, Valeria Mezzano, Mingliang Zhang, Feng-Xia Liang, Marina Cerrone, Mario Delmar
Published 2021-01-01

Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress

by Chantal J.M. van Opbergen, Maartje Noorman, Anna Pfenniger, Jaël S. Copier, Sarah H. Vermij, Zhen Li, Roel van der Nagel, Mingliang Zhang, Jacques M.T. de Bakker, Aaron M. Glass, Peter J. Mohler, Steven M. Taffet, Marc A. Vos, Harold V.M. van Rijen, Mario Delmar, Toon A.B. van Veen
Published 2019-08-01

Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm

by Marina Cerrone, Jerome Montnach, Xianming Lin, Yan-Ting Zhao, Mingliang Zhang, Esperanza Agullo-Pascual, Alejandra Leo-Macias, Francisco J. Alvarado, Igor Dolgalev, Thomas V. Karathanos, Kabir Malkani, Chantal J.M. Van Opbergen, Joanne J.A. van Bavel, Hua-Qian Yang, Carolina Vasquez, David Tester, Steven Fowler, Fengxia Liang, Eli Rothenberg, Adriana Heguy, Gregory E. Morley, William A. Coetzee, Natalia A. Trayanova, Michael J. Ackerman, Toon A.B. van Veen, Hector H. Valdivia, Mario Delmar
Published 2017-07-01