Towards Creating the Perfect In Vitro Cell Model

by Malin K. B. Jonsson, Toon A. B. van Veen, Jane Synnergren, Bruno Becker
Published 2016-01-01

Sex-specific influence on cardiac structural remodeling and therapy in cardiovascular disease

by Elise L. Kessler, Mathilde R. Rivaud, Marc A. Vos, Toon A. B. van Veen
Published 2019-02-01

Mitochondrial Dysfunction as Substrate for Arrhythmogenic Cardiomyopathy: A Search for New Disease Mechanisms

by Chantal J. M. van Opbergen, Lyanne den Braven, Mario Delmar, Toon A. B. van Veen
Published 2019-12-01

In silico Identification of Disrupted Myocardial Calcium Homeostasis as Proarrhythmic Trigger in Arrhythmogenic Cardiomyopathy

by Aurore Lyon, Chantal J. M. van Opbergen, Mario Delmar, Jordi Heijman, Toon A. B. van Veen
Published 2021-09-01

A 50% reduction of excitability but not of intercellular coupling affects conduction velocity restitution and activation delay in the mouse heart.

by Mèra Stein, Toon A B van Veen, Richard N W Hauer, Jacques M T de Bakker, Harold V M van Rijen
Published 2011-01-01

Assembly of the cardiac intercalated disk during pre- and postnatal development of the human heart.

by Arnold Vreeker, Leonie van Stuijvenberg, Thomas J Hund, Peter J Mohler, Peter G J Nikkels, Toon A B van Veen
Published 2014-01-01

Passive ventricular remodeling in cardiac disease: Focus on heterogeneity

by Elise L Kessler, Mohamed eBoulaksil, Mohamed eBoulaksil, Harold V.M Van Rijen, Marc A Vos, Toon A.B. Van Veen
Published 2014-12-01

A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Tim...

by Birgit Goversen, Nadine Becker, Sonja Stoelzle-Feix, Alison Obergrussberger, Marc A. Vos, Toon A. B. van Veen, Niels Fertig, Teun P. de Boer
Published 2018-01-01

Blockade of the Adenosine 2A Receptor Mitigates the Cardiomyopathy Induced by Loss of Plakophilin-2 Expression

by Marina Cerrone, Chantal J. M. van Opbergen, Kabir Malkani, Natasha Irrera, Natasha Irrera, Mingliang Zhang, Toon A. B. Van Veen, Bruce Cronstein, Mario Delmar
Published 2018-12-01

A Proteomics Approach to Identify New Putative Cardiac Intercalated Disk Proteins.

by Siddarth Soni, Antonia J A Raaijmakers, Linsey M Raaijmakers, J Mirjam A Damen, Leonie van Stuijvenberg, Marc A Vos, Albert J R Heck, Toon A B van Veen, Arjen Scholten
Published 2016-01-01

Analysis of 24-h Rhythm in Ventricular Repolarization Identifies QT Diurnality As a Novel Clinical Parameter Associated with Previous Ventricular Arrhythmias in Heart Failure Patie...

by Bastiaan C. Du Pre, Bastiaan C. Du Pre, Linda W. Van Laake, Matthias Meine, Jeroen F. Van der Heijden, Pieter A. Doevendans, Marc A. Vos, Toon A. B. Van Veen
Published 2017-08-01

A Transcriptomic and Epigenomic Comparison of Fetal and Adult Human Cardiac Fibroblasts Reveals Novel Key Transcription Factors in Adult Cardiac Fibroblasts

by Malin K.B. Jonsson, PhD, Robin J.G. Hartman, MSc, Matthew Ackers-Johnson, PhD, Wilson L.W. Tan, BSc, Bing Lim, MD, PhD, Toon A.B. van Veen, PhD, Roger S. Foo, MD
Published 2016-12-01

SCA1+ Cells from the Heart Possess a Molecular Circadian Clock and Display Circadian Oscillations in Cellular Functions

by Bastiaan C. Du Pré, Evelyne J. Demkes, Dries A.M. Feyen, Pieterjan Dierickx, Sandra Crnko, Bart J.M. Kok, Joost P.G. Sluijter, Pieter A. Doevendans, Marc A. Vos, Toon A.B. Van Veen, Linda W. Van Laake
Published 2017-09-01

Leukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure Overload

by Jiong-Wei Wang, Magda S. C. Fontes, Xiaoyuan Wang, Suet Yen Chong, Elise L. Kessler, Ya-Nan Zhang, Judith J. de Haan, Fatih Arslan, Saskia C. A. de Jager, Leo Timmers, Toon A. B. van Veen, Carolyn S. P. Lam, Dominique P. V. de Kleijn
Published 2017-08-01

Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress

by Chantal J.M. van Opbergen, Maartje Noorman, Anna Pfenniger, Jaël S. Copier, Sarah H. Vermij, Zhen Li, Roel van der Nagel, Mingliang Zhang, Jacques M.T. de Bakker, Aaron M. Glass, Peter J. Mohler, Steven M. Taffet, Marc A. Vos, Harold V.M. van Rijen, Mario Delmar, Toon A.B. van Veen
Published 2019-08-01

Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing

by Anna M. D. Végh, A. Dénise den Haan, Lucía Cócera Ortega, Arie O. Verkerk, Joost P. G. Sluijter, Diane Bakker, Shirley van Amersfoorth, Toon A. B. van Veen, Mischa Klerk, Jurgen Seppen, Jacques M. T. de Bakker, Vincent M. Christoffels, Dirk Geerts, Marie José T. H. Goumans, Hanno L. Tan, Gerard J. J. Boink
Published 2019-01-01

Spatial Heterogeneity of Cx43 Is an Arrhythmogenic Substrate of Polymorphic Ventricular Tachycardias during Compensated Cardiac Hypertrophy in Rats

by Mohamed eBoulaksil, Mohamed eBoulaksil, Mohamed eBoulaksil, Marti F.A. Bierhuizen, Markus A.B. Engelen, Markus A.B. Engelen, Mera eStein, Mera eStein, Bart J.M. Kok, Shirley C.M. van Amersfoorth, Marc A Vos, Harold V.M. Van Rijen, Jacques MT De Bakker, Jacques MT De Bakker, Jacques MT De Bakker, Toon A.B. Van Veen
Published 2016-03-01

Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm

by Marina Cerrone, Jerome Montnach, Xianming Lin, Yan-Ting Zhao, Mingliang Zhang, Esperanza Agullo-Pascual, Alejandra Leo-Macias, Francisco J. Alvarado, Igor Dolgalev, Thomas V. Karathanos, Kabir Malkani, Chantal J.M. Van Opbergen, Joanne J.A. van Bavel, Hua-Qian Yang, Carolina Vasquez, David Tester, Steven Fowler, Fengxia Liang, Eli Rothenberg, Adriana Heguy, Gregory E. Morley, William A. Coetzee, Natalia A. Trayanova, Michael J. Ackerman, Toon A.B. van Veen, Hector H. Valdivia, Mario Delmar
Published 2017-07-01