[11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels.

by W Gordon Frankle, Raymond Y Cho, N Scott Mason, Chi-Min Chen, Michael Himes, Christopher Walker, David A Lewis, Chester A Mathis, Rajesh Narendran
Published 2012-01-01

Comparison of qualitative and quantitative imaging characteristics of [11C]PiB and [18F]flutemetamol in normal control and Alzheimer's subjects

by James M. Mountz, Charles M. Laymon, Ann D. Cohen, Zheng Zhang, Julie C. Price, Sanaa Boudhar, Eric McDade, Howard J. Aizenstein, William E. Klunk, Chester A. Mathis
Published 2015-01-01

Impact of partial volume correction on the regional correspondence between in vivo [C-11]PiB PET and postmortem measures of Aβ load

by Davneet S. Minhas, Julie C. Price, Charles M. Laymon, Carl R. Becker, William E. Klunk, Dana L. Tudorascu, Eric E. Abrahamson, Ronald L. Hamilton, Julia K. Kofler, Chester A. Mathis, Oscar L. Lopez, Milos D. Ikonomovic
Published 2018-01-01

PET measurement of longitudinal amyloid load identifies the earliest stages of amyloid-beta accumulation during Alzheimer's disease progression in Down syndrome

by Matthew D. Zammit, Dana L. Tudorascu, Charles M. Laymon, Sigan L. Hartley, Shahid H. Zaman, Beau M. Ances, Sterling C. Johnson, Charles K. Stone, Chester A. Mathis, William E. Klunk, Ann D. Cohen, Benjamin L. Handen, Bradley T. Christian
Published 2021-03-01

Patterns of glucose hypometabolism in Down syndrome resemble sporadic Alzheimer's disease except for the putamen

by Matthew D. Zammit, Charles M. Laymon, Dana L. Tudorascu, Sigan L. Hartley, Brianna Piro‐Gambetti, Sterling C. Johnson, Charles K. Stone, Chester A. Mathis, Shahid H. Zaman, William E. Klunk, Benjamin L. Handen, Ann D. Cohen, Bradley T. Christian
Published 2020-01-01

Amyloid accumulation in Down syndrome measured with amyloid load

by Matthew D. Zammit, Charles M. Laymon, Tobey J. Betthauser, Karly A. Cody, Dana L. Tudorascu, Davneet S. Minhas, Marwan N. Sabbagh, Sterling C. Johnson, Shahid H. Zaman, Chester A. Mathis, William E. Klunk, Benjamin L. Handen, Ann D. Cohen, Bradley T. Christian
Published 2020-01-01

Comparing Pathological Risk Factors for Dementia between Cognitively Normal Japanese and Americans

by Chendi Cui, Aya Higashiyama, Brian J. Lopresti, Masafumi Ihara, Howard J. Aizenstein, Makoto Watanabe, Yuefang Chang, Chikage Kakuta, Zheming Yu, Chester A. Mathis, Yoshihiro Kokubo, Tetsuya Fukuda, Victor L. Villemagne, William E. Klunk, Oscar L. Lopez, Lewis H. Kuller, Yoshihiro Miyamoto, Akira Sekikawa
Published 2021-09-01

Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome

by Matthew D. Zammit, Dana L. Tudorascu, Charles M. Laymon, Sigan L. Hartley, Paul A. Ellison, Shahid H. Zaman, Beau M. Ances, Sterling C. Johnson, Charles K. Stone, Marwan N. Sabbagh, Chester A. Mathis, William E. Klunk, Ann D. Cohen, Benjamin L. Handen, Bradley T. Christian
Published 2021-01-01

[18F]FDG, [11C]PiB, and [18F]AV-1451 PET Imaging of Neurodegeneration in Two Subjects With a History of Repetitive Trauma and Cognitive Decline

by David O. Okonkwo, Ross C. Puffer, Davneet S. Minhas, Sue R. Beers, Kathryn L. Edelman, Jane Sharpless, Charles M. Laymon, Brian J. Lopresti, Steven Benso, Ava M. Puccio, Sudhir Pathak, Milos D. Ikonomovic, Milos D. Ikonomovic, Joseph M. Mettenburg, Walter Schneider, Chester A. Mathis, James M. Mountz
Published 2019-08-01