Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

by Jose L. Martinez, Jose L. Martinez, Matthew D. Zammit, Matthew D. Zammit, Nicole R. West, Nicole R. West, Bradley T. Christian, Bradley T. Christian, Bradley T. Christian, Anita Bhattacharyya, Anita Bhattacharyya
Published 2021-07-01

Corrigendum: Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer's Disease

by Jose L. Martinez, Jose L. Martinez, Matthew D. Zammit, Matthew D. Zammit, Nicole R. West, Nicole R. West, Bradley T. Christian, Bradley T. Christian, Bradley T. Christian, Anita Bhattacharyya, Anita Bhattacharyya
Published 2021-08-01

Cognitive indicators of transition to preclinical and prodromal stages of Alzheimer's disease in Down syndrome

by Sigan L. Hartley, Benjamin L. Handen, Darlynne Devenny, Dana Tudorascu, Brianna Piro‐Gambetti, Matthew D. Zammit, Charles M. Laymon, William E. Klunk, Shahid Zaman, Annie Cohen, Bradley T. Christian
Published 2020-01-01

Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome

by Rachel L. Henson, Eric Doran, Bradley T. Christian, Benjamin L. Handen, William E. Klunk, Florence Lai, Joseph H. Lee, H. Diana Rosas, Nicole Schupf, Shahid H. Zaman, Ira T. Lott, Anne M. Fagan
Published 2020-01-01

The use of Centiloids for applying [11C]PiB classification cutoffs across region‐of‐interest delineation methods

by Dana L. Tudorascu, Davneet S. Minhas, Patrick J. Lao, Tobey J. Betthauser, Zheming Yu, Charles M. Laymon, Brian J. Lopresti, Chet A. Mathis, William E. Klunk, Benjamin L. Handen, Bradley T. Christian, Ann D. Cohen
Published 2018-01-01

[ 18F]FEPPA PET imaging for monitoring CD68-positive microglia/macrophage neuroinflammation in nonhuman primates

by Matthew Zammit, Yunlong Tao, Miles E. Olsen, Jeanette Metzger, Scott C. Vermilyea, Kathryn Bjornson, Maxim Slesarev, Walter F. Block, Kerri Fuchs, Sean Phillips, Viktorya Bondarenko, Su-Chun Zhang, Marina E. Emborg, Bradley T. Christian
Published 2020-08-01

Metabolic correlates of prevalent mild cognitive impairment and Alzheimer's disease in adults with Down syndrome

by Mark Mapstone, Thomas J Gross, Fabio Macciardi, Amrita K Cheema, Melissa Petersen, Elizabeth Head, Benjamin L Handen, William E Klunk, Bradley T Christian, Wayne Silverman, Ira T Lott, Nicole Schupf, for the Alzheimer's Biomarkers Consortium–Down Syndrome (ABC‐DS) Investigators
Published 2020-01-01

PET measurement of longitudinal amyloid load identifies the earliest stages of amyloid-beta accumulation during Alzheimer's disease progression in Down syndrome

by Matthew D. Zammit, Dana L. Tudorascu, Charles M. Laymon, Sigan L. Hartley, Shahid H. Zaman, Beau M. Ances, Sterling C. Johnson, Charles K. Stone, Chester A. Mathis, William E. Klunk, Ann D. Cohen, Benjamin L. Handen, Bradley T. Christian
Published 2021-03-01

Patterns of glucose hypometabolism in Down syndrome resemble sporadic Alzheimer's disease except for the putamen

by Matthew D. Zammit, Charles M. Laymon, Dana L. Tudorascu, Sigan L. Hartley, Brianna Piro‐Gambetti, Sterling C. Johnson, Charles K. Stone, Chester A. Mathis, Shahid H. Zaman, William E. Klunk, Benjamin L. Handen, Ann D. Cohen, Bradley T. Christian
Published 2020-01-01

Amyloid accumulation in Down syndrome measured with amyloid load

by Matthew D. Zammit, Charles M. Laymon, Tobey J. Betthauser, Karly A. Cody, Dana L. Tudorascu, Davneet S. Minhas, Marwan N. Sabbagh, Sterling C. Johnson, Shahid H. Zaman, Chester A. Mathis, William E. Klunk, Benjamin L. Handen, Ann D. Cohen, Bradley T. Christian
Published 2020-01-01

Amyloid duration is associated with preclinical cognitive decline and tau PET

by Rebecca L. Koscik, Tobey J. Betthauser, Erin M. Jonaitis, Samantha L. Allison, Lindsay R. Clark, Bruce P. Hermann, Karly A. Cody, Jonathan W. Engle, Todd E. Barnhart, Charles K. Stone, Nathaniel A. Chin, Cynthia M. Carlsson, Sanjay Asthana, Bradley T. Christian, Sterling C. Johnson
Published 2020-01-01

Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep‐phenotyping case report

by Elijah Mak, Anastasia Bickerton, Concepcion Padilla, Madeleine J. Walpert, Tiina Annus, Liam R. Wilson, Young T. Hong, Tim D. Fryer, Jonathan P. Coles, Franklin I. Aigbirhio, Bradley T. Christian, Benjamin L. Handen, William E. Klunk, David K. Menon, Peter J. Nestor, Shahid H. Zaman, Anthony J. Holland
Published 2019-12-01

Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome

by Matthew D. Zammit, Dana L. Tudorascu, Charles M. Laymon, Sigan L. Hartley, Paul A. Ellison, Shahid H. Zaman, Beau M. Ances, Sterling C. Johnson, Charles K. Stone, Marwan N. Sabbagh, Chester A. Mathis, William E. Klunk, Ann D. Cohen, Benjamin L. Handen, Bradley T. Christian
Published 2021-01-01

Measuring longitudinal cognition: Individual tests versus composites

by Erin M. Jonaitis, Rebecca L. Koscik, Lindsay R. Clark, Yue Ma, Tobey J. Betthauser, Sara E. Berman, Samantha L. Allison, Kimberly D. Mueller, Bruce P. Hermann, Carol A. Van Hulle, Bradley T. Christian, Barbara B. Bendlin, Kaj Blennow, Henrik Zetterberg, Cynthia M. Carlsson, Sanjay Asthana, Sterling C. Johnson
Published 2019-12-01

Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation

by Annie M. Racine, Nagesh Adluru, Andrew L. Alexander, Bradley T. Christian, Ozioma C. Okonkwo, Jennifer Oh, Caitlin A. Cleary, Alex Birdsill, Ansel T. Hillmer, Dhanabalan Murali, Todd E. Barnhart, Catherine L. Gallagher, Cynthia M. Carlsson, Howard A. Rowley, N. Maritza Dowling, Sanjay Asthana, Mark A. Sager, Barbara B. Bendlin, Sterling C. Johnson
Published 2014-01-01

Validity Evidence for the Research Category, “Cognitively Unimpaired – Declining,” as a Risk Marker for Mild Cognitive Impairment and Alzheimer’s Disease

by Rebecca Langhough Koscik, Rebecca Langhough Koscik, Rebecca Langhough Koscik, Bruce P. Hermann, Bruce P. Hermann, Bruce P. Hermann, Samantha Allison, Samantha Allison, Samantha Allison, Lindsay R. Clark, Lindsay R. Clark, Lindsay R. Clark, Erin M. Jonaitis, Erin M. Jonaitis, Erin M. Jonaitis, Kimberly D. Mueller, Kimberly D. Mueller, Kimberly D. Mueller, Kimberly D. Mueller, Tobey J. Betthauser, Tobey J. Betthauser, Tobey J. Betthauser, Bradley T. Christian, Bradley T. Christian, Lianlian Du, Lianlian Du, Ozioma Okonkwo, Ozioma Okonkwo, Ozioma Okonkwo, Alex Birdsill, Alex Birdsill, Alex Birdsill, Nathaniel Chin, Nathaniel Chin, Carey Gleason, Carey Gleason, Carey Gleason, Sterling C. Johnson, Sterling C. Johnson, Sterling C. Johnson, Sterling C. Johnson
Published 2021-07-01

PET Measures of D1, D2, and DAT Binding Are Associated With Heightened Tactile Responsivity in Rhesus Macaques: Implications for Sensory Processing Disorder

by Mary L. Schneider, Mary L. Schneider, Colleen F. Moore, Colleen F. Moore, Elizabeth O. Ahlers, Todd E. Barnhart, Bradley T. Christian, Onofre T. DeJesus, Jonathan W. Engle, James E. Holden, Julie A. Larson, Julie A. Larson, Jeffrey M. Moirano, Dhanabalan Murali, Robert J. Nickles, Leslie M. Resch, Leslie M. Resch, Alexander K. Converse
Published 2019-07-01

The Alzheimer's Biomarker Consortium‐Down Syndrome: Rationale and methodology

by Benjamin L. Handen, Ira T. Lott, Bradley T. Christian, Nicole Schupf, Sid OBryant, Mark Mapstone, Anne M. Fagan, Joseph H. Lee, Dana Tudorascu, Mei‐Cheng Wang, Elizabeth Head, William Klunk, Beau Ances, Florence Lai, Shahid Zaman, Sharon Krinsky‐McHale, Adam M. Brickman, H. Diana Rosas, Annie Cohen, Howard Andrews, Sigan Hartley, Wayne Silverman, the Alzheimer's Biomarker Consortium‐Down Syndrome (ABC‐DS)
Published 2020-01-01