Aging and Down Syndrome

by Elizabeth Head, Wayne Silverman, David Patterson, Ira T. Lott
Published 2012-01-01

Oxidation of Aβ and Plaque Biogenesis in Alzheimer's Disease and Down Syndrome

by Elizabeth Head, William Garzon-Rodriguez, Julene K. Johnson, Ira T. Lott, Carl W. Cotman, Charles Glabe
Published 2001-10-01

Complement Association with Neurons and β-Amyloid Deposition in the Brains of Aged Individuals with Down Syndrome

by Elizabeth Head, Bassem Y. Azizeh, Ira T. Lott, Andrea J. Tenner, Carl W. Cotman, David H. Cribbs
Published 2001-04-01

Cerebrovascular pathology in Down syndrome and Alzheimer disease

by Elizabeth Head, Michael J. Phelan, Eric Doran, Ronald C. Kim, Wayne W. Poon, Frederick A. Schmitt, Ira T. Lott
Published 2017-12-01

Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome

by Alessandra C. Martini, Alex M. Helman, Katie L. McCarty, Ira T. Lott, Eric Doran, Frederick A. Schmitt, Elizabeth Head
Published 2020-01-01

Cognitive and Behavioral Domains That Reliably Differentiate Normal Aging and Dementia in Down Syndrome

by Jordan P. Harp, Lisa M. Koehl, Kathryn L. Van Pelt, Christy L. Hom, Eric Doran, Elizabeth Head, Ira T. Lott, Frederick A. Schmitt
Published 2021-08-01

Cognitive Function during the Prodromal Stage of Alzheimer’s Disease in Down Syndrome: Comparing Models

by Christy L. Hom, Katharine A. Kirby, Joni Ricks-Oddie, David B. Keator, Sharon J. Krinsky-McHale, Margaret B. Pulsifer, Herminia Diana Rosas, Florence Lai, Nicole Schupf, Ira T. Lott, Wayne Silverman
Published 2021-09-01

Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome

by Rachel L. Henson, Eric Doran, Bradley T. Christian, Benjamin L. Handen, William E. Klunk, Florence Lai, Joseph H. Lee, H. Diana Rosas, Nicole Schupf, Shahid H. Zaman, Ira T. Lott, Anne M. Fagan
Published 2020-01-01

Postmortem Neocortical 3H-PiB Binding and Levels of Unmodified and Pyroglutamate Aβ in Down Syndrome and Sporadic Alzheimer’s Disease

by Violetta N. Pivtoraiko, Violetta N. Pivtoraiko, Tamara Racic, Eric E. Abrahamson, Eric E. Abrahamson, Victor L. Villemagne, Benjamin L. Handen, Ira T. Lott, Elizabeth Head, Milos D. Ikonomovic, Milos D. Ikonomovic, Milos D. Ikonomovic
Published 2021-08-01

Brain amyloid and the transition to dementia in Down syndrome

by David B. Keator, Eric Doran, Lisa Taylor, Michael J. Phelan, Christy Hom, Katherine Tseung, Theo G. M. vanErp, Steven G. Potkin, Adam M. Brickman, Diana H. Rosas, Michael A. Yassa, Wayne Silverman, Ira T. Lott
Published 2020-01-01

Metabolic correlates of prevalent mild cognitive impairment and Alzheimer's disease in adults with Down syndrome

by Mark Mapstone, Thomas J Gross, Fabio Macciardi, Amrita K Cheema, Melissa Petersen, Elizabeth Head, Benjamin L Handen, William E Klunk, Bradley T Christian, Wayne Silverman, Ira T Lott, Nicole Schupf, for the Alzheimer's Biomarkers Consortium–Down Syndrome (ABC‐DS) Investigators
Published 2020-01-01

Down syndrome: Distribution of brain amyloid in mild cognitive impairment

by David B. Keator, Michael J. Phelan, Lisa Taylor, Eric Doran, Sharon Krinsky‐McHale, Julie Price, Erin E. Ballard, William C. Kreisl, Christy Hom, Dana Nguyen, Margaret Pulsifer, Florence Lai, Diana H. Rosas, Adam M. Brickman, Nicole Schupf, Michael A. Yassa, Wayne Silverman, Ira T. Lott
Published 2020-01-01

The Alzheimer's Biomarker Consortium‐Down Syndrome: Rationale and methodology

by Benjamin L. Handen, Ira T. Lott, Bradley T. Christian, Nicole Schupf, Sid OBryant, Mark Mapstone, Anne M. Fagan, Joseph H. Lee, Dana Tudorascu, Mei‐Cheng Wang, Elizabeth Head, William Klunk, Beau Ances, Florence Lai, Shahid Zaman, Sharon Krinsky‐McHale, Adam M. Brickman, H. Diana Rosas, Annie Cohen, Howard Andrews, Sigan Hartley, Wayne Silverman, the Alzheimer's Biomarker Consortium‐Down Syndrome (ABC‐DS)
Published 2020-01-01