Multi-functional DNA nanostructures that puncture and remodel lipid membranes into hybrid materials

by Oliver Birkholz, Jonathan R. Burns, Christian P. Richter, Olympia E. Psathaki, Stefan Howorka, Jacob Piehler
Published 2018-04-01

A trafficome-wide RNAi screen reveals deployment of early and late secretory host proteins and the entire late endo-/lysosomal vesicle fusion machinery by intracellular Salmonella.

by Alexander Kehl, Vera Göser, Tatjana Reuter, Viktoria Liss, Maximilian Franke, Christopher John, Christian P Richter, Jörg Deiwick, Michael Hensel
Published 2020-07-01

Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilization

by Jakob C. Stüber, Christian P. Richter, Junel Sotolongo Bellón, Martin Schwill, Iwo König, Benjamin Schuler, Jacob Piehler, Andreas Plückthun
Published 2021-06-01

Nanoscopic anatomy of dynamic multi-protein complexes at membranes resolved by graphene-induced energy transfer

by Nadia Füllbrunn, Zehao Li, Lara Jorde, Christian P Richter, Rainer Kurre, Lars Langemeyer, Changyuan Yu, Carola Meyer, Jörg Enderlein, Christian Ungermann, Jacob Piehler, Changjiang You
Published 2021-01-01

Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action

by Florian Kast, Martin Schwill, Jakob C. Stüber, Svende Pfundstein, Gabriela Nagy-Davidescu, Josep M. Monné Rodríguez, Frauke Seehusen, Christian P. Richter, Annemarie Honegger, Karen Patricia Hartmann, Thomas G. Weber, Felix Kroener, Patrick Ernst, Jacob Piehler, Andreas Plückthun
Published 2021-06-01