Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation

by Kenji Onoue, Kenji Onoue, Hiroko Wakimoto, Jiangming Jiang, Michael Parfenov, Steven DePalma, David Conner, Joshua Gorham, David McKean, Jonathan G. Seidman, Christine E. Seidman, Christine E. Seidman, Yoshihiko Saito
Published 2021-06-01

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes

by Lorenzo Alamo, James S Ware, Antonio Pinto, Richard E Gillilan, Jonathan G Seidman, Christine E Seidman, Raúl Padrón
Published 2017-06-01

A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects

by Amina Kamar, Akl C. Fahed, Akl C. Fahed, Akl C. Fahed, Kamel Shibbani, Nehme El-Hachem, Salim Bou-Slaiman, Mariam Arabi, Mazen Kurban, Mazen Kurban, Mazen Kurban, Jonathan G. Seidman, Christine E. Seidman, Christine E. Seidman, Rachid Haidar, Elias Baydoun, Georges Nemer, Fadi Bitar
Published 2017-12-01

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFβR3 In Vitro.

by Daniel M DeLaughter, Cynthia R Clark, Danos C Christodoulou, Christine E Seidman, H Scott Baldwin, J G Seidman, Joey V Barnett
Published 2016-01-01

Dynamic Cellular Integration Drives Functional Assembly of the Heart’s Pacemaker Complex

by Michael Bressan, Trevor Henley, Jonathan D. Louie, Gary Liu, Danos Christodoulou, Xue Bai, Joan Taylor, Christine E. Seidman, J.G. Seidman, Takashi Mikawa
Published 2018-05-01

Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers

by Javier Diez, Begoña López, Barry J Maron, Berglind Adalsteinsdottir, Michael Burke, Ragnar Danielsen, Petr Jarolim, Jonathan Seidman, Christine E. Seidman, Carolyn Y Ho, Gunnar Th Gunnarsson
Published 2020-06-01

ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients.

by Spyros Chalkias, Joshua M Gorham, Erica Mazaika, Michael Parfenov, Xin Dang, Steve DePalma, David McKean, Christine E Seidman, Jonathan G Seidman, Igor J Koralnik
Published 2018-01-01

Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue

by Josh Javor, Jourdan K. Ewoldt, Paige E. Cloonan, Anant Chopra, Rebeccah J. Luu, Guillaume Freychet, Mikhail Zhernenkov, Karl Ludwig, Jonathan G. Seidman, Christine E. Seidman, Christopher S. Chen, David J. Bishop
Published 2021-01-01

Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function

by Xin Sun, Swetansu K. Hota, Yu-Qing Zhou, Stefanie Novak, Dario Miguel-Perez, Danos Christodoulou, Christine E. Seidman, J. G. Seidman, Carol C. Gregorio, R. Mark Henkelman, Janet Rossant, Benoit G. Bruneau
Published 2018-01-01

Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia

by Louis A. Saddic, Sarah M. Nicoloro, Olga T. Gupta, Michael P. Czech, Joshua Gorham, Stanton K. Shernan, Christine E. Seidman, Jon G. Seidman, Sary F. Aranki, Simon C. Body, Timothy P. Fitzgibbons, Jochen D. Muehlschlegel
Published 2017-07-01

<italic toggle="yes">LAMP2</italic> Cardiomyopathy: Consequences of Impaired Autophagy in the Heart

by Ronny Alcalai, Michael Arad, Hiroko Wakimoto, Dor Yadin, Joshua Gorham, Libin Wang, Elia Burns, Barry J. Maron, William C. Roberts, Tetsuo Konno, David A. Conner, Antonio R. Perez‐Atayde, Jon G. Seidman, Christine E. Seidman
Published 2021-09-01

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis

by J. Travis Hinson, Anant Chopra, Andre Lowe, Calvin C. Sheng, Rajat M. Gupta, Rajarajan Kuppusamy, John O'Sullivan, Glenn Rowe, Hiroko Wakimoto, Joshua Gorham, Kehan Zhang, Kiran Musunuru, Robert E. Gerszten, Sean M. Wu, Christopher S. Chen, Jonathan G. Seidman, Christine E. Seidman
Published 2016-12-01

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis

by J. Travis Hinson, Anant Chopra, Andre Lowe, Calvin C. Sheng, Rajat M. Gupta, Rajarajan Kuppusamy, John O’Sullivan, Glenn Rowe, Hiroko Wakimoto, Joshua Gorham, Michael A. Burke, Kehan Zhang, Kiran Musunuru, Robert E. Gerszten, Sean M. Wu, Christopher S. Chen, Jonathan G. Seidman, Christine E. Seidman
Published 2017-06-01

Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor

by Yuxuan Guo, Blake D. Jardin, Pingzhu Zhou, Isha Sethi, Brynn N. Akerberg, Christopher N Toepfer, Yulan Ai, Yifei Li, Qing Ma, Silvia Guatimosim, Yongwu Hu, Grigor Varuzhanyan, Nathan J. VanDusen, Donghui Zhang, David C. Chan, Guo-Cheng Yuan, Christine E. Seidman, Jonathan G. Seidman, William T. Pu
Published 2018-09-01

The uptake of family screening in hypertrophic cardiomyopathy and an online video intervention to facilitate family communication

by Stephanie Harris, Allison L. Cirino, Christina W. Carr, Hiwot M. Tafessu, Siddharth Parmar, Jeffrey O. Greenberg, Lara E. Szent‐Gyorgyi, Roya Ghazinouri, Michelle G. Glowny, Kara McNeil, Efthalia F. Kaynor, Catherine Neumann, Christine E. Seidman, Calum A. MacRae, Carolyn Y. Ho, Neal K. Lakdawala
Published 2019-11-01

Genome-wide assessment for genetic variants associated with ventricular dysfunction after primary coronary artery bypass graft surgery.

by Amanda A Fox, Mias Pretorius, Kuang-Yu Liu, Charles D Collard, Tjorvi E Perry, Stanton K Shernan, Philip L De Jager, David A Hafler, Daniel S Herman, Steven R DePalma, Dan M Roden, Jochen D Muehlschlegel, Brian S Donahue, Dawood Darbar, J G Seidman, Simon C Body, Christine E Seidman
Published 2011-01-01

De novo and recessive forms of congenital heart disease have distinct genetic and phenotypic landscapes

by W. Scott Watkins, E. Javier Hernandez, Sergiusz Wesolowski, Brent W. Bisgrove, Ryan T. Sunderland, Edwin Lin, Gordon Lemmon, Bradley L. Demarest, Thomas A. Miller, Daniel Bernstein, Martina Brueckner, Wendy K. Chung, Bruce D. Gelb, Elizabeth Goldmuntz, Jane W. Newburger, Christine E. Seidman, Yufeng Shen, H. Joseph Yost, Mark Yandell, Martin Tristani-Firouzi
Published 2019-10-01

Loss of RNA expression and allele-specific expression associated with congenital heart disease

by David M. McKean, Jason Homsy, Hiroko Wakimoto, Neil Patel, Joshua Gorham, Steven R. DePalma, James S. Ware, Samir Zaidi, Wenji Ma, Nihir Patel, Richard P. Lifton, Wendy K. Chung, Richard Kim, Yufeng Shen, Martina Brueckner, Elizabeth Goldmuntz, Andrew J. Sharp, Christine E. Seidman, Bruce D. Gelb, J. G. Seidman
Published 2016-09-01

The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.

by Ferhaan Ahmad, Sanjay K Banerjee, Michele L Lage, Xueyin N Huang, Stephen H Smith, Samir Saba, Jennifer Rager, David A Conner, Andrzej M Janczewski, Kimimasa Tobita, Joseph P Tinney, Ivan P Moskowitz, Antonio R Perez-Atayde, Bradley B Keller, Michael A Mathier, Sanjeev G Shroff, Christine E Seidman, J G Seidman
Published 2008-07-01

The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy

by Helena M. Viola, PhD, Victoria P.A. Johnstone, PhD, Henrietta Cserne Szappanos, PhD, Tara R. Richman, PhD, Tatiana Tsoutsman, PhD, Aleksandra Filipovska, PhD, Christopher Semsarian, MD, PhD, Jonathan G. Seidman, PhD, Christine E. Seidman, MD, PhD, Livia C. Hool, PhD
Published 2016-01-01