Bacterial Topography of the Healthy Human Lower Respiratory Tract

by Robert P. Dickson, John R. Erb-Downward, Christine M. Freeman, Lisa McCloskey, Nicole R. Falkowski, Gary B. Huffnagle, Jeffrey L. Curtis, Jose C. Clemente
Published 2017-02-01

Changes in the lung microbiome following lung transplantation include the emergence of two distinct Pseudomonas species with distinct clinical associations.

by Robert P Dickson, John R Erb-Downward, Christine M Freeman, Natalie Walker, Brittan S Scales, James M Beck, Fernando J Martinez, Jeffrey L Curtis, Vibha N Lama, Gary B Huffnagle
Published 2014-01-01

Human CD56+ cytotoxic lung lymphocytes kill autologous lung cells in chronic obstructive pulmonary disease.

by Christine M Freeman, Valerie R Stolberg, Sean Crudgington, Fernando J Martinez, MeiLan K Han, Stephen W Chensue, Douglas A Arenberg, Catherine A Meldrum, Lisa McCloskey, Jeffrey L Curtis
Published 2014-01-01

Basal gene expression by lung CD4+ T cells in chronic obstructive pulmonary disease identifies independent molecular correlates of airflow obstruction and emphysema extent.

by Christine M Freeman, Alexandra L McCubbrey, Sean Crudgington, Joshua Nelson, Fernando J Martinez, MeiLan K Han, George R Washko, Stephen W Chensue, Douglas A Arenberg, Catherine A Meldrum, Lisa McCloskey, Jeffrey L Curtis
Published 2014-01-01

Analysis of the lung microbiome in the "healthy" smoker and in COPD.

by John R Erb-Downward, Deborah L Thompson, Meilan K Han, Christine M Freeman, Lisa McCloskey, Lindsay A Schmidt, Vincent B Young, Galen B Toews, Jeffrey L Curtis, Baskaran Sundaram, Fernando J Martinez, Gary B Huffnagle
Published 2011-02-01

Critical Relevance of Stochastic Effects on Low-Bacterial-Biomass 16S rRNA Gene Analysis

by John R. Erb-Downward, Nicole R. Falkowski, Jennifer C. D’Souza, Lisa M. McCloskey, Roderick A. McDonald, Christopher A. Brown, Kerby Shedden, Robert P. Dickson, Christine M. Freeman, Kathleen A. Stringer, Betsy Foxman, Gary B. Huffnagle, Jeffrey L. Curtis, Sara D. Adar
Published 2020-06-01

The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS

by J. Michael Wells, Dongqi Xing, Liliana Viera, Robert M. Burkes, Yixin Wu, Surya P. Bhatt, Mark T. Dransfield, David J. Couper, Wanda O’Neal, Eric A. Hoffman, Amit Gaggar, Igor Barjaktarevic, Jeffrey L. Curtis, Wassim W. Labaki, Mei Lan K. Han, Christine M. Freeman, Nirupama Putcha, Thomas Schlange, J. Edwin Blalock, for the SPIROMICS Investigators
Published 2019-11-01

Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.

by Wei Sun, Katerina Kechris, Sean Jacobson, M Bradley Drummond, Gregory A Hawkins, Jenny Yang, Ting-Huei Chen, Pedro Miguel Quibrera, Wayne Anderson, R Graham Barr, Patricia V Basta, Eugene R Bleecker, Terri Beaty, Richard Casaburi, Peter Castaldi, Michael H Cho, Alejandro Comellas, James D Crapo, Gerard Criner, Dawn Demeo, Stephanie A Christenson, David J Couper, Jeffrey L Curtis, Claire M Doerschuk, Christine M Freeman, Natalia A Gouskova, MeiLan K Han, Nicola A Hanania, Nadia N Hansel, Craig P Hersh, Eric A Hoffman, Robert J Kaner, Richard E Kanner, Eric C Kleerup, Sharon Lutz, Fernando J Martinez, Deborah A Meyers, Stephen P Peters, Elizabeth A Regan, Stephen I Rennard, Mary Beth Scholand, Edwin K Silverman, Prescott G Woodruff, Wanda K O'Neal, Russell P Bowler, SPIROMICS Research Group, COPDGene Investigators
Published 2016-08-01