Editorial: Gene Silencing and Editing Strategies for Neurodegenerative Diseases

by Clévio Nóbrega, Clévio Nóbrega, Clévio Nóbrega, Clévio Nóbrega, Sandro Alves
Published 2018-06-01

Association of FTO polymorphisms with obesity and obesity-related outcomes in Portuguese children.

by David Albuquerque, Clévio Nóbrega, Licínio Manco
Published 2013-01-01

Current Status of Gene Therapy Research in Polyglutamine Spinocerebellar Ataxias

by Ricardo Afonso-Reis, Inês T. Afonso, Clévio Nóbrega
Published 2021-04-01

Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: a Comprehensive Review

by João Miguel Da Conceição Alves-Cruzeiro, Liliana Mendonça, Luis Pereira de Almeida, Luis Pereira de Almeida, Clevio Nobrega, Clevio Nobrega
Published 2016-12-01

Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?

by Adriana Marcelo, Rebekah Koppenol, Luís Pereira de Almeida, Carlos A. Matos, Clévio Nóbrega
Published 2021-06-01

RNA interference mitigates motor and neuropathological deficits in a cerebellar mouse model of Machado-Joseph disease.

by Clévio Nóbrega, Isabel Nascimento-Ferreira, Isabel Onofre, David Albuquerque, Nicole Déglon, Luís Pereira de Almeida
Published 2014-01-01

Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice.

by Clévio Nóbrega, Isabel Nascimento-Ferreira, Isabel Onofre, David Albuquerque, Hirokazu Hirai, Nicole Déglon, Luís Pereira de Almeida
Published 2013-01-01

Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles

by Mariana Conceição, Liliana Mendonça, Clévio Nóbrega, Célia Gomes, Pedro Costa, Hirokazu Hirai, João Nuno Moreira, Maria C. Lima, N. Manjunath, Luís Pereira de Almeida
Published 2016-03-01

Trehalose alleviates the phenotype of Machado–Joseph disease mouse models

by Magda M. Santana, Susana Paixão, Janete Cunha-Santos, Teresa Pereira Silva, Allyson Trevino-Garcia, Laetitia S. Gaspar, Clévio Nóbrega, Rui Jorge Nobre, Cláudia Cavadas, Hagar Greif, Luís Pereira de Almeida
Published 2020-04-01

Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats.

by Lígia Sousa-Ferreira, Manuel Garrido, Isabel Nascimento-Ferreira, Clévio Nobrega, Ana Santos-Carvalho, Ana Rita Alvaro, Joana Rosmaninho-Salgado, Manuella Kaster, Sebastian Kügler, Luís Pereira de Almeida, Claudia Cavadas
Published 2011-01-01

The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington’s disease

by Clévio Nóbrega, André Conceição, Rafael G. Costa, Rebekah Koppenol, Raquel L. Sequeira, Ricardo Nunes, Sara Carmo-Silva, Adriana Marcelo, Carlos A. Matos, Sandrine Betuing, Jocelyne Caboche, Nathalie Cartier, Sandro Alves
Published 2020-04-01