Developing stem cell-based therapies for neural repair

by Clare L Parish, Lachlan eThompson
Published 2013-11-01

Embryonic stem cells go from bench to bedside for Parkinson’s disease

by Clare L. Parish, Lachlan H. Thompson
Published 2021-04-01

An Optimized Protocol for the Generation of Midbrain Dopamine Neurons under Defined Conditions

by Carlos W. Gantner, Agustín Cota-Coronado, Lachlan H. Thompson, Clare L. Parish
Published 2020-09-01

Ischemic Injury Does Not Stimulate Striatal Neuron Replacement Even during Periods of Active Striatal Neurogenesis

by Charlotte M. Ermine, Jordan L. Wright, Davor Stanic, Clare L. Parish, Lachlan H. Thompson
Published 2020-06-01

Biomimetic Materials and Their Utility in Modeling the 3-Dimensional Neural Environment

by Arianna Cembran, Kiara F. Bruggeman, Richard J. Williams, Clare L. Parish, David R. Nisbet
Published 2020-01-01

Focal Ischemic Injury to the Early Neonatal Rat Brain Models Cognitive and Motor Deficits with Associated Histopathological Outcomes Relevant to Human Neonatal Brain Injury

by Brett J. Kagan, Charlotte M. Ermine, Stefano Frausin, Clare L. Parish, Jess Nithianantharajah, Lachlan H. Thompson
Published 2021-04-01

Long-Term Motor Deficit and Diffuse Cortical Atrophy Following Focal Cortical Ischemia in Athymic Rats

by Charlotte M. Ermine, Fahad Somaa, Ting-Yi Wang, Brett J. Kagan, Clare L. Parish, Lachlan H. Thompson
Published 2019-12-01

Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model.

by Jan Tønnesen, Clare L Parish, Andreas T Sørensen, Angelica Andersson, Cecilia Lundberg, Karl Deisseroth, Ernest Arenas, Olle Lindvall, Merab Kokaia
Published 2011-01-01

Neurons derived from human embryonic stem cells extend long–distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation.

by Mark eDenham, Mark eDenham, Clare L Parish, Clare L Parish, Bryan eLeaw, Bryan eLeaw, Jordan eWright, Jordan eWright, Christopher A Reid, Christopher A Reid, Steven ePetrou, Steven ePetrou, Mirella eDottori, Lachlan H Thompson, Lachlan H Thompson
Published 2012-03-01

A fully human inhibitory monoclonal antibody to the Wnt receptor RYK.

by Michael M Halford, Maria L Macheda, Clare L Parish, Elena A Takano, Stephen Fox, Daniel Layton, Edouard Nice, Steven A Stacker
Published 2013-01-01

Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain

by Christopher R. Bye, Vanessa Penna, Isabelle R. de Luzy, Carlos W. Gantner, Cameron P.J. Hunt, Lachlan H. Thompson, Clare L. Parish
Published 2019-11-01

Wnt5a regulates midbrain dopaminergic axon growth and guidance.

by Brette D Blakely, Christopher R Bye, Chathurini V Fernando, Malcolm K Horne, Maria L Macheda, Steven A Stacker, Ernest Arenas, Clare L Parish
Published 2011-03-01

Human stem cells harboring a suicide gene improve the safety and standardisation of neural transplants in Parkinsonian rats

by Isabelle R. de Luzy, Kevin C. L. Law, Niamh Moriarty, Cameron P. J. Hunt, Jennifer C. Durnall, Lachlan H. Thompson, Andras Nagy, Clare L. Parish
Published 2021-05-01

Generation of four iPSC lines from peripheral blood mononuclear cells (PBMCs) of an attention deficit hyperactivity disorder (ADHD) individual and a healthy sibling in an Australia...

by Janette Tong, Kyung Min Lee, Xiaodong Liu, Christian M. Nefzger, Prasidhee Vijayakumar, Ziarih Hawi, Ken C. Pang, Clare L. Parish, Jose M. Polo, Mark A. Bellgrove
Published 2019-01-01

Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy

by Ibrahim Javed, Guotao Peng, Yanting Xing, Tianyu Yu, Mei Zhao, Aleksandr Kakinen, Ava Faridi, Clare L. Parish, Feng Ding, Thomas P. Davis, Pu Chun Ke, Sijie Lin
Published 2019-08-01

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

by Jonathan C. Niclis, Carlos W. Gantner, Cameron P.J. Hunt, Jessica A. Kauhausen, Jennifer C. Durnall, John M. Haynes, Colin W. Pouton, Clare L. Parish, Lachlan H. Thompson
Published 2017-09-01

Motor and behavioral phenotype in conditional mutants with targeted ablation of cortical D1 dopamine receptor-expressing cells

by Luning Jiang, Claire O'Leary, Hyun Ah. Kim, Clare L. Parish, Jim Massalas, John L. Waddington, Michelle E. Ehrlich, Günter Schütz, Ilse Gantois, Andrew J. Lawrence, John Drago
Published 2015-04-01

Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke

by Fahad A. Somaa, Ting-Yi Wang, Jonathan C. Niclis, Kiara F. Bruggeman, Jessica A. Kauhausen, Haoyao Guo, Stuart McDougall, Richard J. Williams, David R. Nisbet, Lachlan H. Thompson, Clare L. Parish
Published 2017-08-01

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

by Diogo Ribeiro, Rocio Laguna Goya, Geeta Ravindran, Romina Vuono, Clare L. Parish, Claire Foldi, Tobias Piroth, Shanzheng Yang, Malin Parmar, Guido Nikkhah, Jens Hjerling-Leffler, Olle Lindvall, Roger A. Barker, Ernest Arenas
Published 2013-01-01

Resolving pathobiological mechanisms relating to Huntington disease: Gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 dopamine receptor cells

by Hyun Ah. Kim, Luning Jiang, Heather Madsen, Clare L. Parish, Jim Massalas, Arthur Smardencas, Claire O'Leary, Ilse Gantois, Colm O'Tuathaigh, John L. Waddington, Michelle E. Ehrlich, Andrew J. Lawrence, John Drago
Published 2014-02-01