Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells

by Lachlan H. Thompson, Anders Björklund
Published 2015-07-01

Embryonic stem cells go from bench to bedside for Parkinson’s disease

by Clare L. Parish, Lachlan H. Thompson
Published 2021-04-01

Histological characterization and quantification of newborn cells in the adult rodent brain

by Charlotte M. Ermine, Carolina A. Chavez, Lachlan H. Thompson
Published 2021-09-01

Novel pluripotent stem cell lines for enriched grafting in Parkinson’s disease

by Agustin Cota-Coronado, Lachlan H Thompson, N Emmanuel Diaz-Martinez
Published 2020-01-01

In vivo gene delivery to proliferating cells in the striatum generated in response to a 6-hydroxydopamine lesion of the nigro-striatal dopamine pathway

by Dwain K. Irvin, Deniz Kirik, Anders Björklund, Lachlan H. Thompson
Published 2008-06-01

An Optimized Protocol for the Generation of Midbrain Dopamine Neurons under Defined Conditions

by Carlos W. Gantner, Agustín Cota-Coronado, Lachlan H. Thompson, Clare L. Parish
Published 2020-09-01

Ischemic Injury Does Not Stimulate Striatal Neuron Replacement Even during Periods of Active Striatal Neurogenesis

by Charlotte M. Ermine, Jordan L. Wright, Davor Stanic, Clare L. Parish, Lachlan H. Thompson
Published 2020-06-01

Unprecedented Potential for Neural Drug Discovery Based on Self-Organizing hiPSC Platforms

by Agustín Cota-Coronado, Jennifer C. Durnall, Néstor Fabián Díaz, Lachlan H. Thompson, N. Emmanuel Díaz-Martínez
Published 2020-03-01

Focal Ischemic Injury to the Early Neonatal Rat Brain Models Cognitive and Motor Deficits with Associated Histopathological Outcomes Relevant to Human Neonatal Brain Injury

by Brett J. Kagan, Charlotte M. Ermine, Stefano Frausin, Clare L. Parish, Jess Nithianantharajah, Lachlan H. Thompson
Published 2021-04-01

Long-Term Motor Deficit and Diffuse Cortical Atrophy Following Focal Cortical Ischemia in Athymic Rats

by Charlotte M. Ermine, Fahad Somaa, Ting-Yi Wang, Brett J. Kagan, Clare L. Parish, Lachlan H. Thompson
Published 2019-12-01

Differential dopamine receptor occupancy underlies L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.

by Gurdal Sahin, Lachlan H Thompson, Sonia Lavisse, Merve Ozgur, Latifa Rbah-Vidal, Frédéric Dollé, Philippe Hantraye, Deniz Kirik
Published 2014-01-01

Neurons derived from human embryonic stem cells extend long–distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation.

by Mark eDenham, Mark eDenham, Clare L Parish, Clare L Parish, Bryan eLeaw, Bryan eLeaw, Jordan eWright, Jordan eWright, Christopher A Reid, Christopher A Reid, Steven ePetrou, Steven ePetrou, Mirella eDottori, Lachlan H Thompson, Lachlan H Thompson
Published 2012-03-01

Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain

by Christopher R. Bye, Vanessa Penna, Isabelle R. de Luzy, Carlos W. Gantner, Cameron P.J. Hunt, Lachlan H. Thompson, Clare L. Parish
Published 2019-11-01

Lentiviral delivery of Meteorin protects striatal neurons against excitotoxicity and reverses motor deficits in the quinolinic acid rat model

by Jesper Roland Jørgensen, Dwaine F. Emerich, Chris Thanos, Lachlan H. Thompson, Malene Torp, Briannan Bintz, Lone Fjord-Larsen, Teit E. Johansen, Lars U. Wahlberg
Published 2011-01-01

Human stem cells harboring a suicide gene improve the safety and standardisation of neural transplants in Parkinsonian rats

by Isabelle R. de Luzy, Kevin C. L. Law, Niamh Moriarty, Cameron P. J. Hunt, Jennifer C. Durnall, Lachlan H. Thompson, Andras Nagy, Clare L. Parish
Published 2021-05-01

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

by Jonathan C. Niclis, Carlos W. Gantner, Cameron P.J. Hunt, Jessica A. Kauhausen, Jennifer C. Durnall, John M. Haynes, Colin W. Pouton, Clare L. Parish, Lachlan H. Thompson
Published 2017-09-01

Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke

by Fahad A. Somaa, Ting-Yi Wang, Jonathan C. Niclis, Kiara F. Bruggeman, Jessica A. Kauhausen, Haoyao Guo, Stuart McDougall, Richard J. Williams, David R. Nisbet, Lachlan H. Thompson, Clare L. Parish
Published 2017-08-01

Longitudinal hippocampal volumetric changes in mice following brain infarction

by Vanessa H. Brait, David K. Wright, Mohsen Nategh, Alexander Oman, Warda T. Syeda, Charlotte M. Ermine, Katrina R. O’Brien, Emilio Werden, Leonid Churilov, Leigh A. Johnston, Lachlan H. Thompson, Jess Nithianantharajah, Katherine A. Jackman, Amy Brodtmann
Published 2021-05-01

Functional characterization of Friedreich ataxia iPS-derived neuronal progenitors and their integration in the adult brain.

by Matthew J Bird, Karina Needham, Ann E Frazier, Jorien van Rooijen, Jessie Leung, Shelley Hough, Mark Denham, Matthew E Thornton, Clare L Parish, Bryony A Nayagam, Martin Pera, David R Thorburn, Lachlan H Thompson, Mirella Dottori
Published 2014-01-01