Heme oxygenase-1 inducer hemin does not inhibit SARS-CoV-2 virus infection

by Sheila Maestro, Karol M. Córdoba, Cristina Olague, Josepmaria Argemi, Matías A. Ávila, Gloria González-Aseguinolaza, Cristian Smerdou, Antonio Fontanellas
Published 2021-05-01

AAV-HDV: An Attractive Platform for the In Vivo Study of HDV Biology and the Mechanism of Disease Pathogenesis

by Sheila Maestro, Nahia Gómez-Echarte, Gracián Camps, Carla Usai, Lester Suárez, África Vales, Cristina Olagüe, Rafael Aldabe, Gloria González-Aseguinolaza
Published 2021-04-01

TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection

by Carla Usai, Sheila Maestro, Gracian Camps, Cristina Olague, Lester Suárez-Amaran, Africa Vales, Tomas Aragon, Mirja Hommel, Rafael Aldabe, Gloria Gonzalez-Aseguinolaza
Published 2020-06-01

IL12-mediated liver inflammation reduces the formation of AAV transcriptionally active forms but has no effect over preexisting AAV transgene expression.

by Irene Gil-Fariña, Marianna Di Scala, Lucia Vanrell, Cristina Olagüe, Africa Vales, Katherine A High, Jesus Prieto, Federico Mingozzi, Gloria Gonzalez-Aseguinolaza
Published 2013-01-01

CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I

by Nerea Zabaleta, Miren Barberia, Cristina Martin-Higueras, Natalia Zapata-Linares, Isabel Betancor, Saray Rodriguez, Rebeca Martinez-Turrillas, Laura Torella, Africa Vales, Cristina Olagüe, Amaia Vilas-Zornoza, Laura Castro-Labrador, David Lara-Astiaso, Felipe Prosper, Eduardo Salido, Gloria Gonzalez-Aseguinolaza, Juan R. Rodriguez-Madoz
Published 2018-12-01