BCL10 – Bridging CARDs to Immune Activation

by Torben Gehring, Thomas Seeholzer, Daniel Krappmann
Published 2018-07-01

YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB

by Gisela Schimmack, Kenji Schorpp, Kerstin Kutzner, Torben Gehring, Jara Kerstin Brenke, Kamyar Hadian, Daniel Krappmann
Published 2017-02-01

BCL10-CARD11 Fusion Mimics an Active CARD11 Seed That Triggers Constitutive BCL10 Oligomerization and Lymphocyte Activation

by Thomas Seeholzer, Susanne Kurz, Florian Schlauderer, Simone Woods, Torben Gehring, Simon Widmann, Katja Lammens, Daniel Krappmann
Published 2018-11-01

Molecular architecture and regulation of BCL10-MALT1 filaments

by Florian Schlauderer, Thomas Seeholzer, Ambroise Desfosses, Torben Gehring, Mike Strauss, Karl-Peter Hopfner, Irina Gutsche, Daniel Krappmann, Katja Lammens
Published 2018-10-01

Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells

by Marc Rosenbaum, Andreas Gewies, Konstanze Pechloff, Christoph Heuser, Thomas Engleitner, Torben Gehring, Lara Hartjes, Sabrina Krebs, Daniel Krappmann, Mark Kriegsmann, Wilko Weichert, Roland Rad, Christian Kurts, Jürgen Ruland
Published 2019-05-01

Regulation of the endosomal SNX27-retromer by OTULIN

by Aurelia Stangl, Paul R. Elliott, Adan Pinto-Fernandez, Sarah Bonham, Luke Harrison, Annalisa Schaub, Kerstin Kutzner, Kirstin Keusekotten, Paul T. Pfluger, Farid El Oualid, Benedikt M. Kessler, David Komander, Daniel Krappmann
Published 2019-09-01

Alternative splicing of MALT1 controls signalling and activation of CD4+ T cells

by Isabel Meininger, Richard A. Griesbach, Desheng Hu, Torben Gehring, Thomas Seeholzer, Arianna Bertossi, Jan Kranich, Andrea Oeckinghaus, Andrea C. Eitelhuber, Ute Greczmiel, Andreas Gewies, Marc Schmidt-Supprian, Jürgen Ruland, Thomas Brocker, Vigo Heissmeyer, Florian Heyd, Daniel Krappmann
Published 2016-04-01

MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells

by Torben Gehring, Tabea Erdmann, Marco Rahm, Carina Graß, Andrew Flatley, Thomas J. O’Neill, Simone Woods, Isabel Meininger, Ozge Karayel, Kerstin Kutzner, Michael Grau, Hisaaki Shinohara, Katja Lammens, Regina Feederle, Stefanie M. Hauck, Georg Lenz, Daniel Krappmann
Published 2019-10-01

Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation

by Jonathan J. Cho, Zhiwei Xu, Upasana Parthasarathy, Theodore T. Drashansky, Eric Y. Helm, Ashley N. Zuniga, Kyle J. Lorentsen, Samira Mansouri, Joshua Y. Cho, Mariola J. Edelmann, Duc M. Duong, Torben Gehring, Thomas Seeholzer, Daniel Krappmann, Mohammad N. Uddin, Danielle Califano, Rejean L. Wang, Lei Jin, Hongmin Li, Dongwen Lv, Daohong Zhou, Liang Zhou, Dorina Avram
Published 2019-02-01