Subcompartmentalisation of proteins in the rhoptries correlates with ordered events of erythrocyte invasion by the blood stage malaria parasite.

by Elizabeth S Zuccala, Alexander M Gout, Chaitali Dekiwadia, Danushka S Marapana, Fiona Angrisano, Lynne Turnbull, David T Riglar, Kelly L Rogers, Cynthia B Whitchurch, Stuart A Ralph, Terence P Speed, Jake Baum
Published 2012-01-01

The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum

by Laure Dumont, Mark B. Richardson, Phillip van der Peet, Danushka S. Marapana, Tony Triglia, Matthew W. A. Dixon, Alan F. Cowman, Spencer J. Williams, Leann Tilley, Malcolm J. McConville, Simon A. Cobbold
Published 2019-12-01

4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation

by Niall D. Geoghegan, Cindy Evelyn, Lachlan W. Whitehead, Michal Pasternak, Phoebe McDonald, Tony Triglia, Danushka S. Marapana, Daryan Kempe, Jennifer K. Thompson, Michael J. Mlodzianoski, Julie Healer, Maté Biro, Alan F. Cowman, Kelly L. Rogers
Published 2021-06-01

Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.

by Brad E Sleebs, Sash Lopaticki, Danushka S Marapana, Matthew T O'Neill, Pravin Rajasekaran, Michelle Gazdik, Svenja Günther, Lachlan W Whitehead, Kym N Lowes, Lea Barfod, Lars Hviid, Philip J Shaw, Anthony N Hodder, Brian J Smith, Alan F Cowman, Justin A Boddey
Published 2014-07-01

Spatial localisation of actin filaments across developmental stages of the malaria parasite.

by Fiona Angrisano, David T Riglar, Angelika Sturm, Jennifer C Volz, Michael J Delves, Elizabeth S Zuccala, Lynne Turnbull, Chaitali Dekiwadia, Maya A Olshina, Danushka S Marapana, Wilson Wong, Vanessa Mollard, Clare H Bradin, Christopher J Tonkin, Peter W Gunning, Stuart A Ralph, Cynthia B Whitchurch, Robert E Sinden, Alan F Cowman, Geoffrey I McFadden, Jake Baum
Published 2012-01-01

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

by Gregory M. LaMonte, Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth, Tilla S. Worgall, Gregory M. Goldgof, Roxanne Mohunlal, T. R. Santha Kumar, Jennifer K. Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M. Williams, Bing Yu Zou, Andrea L. Cheung, Prianka Kumar, Timothy J. Egan, Marcus C. S. Lee, Dionicio Siegel, Alan F. Cowman, David A. Fidock, Elizabeth A. Winzeler
Published 2020-04-01