Ivermectin as a Broad-Spectrum Host-Directed Antiviral: The Real Deal?

by David A. Jans, Kylie M. Wagstaff
Published 2020-09-01

Editorial: Targeted Subcellular Delivery of Anti-cancer Agents

by David A. Jans, Alexander S. Sobolev, Alexander S. Sobolev
Published 2019-01-01

Subversion of Host Cell Mitochondria by RSV to Favor Virus Production is Dependent on Inhibition of Mitochondrial Complex I and ROS Generation

by MengJie Hu, Marie A. Bogoyevitch, David A. Jans
Published 2019-11-01

Application of In Silico and HTS Approaches to Identify Nuclear Import Inhibitors for Venezuelan Equine Encephalitis Virus Capsid Protein: A Case Study

by Sharon Shechter, Sharon Shechter, David R. Thomas, David A. Jans
Published 2020-12-01

Mice Lacking Hbp1 Function Are Viable and Fertile.

by Cassy M Spiller, Dagmar Wilhelm, David A Jans, Josephine Bowles, Peter Koopman
Published 2017-01-01

Nullbasic, a potent anti-HIV tat mutant, induces CRM1-dependent disruption of HIV rev trafficking.

by Min-Hsuan Lin, Haran Sivakumaran, Ann Apolloni, Ting Wei, David A Jans, David Harrich
Published 2012-01-01

Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis

by Kate L. Loveland, Andrew T. Major, Romaly Butler, Julia C. Young, David A. Jans, Yoichi Miyamoto
Published 2015-01-01

Regulated Transport into the Nucleus of Herpesviridae DNA Replication Core Proteins

by Alessandro Ripalti, Arianna Loregian, Simone Avanzi, Daria Camozzi, David A. Jans, Alvisi Gualtiero, Giorgio Palù
Published 2013-09-01

Nuclear import of β-dystroglycan is facilitated by ezrin-mediated cytoskeleton reorganization.

by Alejandra Vásquez-Limeta, Kylie M Wagstaff, Arturo Ortega, Dorothy H Crouch, David A Jans, Bulmaro Cisneros
Published 2014-01-01

Nuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain.

by Caitlin L Rowe, Kylie M Wagstaff, Sibil Oksayan, Dominic J Glover, David A Jans, Gregory W Moseley
Published 2016-01-01

RK-33 Is a Broad-Spectrum Antiviral Agent That Targets DEAD-Box RNA Helicase DDX3X

by Sundy N. Y. Yang, Sarah C. Atkinson, Michelle D. Audsley, Steven M. Heaton, David A. Jans, Natalie A. Borg
Published 2020-01-01

Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity

by Steven M. Heaton, Sarah C. Atkinson, Melissa N. Sweeney, Sundy N. Y. Yang, David A. Jans, Natalie A. Borg
Published 2019-09-01

Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness

by Elizabeth Hinde, Elvis Pandžić, Zhengmin Yang, Ivan H. W. Ng, David A. Jans, Marie A. Bogoyevitch, Enrico Gratton, Katharina Gaus
Published 2016-03-01

Rhinovirus 3C protease facilitates specific nucleoporin cleavage and mislocalisation of nuclear proteins in infected host cells.

by Erin J Walker, Parisa Younessi, Alex J Fulcher, Robert McCuaig, Belinda J Thomas, Philip G Bardin, David A Jans, Reena Ghildyal
Published 2013-01-01

Adenovirus Terminal Protein Contains a Bipartite Nuclear Localisation Signal Essential for Its Import into the Nucleus

by Hareth A. Al-Wassiti, David R. Thomas, Kylie M. Wagstaff, Stewart A. Fabb, David A. Jans, Angus P. Johnston, Colin W. Pouton
Published 2021-03-01

Dengue Non-structural Protein 5 Polymerase Complexes With Promyelocytic Leukemia Protein (PML) Isoforms III and IV to Disrupt PML-Nuclear Bodies in Infected Cells

by Federico Giovannoni, Federico Giovannoni, María Fatima Ladelfa, María Fatima Ladelfa, Martin Monte, Martin Monte, David A. Jans, Peter Hemmerich, Cybele García, Cybele García
Published 2019-08-01

Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells.

by Lindsay Lundberg, Chelsea Pinkham, Cynthia de la Fuente, Ashwini Brahms, Nazly Shafagati, Kylie M Wagstaff, David A Jans, Sharon Tamir, Kylene Kehn-Hall
Published 2016-11-01

The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways

by Sunyuan Zhang, Nicholas A. Williamson, Lisa Duvick, Alexander Lee, Harry T. Orr, Austin Korlin-Downs, Praseuth Yang, Yee-Foong Mok, David A. Jans, Marie A. Bogoyevitch
Published 2020-07-01

Phenotypic Divergence of P Proteins of Australian Bat Lyssavirus Lineages Circulating in Microbats and Flying Foxes

by Celine Deffrasnes, Meng-Xiao Luo, Linda Wiltzer-Bach, Cassandra T. David, Kim G. Lieu, Lin-Fa Wang, David A. Jans, Glenn A. Marsh, Gregory W. Moseley
Published 2021-05-01

Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer

by Sundy N. Y. Yang, Sarah C. Atkinson, Johanna E. Fraser, Chunxiao Wang, Belinda Maher, Noelia Roman, Jade K. Forwood, Kylie M. Wagstaff, Natalie A. Borg, David A. Jans
Published 2019-03-01