Akt and mTOR in B cell activation and differentiation

by David A. Fruman, Jose J. Limon
Published 2012-08-01

Effects of novel isoform-selective phosphoinositide 3-kinase inhibitors on natural killer cell function.

by Sung Su Yea, Lomon So, Sharmila Mallya, Jongdae Lee, Kamalakannan Rajasekaran, Subramaniam Malarkannan, David A Fruman
Published 2014-01-01

Resistance to mTOR kinase inhibitors in lymphoma cells lacking 4EBP1.

by Sharmila Mallya, Briana A Fitch, J Scott Lee, Lomon So, Matthew R Janes, David A Fruman
Published 2014-01-01

Reduced eIF4E function impairs B-cell leukemia without altering normal B-lymphocyte function

by Honyin Chiu, Roberta Buono, Leandra V. Jackson, Lee-or Herzog, Sharmila Mallya, Crystal S. Conn, Davide Ruggero, David A. Fruman
Published 2021-07-01

Efficacy of a Novel Bi-Steric mTORC1 Inhibitor in Models of B-Cell Acute Lymphoblastic Leukemia

by Bianca J. Lee, Sharmila Mallya, Nuntana Dinglasan, Amos Fung, Tram Nguyen, Lee-or Herzog, Joshua Thao, Edward G. Lorenzana, David Wildes, Mallika Singh, Jacqueline A. M. Smith, David A. Fruman
Published 2021-08-01

The Selective Phosphoinoside-3-Kinase p110δ Inhibitor IPI-3063 Potently Suppresses B Cell Survival, Proliferation, and Differentiation

by Honyin Chiu, Sharmila Mallya, Phuongthao Nguyen, Annie Mai, Leandra V. Jackson, David G. Winkler, Jonathan P. DiNitto, Erin E. Brophy, Karen McGovern, Jeffery L. Kutok, David A. Fruman
Published 2017-06-01

Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth

by Mari B. Ishak Gabra, Ying Yang, Haiqing Li, Parijat Senapati, Eric A. Hanse, Xazmin H. Lowman, Thai Q. Tran, Lishi Zhang, Linda T. Doan, Xiangdong Xu, Dustin E. Schones, David A. Fruman, Mei Kong
Published 2020-07-01

A cross-institutional analysis of the effects of broadening trainee professional development on research productivity.

by Patrick D Brandt, Susi Sturzenegger Varvayanis, Tracey Baas, Amanda F Bolgioni, Janet Alder, Kimberly A Petrie, Isabel Dominguez, Abigail M Brown, C Abigail Stayart, Harinder Singh, Audra Van Wart, Christine S Chow, Ambika Mathur, Barbara M Schreiber, David A Fruman, Brent Bowden, Christopher A Wiesen, Yvonne M Golightly, Chris E Holmquist, Daniel Arneman, Joshua D Hall, Linda E Hyman, Kathleen L Gould, Roger Chalkley, Patrick J Brennwald, Rebekah L Layton
Published 2021-07-01