Liver Biopsy Shines a Light on COVID-19-Related Liver Injury

by David E. Kleiner, MD, PHD
Published 2021-01-01

Compartmental analysis of plasma and liver n-3 essential fatty acids in alcohol-dependent men during withdrawal

by Robert J. Pawlosky, Joseph R. Hibbeln, David Herion, David E. Kleiner, Norman Salem, Jr.
Published 2009-01-01

Liver regeneration signature in hepatitis B virus (HBV)-associated acute liver failure identified by gene expression profiling.

by Oriel Nissim, Marta Melis, Giacomo Diaz, David E Kleiner, Ashley Tice, Giovanni Fantola, Fausto Zamboni, Lopa Mishra, Patrizia Farci
Published 2012-01-01

Pulmonary tumor thrombotic microangiopathy and pulmonary veno-occlusive disease in a woman with cervical cancer treated with cediranib and durvalumab

by Dante A. Suffredini, Jung-Min Lee, Cody J. Peer, Drew Pratt, David E. Kleiner, Jason M. Elinoff, Michael A. Solomon
Published 2018-07-01

Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B

by Yao Li, Yuchen Xia, Xiaoming Cheng, David E. Kleiner, Stephen M. Hewitt, Julia Sproch, Tong Li, Hui Zhuang, T. Jake Liang
Published 2019-04-01

Mesothelin as a Potential Therapeutic Target in Human Cholangiocarcinoma

by Liping Yu, Mingqian Feng, Heungnam Kim, Yen Phung, David E. Kleiner, Gregory J. Gores, Min Qian, Xin Wei Wang, Mitchell Ho
Published 2010-01-01

NASH and cryptogenic cirrhosis: A histological analysis†† Financial Support/Grants: This research supported in part by the Intramural Research Program of the NIH, National Cancer I...

by Stephen H. Caldwell, Vanessa D. Lee, David E. Kleiner, Abdullah M.S. Al-Osaimi, Curtis K. Argo, Patrick G. Northup, Carl L. Berg
Published 2009-10-01

A spectrum of severe familial liver disorders associate with telomerase mutations.

by Rodrigo T Calado, Joshua A Regal, David E Kleiner, David S Schrump, Nathan R Peterson, Veronica Pons, Stephen J Chanock, Peter M Lansdorp, Neal S Young
Published 2009-11-01

Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series

by Amy V. Rapkiewicz, Xingchen Mai, Steven E. Carsons, Stefania Pittaluga, David E. Kleiner, Jeffrey S. Berger, Sarun Thomas, Nicole M. Adler, David M. Charytan, Billel Gasmi, Judith S. Hochman, Harmony R. Reynolds
Published 2020-07-01

Clinical and Histopathologic Features of Interstitial Lung Disease in Erdheim–Chester Disease

by Sara G. Haroutunian, Kevin J. O’Brien, Juvianee I. Estrada-Veras, Jianhua Yao, Louisa C. Boyd, Kavya Mathur, William A. Gahl, S. Mojdeh Mirmomen, Ashkan A. Malayeri, David E. Kleiner, Elaine S. Jaffe, Bernadette R. Gochuico
Published 2018-08-01

A novel bacterium associated with lymphadenitis in a patient with chronic granulomatous disease.

by David E Greenberg, Li Ding, Adrian M Zelazny, Frida Stock, Alexandra Wong, Victoria L Anderson, Georgina Miller, David E Kleiner, Allan R Tenorio, Lauren Brinster, David W Dorward, Patrick R Murray, Steven M Holland
Published 2006-04-01

Analysis of TP53 aflatoxin signature mutation in hepatocellular carcinomas from Guatemala: A cross‐sectional study (2016‐2017)

by Christian S. Alvarez, Jeremy Ortiz, Giovanna Bendfeldt‐Avila, Yi Xie, Mingyi Wang, Dongjing Wu, Herbert Higson, Elisa Lee, Kedest Teshome, Joaquin Barnoya, David E. Kleiner, John D. Groopman, Roberto Orozco, Katherine A. McGlynn, Eduardo Gharzouzi, Michael Dean
Published 2020-06-01

Effects of tesamorelin on hepatic transcriptomic signatures in HIV-associated NAFLD

by Lindsay T. Fourman, James M. Billingsley, George Agyapong, Shannan J. Ho Sui, Meghan N. Feldpausch, Julia Purdy, Isabel Zheng, Chelsea S. Pan, Kathleen E. Corey, Martin Torriani, David E. Kleiner, Colleen M. Hadigan, Takara L. Stanley, Raymond T. Chung, Steven K. Grinspoon
Published 2020-08-01

Delineating tesamorelin response pathways in HIV-associated NAFLD using a targeted proteomic and transcriptomic approach

by Lindsay T. Fourman, Takara L. Stanley, James M. Billingsley, Shannan J. Ho Sui, Meghan N. Feldpausch, Autumn Boutin, Isabel Zheng, Colin M. McClure, Kathleen E. Corey, Martin Torriani, David E. Kleiner, Colleen M. Hadigan, Raymond T. Chung, Steven K. Grinspoon
Published 2021-05-01

Telomere Length and Survival of Patients with Hepatocellular Carcinoma in the United States.

by Baiyu Yang, Fatma M Shebl, Lawrence R Sternberg, Andrew C Warner, David E Kleiner, Daniel C Edelman, Allison Gomez, Casey L Dagnall, Belynda D Hicks, Sean F Altekruse, Brenda Y Hernandez, Charles F Lynch, Paul S Meltzer, Katherine A McGlynn
Published 2016-01-01

Spleen and Liver Volumetrics as Surrogate Markers of Hepatic Venous Pressure Gradient in Patients With Noncirrhotic Portal Hypertension

by Ohad Etzion, Varun Takyar, Victor Novack, Ahmed M. Gharib, Raissa Canales, Akeem Adebogun, Eric Matsumoto, Jason L. Eccleston, David E. Kleiner, Sergio D. Rosenzweig, Meral Gunay‐Aygun, Gulbu Uzel, Ivan Fuss, Richard Childs, Steven M. Holland, Elliot B. Levy, T. Jake Liang, Theo Heller, Christopher Koh
Published 2018-08-01

Magnetic Resonance Elastography Shear Wave Velocity Correlates with Liver Fibrosis and Hepatic Venous Pressure Gradient in Adults with Advanced Liver Disease

by Ahmed M. Gharib, Ma Ai Thanda Han, Eric G. Meissner, David E. Kleiner, Xiongce Zhao, Mary McLaughlin, Lindsay Matthews, Bisharah Rizvi, Khaled Z. Abd-Elmoniem, Ralph Sinkus, Elliot Levy, Christopher Koh, Robert P. Myers, G. Mani Subramanian, Shyam Kottilil, Theo Heller, Joseph A. Kovacs, Caryn G. Morse
Published 2017-01-01

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

by Nitin Roper, Shaojian Gao, Tapan K. Maity, A. Rouf Banday, Xu Zhang, Abhilash Venugopalan, Constance M. Cultraro, Rajesh Patidar, Sivasish Sindiri, Anna-Leigh Brown, Alexander Goncearenco, Anna R. Panchenko, Romi Biswas, Anish Thomas, Arun Rajan, Corey A. Carter, David E. Kleiner, Stephen M. Hewitt, Javed Khan, Ludmila Prokunina-Olsson, Udayan Guha
Published 2019-03-01

Characterization of Gut Microbiome in Liver Transplant Recipients With Nonalcoholic Steatohepatitis

by Sanjaya K. Satapathy, MD, DM, MS (Epi), Pratik Banerjee, PhD, Joseph F. Pierre, PhD, Daleniece Higgins, PhD, Soma Dutta, MD, Rajiv Heda, BS, Sabrina D. Khan, BA, Vamsee K. Mupparaju, MD, Valeria Mas, , PhD, Satheesh Nair, MD, James D. Eason, MD, David E. Kleiner, MD, Daniel G. Maluf, MD
Published 2020-12-01

Vitamin E treatment in NAFLD patients demonstrates that oxidative stress drives steatosis through upregulation of de-novo lipogenesis

by Maren C. Podszun, Ahmad S. Alawad, Shilpa Lingala, Nevitt Morris, Wen-Chun A. Huang, Shanna Yang, Megan Schoenfeld, Adam Rolt, Ronald Ouwerkerk, Kristin Valdez, Regina Umarova, Yanling Ma, Syeda Zaheen Fatima, Dennis D. Lin, Lakshmi S. Mahajan, Niharika Samala, Pierre-Christian Violet, Mark Levine, Robert Shamburek, Ahmed M. Gharib, David E. Kleiner, H. Martin Garraffo, Hongyi Cai, Peter J. Walter, Yaron Rotman
Published 2020-10-01