SIRT2 knockout exacerbates insulin resistance in high fat-fed mice.

by Louise Lantier, Ashley S Williams, Curtis C Hughey, Deanna P Bracy, Freyja D James, Muhammad A Ansari, David Gius, David H Wasserman
Published 2018-01-01

Sirt3, Mitochondrial ROS, Ageing, and Carcinogenesis

by David Gius, Hyun-Seok Kim, Yong I. Cha, Ozkan Ozden, J. Daniel Pennington, Seong-Hoon Park, Nukhet Aykin-Burns, Douglas R. Spitz, Haiyan Jiang
Published 2011-09-01

SIRT3 Overexpression Ameliorates Asbestos-Induced Pulmonary Fibrosis, mt-DNA Damage, and Lung Fibrogenic Monocyte Recruitment

by Paul Cheresh, Seok-Jo Kim, Renea Jablonski, Satoshi Watanabe, Ziyan Lu, Monica Chi, Kathryn A. Helmin, David Gius, G. R. Scott Budinger, David W. Kamp
Published 2021-06-01

Ionizing radiation-induced oxidative stress alters miRNA expression.

by Nicole L Simone, Benjamin P Soule, David Ly, Anthony D Saleh, Jason E Savage, William Degraff, John Cook, Curtis C Harris, David Gius, James B Mitchell
Published 2009-07-01

SIRT3 interacts with the daf-16 homolog FOXO3a in the Mitochondria, as well as increases FOXO3a Dependent Gene expression

by Kristi Muldoon Jacobs, J. Daniel Pennington, Kheem S. Bisht, Nukhet Aykin-Burns, Hyun-Seok Kim, Mark Mishra, Lunching Sun, Phuongmai Nguyen, Bong-Hyun Ahn, Jaime Leclerc, Chu-Xia Deng, Douglas R. Spitz, David Gius
Published 2008-01-01

Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter

by Yueming Zhu, Xianghui Zou, Angela E. Dean, Joseph O’ Brien, Yucheng Gao, Elizabeth L. Tran, Seong-Hoon Park, Guoxiang Liu, Matthew B. Kieffer, Haiyan Jiang, Melissa E. Stauffer, Robert Hart, Songhua Quan, Karla J. F. Satchell, Nobuo Horikoshi, Marcelo Bonini, David Gius
Published 2019-06-01

Genotype and Tumor Locus Determine Expression Profile of Pseudohypoxic Pheochromocytomas and Paragangliomas

by Uma Shankavaram, Stephanie M.J. Fliedner, Abdel G. Elkahloun, Jenifer J. Barb, Peter J. Munson, Thanh T. Huynh, Joey C. Matro, Hana Turkova, W. Marston Linehan, Henri J. Timmers, Arthur S. Tischler, James F. Powers, Ronald de Krijger, Bora E. Baysal, Martina Takacova, Silvia Pastorekova, David Gius, Hendrik Lehnert, Kevin Camphausen, Karel Pacak
Published 2013-04-01

ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA

by Hui Zhang, PamelaSara E. Head, Waaqo Daddacha, Seong-Hoon Park, Xingzhe Li, Yunfeng Pan, Matthew Z. Madden, Duc M. Duong, Maohua Xie, Bing Yu, Matthew D. Warren, Elaine A. Liu, Vishal R. Dhere, Chunyang Li, Ivan Pradilla, Mylin A. Torres, Ya Wang, William S. Dynan, Paul W. Doetsch, Xingming Deng, Nicholas T. Seyfried, David Gius, David S. Yu
Published 2016-02-01