Ntrk1 mutation co-segregating with bipolar disorder and inherited kidney disease in a multiplex family causes defects in neuronal growth and depression-like behavior in mice

by Kazuo Nakajima, Alannah Miranda, David W. Craig, Tatyana Shekhtman, Stanislav Kmoch, Anthony Bleyer, Szabolcs Szelinger, Tadafumi Kato, John R. Kelsoe
Published 2020-11-01

Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms.

by Manuel Comabella, David W Craig, Montse Camiña-Tato, Carlos Morcillo, Cristina Lopez, Arcadi Navarro, Jordi Rio, BiomarkerMS Study Group, Xavier Montalban, Roland Martin
Published 2008-01-01

Small RNA Deep Sequencing Identifies a Unique miRNA Signature Released in Serum Exosomes in a Mouse Model of Sjögren's Syndrome

by Shruti Singh Kakan, Srikanth R. Janga, Benjamin Cooperman, David W. Craig, Maria C. Edman, Curtis T. Okamoto, Sarah F. Hamm-Alvarez, Sarah F. Hamm-Alvarez
Published 2020-07-01

Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays.

by Nils Homer, Szabolcs Szelinger, Margot Redman, David Duggan, Waibhav Tembe, Jill Muehling, John V Pearson, Dietrich A Stephan, Stanley F Nelson, David W Craig
Published 2008-08-01

A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy.

by Glen J Weiss, Sara A Byron, Jessica Aldrich, Ashish Sangal, Heather Barilla, Jeffrey A Kiefer, John D Carpten, David W Craig, Timothy G Whitsett
Published 2017-01-01

Characterization of X chromosome inactivation using integrated analysis of whole-exome and mRNA sequencing.

by Szabolcs Szelinger, Ivana Malenica, Jason J Corneveaux, Ashley L Siniard, Ahmet A Kurdoglu, Keri M Ramsey, Isabelle Schrauwen, Jeffrey M Trent, Vinodh Narayanan, Matthew J Huentelman, David W Craig
Published 2014-01-01

Genomic Copy Number Analysis in Alzheimer's Disease and Mild Cognitive Impairment: An ADNI Study

by Shanker Swaminathan, Sungeun Kim, Li Shen, Shannon L. Risacher, Tatiana Foroud, Nathan Pankratz, Steven G. Potkin, Matthew J. Huentelman, David W. Craig, Michael W. Weiner, Andrew J. Saykin, The Alzheimer's Disease Neuroimaging Initiative (ADNI)
Published 2011-01-01

A population-specific reference panel empowers genetic studies of Anabaptist populations

by Liping Hou, Rachel L. Kember, Jared C. Roach, Jeffrey R. O’Connell, David W. Craig, Maja Bucan, William K. Scott, Margaret Pericak-Vance, Jonathan L. Haines, Michael H. Crawford, Alan R. Shuldiner, Francis J. McMahon
Published 2017-07-01

A Frame-Shift Mutation in CAV1 Is Associated with a Severe Neonatal Progeroid and Lipodystrophy Syndrome.

by Isabelle Schrauwen, Szabolcs Szelinger, Ashley L Siniard, Ahmet Kurdoglu, Jason J Corneveaux, Ivana Malenica, Ryan Richholt, Guy Van Camp, Matt De Both, Shanker Swaminathan, Mari Turk, Keri Ramsey, David W Craig, Vinodh Narayanan, Matthew J Huentelman
Published 2015-01-01

Autism and increased paternal age related changes in global levels of gene expression regulation.

by Mark D Alter, Rutwik Kharkar, Keri E Ramsey, David W Craig, Raun D Melmed, Theresa A Grebe, R Curtis Bay, Sharman Ober-Reynolds, Janet Kirwan, Josh J Jones, J Blake Turner, Rene Hen, Dietrich A Stephan
Published 2011-02-01

Paired tumor and normal whole genome sequencing of metastatic olfactory neuroblastoma.

by Glen J Weiss, Winnie S Liang, Tyler Izatt, Shilpi Arora, Irene Cherni, Robert N Raju, Galen Hostetter, Ahmet Kurdoglu, Alexis Christoforides, Shripad Sinari, Angela S Baker, Raghu Metpally, Waibhav D Tembe, Lori Phillips, Daniel D Von Hoff, David W Craig, John D Carpten
Published 2012-01-01

A method to reduce ancestry related germline false positives in tumor only somatic variant calling

by Rebecca F. Halperin, John D. Carpten, Zarko Manojlovic, Jessica Aldrich, Jonathan Keats, Sara Byron, Winnie S. Liang, Megan Russell, Daniel Enriquez, Ana Claasen, Irene Cherni, Baffour Awuah, Joseph Oppong, Max S. Wicha, Lisa A. Newman, Evelyn Jaigge, Seungchan Kim, David W. Craig
Published 2017-10-01

A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.

by Glen J Weiss, Winnie S Liang, Michael J Demeure, Jeff A Kiefer, Galen Hostetter, Tyler Izatt, Shripad Sinari, Alexis Christoforides, Jessica Aldrich, Ahmet Kurdoglu, Lori Phillips, Hollie Benson, Rebecca Reiman, Angela Baker, Vickie Marsh, Daniel D Von Hoff, John D Carpten, David W Craig
Published 2013-01-01

Case Report: Novel mutations in TBC1D24 are associated with autosomal dominant tonic-clonic and myoclonic epilepsy and recessive Parkinsonism, psychosis, and intellectual disabilit...

by Erika Banuelos, Keri Ramsey, Newell Belnap, Malavika Krishnan, Chris Balak, Szabolcs Szelinger, Ashley L. Siniard, Megan Russell, Ryan Richholt, Matt De Both, Ignazio Piras, Marcus Naymik, Ana M. Claasen, Sampathkumar Rangasamy, Matthew J. Huentelman, David W. Craig, Philippe M. Campeau, Vinodh Narayanan, Isabelle Schrauwen
Published 2017-04-01

Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 rearrangements.

by Jan B Egan, Michael T Barrett, Mia D Champion, Sumit Middha, Elizabeth Lenkiewicz, Lisa Evers, Princy Francis, Jessica Schmidt, Chang-Xin Shi, Scott Van Wier, Sandra Badar, Gregory Ahmann, K Martin Kortuem, Nicole J Boczek, Rafael Fonseca, David W Craig, John D Carpten, Mitesh J Borad, A Keith Stewart
Published 2014-01-01

Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing.

by Winnie S Liang, David W Craig, John Carpten, Mitesh J Borad, Michael J Demeure, Glen J Weiss, Tyler Izatt, Shripad Sinari, Alexis Christoforides, Jessica Aldrich, Ahmet Kurdoglu, Michael Barrett, Lori Phillips, Hollie Benson, Waibhav Tembe, Esteban Braggio, Jeffrey A Kiefer, Christophe Legendre, Richard Posner, Galen H Hostetter, Angela Baker, Jan B Egan, Haiyong Han, Douglas Lake, Edward C Stites, Ramesh K Ramanathan, Rafael Fonseca, A Keith Stewart, Daniel Von Hoff
Published 2012-01-01

Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.

by Erin N Smith, Daniel L Koller, Corrie Panganiban, Szabolcs Szelinger, Peng Zhang, Judith A Badner, Thomas B Barrett, Wade H Berrettini, Cinnamon S Bloss, William Byerley, William Coryell, Howard J Edenberg, Tatiana Foroud, Elliot S Gershon, Tiffany A Greenwood, Yiran Guo, Maria Hipolito, Brendan J Keating, William B Lawson, Chunyu Liu, Pamela B Mahon, Melvin G McInnis, Francis J McMahon, Rebecca McKinney, Sarah S Murray, Caroline M Nievergelt, John I Nurnberger, Evaristus A Nwulia, James B Potash, John Rice, Thomas G Schulze, William A Scheftner, Paul D Shilling, Peter P Zandi, Sebastian Zöllner, David W Craig, Nicholas J Schork, John R Kelsoe
Published 2011-06-01

Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

by Mitesh J. Borad, Jan B. Egan, Rachel M. Condjella, Winnie S. Liang, Rafael Fonseca, Nicole R. Ritacca, Ann E. McCullough, Michael T. Barrett, Katherine S. Hunt, Mia D. Champion, Maitray D. Patel, Scott W. Young, Alvin C. Silva, Thai H. Ho, Thorvardur R. Halfdanarson, Robert R. McWilliams, Konstantinos N. Lazaridis, Ramesh K. Ramanathan, Angela Baker, Jessica Aldrich, Ahmet Kurdoglu, Tyler Izatt, Alexis Christoforides, Irene Cherni, Sara Nasser, Rebecca Reiman, Lori Cuyugan, Jacquelyn McDonald, Jonathan Adkins, Stephen D. Mastrian, Riccardo Valdez, Dawn E. Jaroszewski, Daniel D. Von Hoff, David W. Craig, A. Keith Stewart, John D. Carpten, Alan H. Bryce
Published 2016-12-01

Identifying treatment options for BRAFV600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial.

by Patricia M LoRusso, Aleksandar Sekulic, Jeffrey A Sosman, Winnie S Liang, John Carpten, David W Craig, David B Solit, Alan H Bryce, Jeffrey A Kiefer, Jessica Aldrich, Sara Nasser, Rebecca Halperin, Sara A Byron, Mary Jo Pilat, Scott A Boerner, Diane Durecki, William P D Hendricks, Daniel Enriquez, Tyler Izatt, Jonathan Keats, Christophe Legendre, Svetomir N Markovic, Amy Weise, Fatima Naveed, Jessica Schmidt, Gargi D Basu, Shobana Sekar, Jonathan Adkins, Erica Tassone, Karthigayini Sivaprakasam, Victoria Zismann, Valerie S Calvert, Emanuel F Petricoin, Leslie Anne Fecher, Christopher Lao, J Paul Eder, Nicholas J Vogelzang, Jane Perlmutter, Mark Gorman, Barbara Manica, Lisa Fox, Nicholas Schork, Daniel Zelterman, Michelle DeVeaux, Richard W Joseph, C Lance Cowey, Jeffrey M Trent
Published 2021-01-01

Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma.

by Mitesh J Borad, Mia D Champion, Jan B Egan, Winnie S Liang, Rafael Fonseca, Alan H Bryce, Ann E McCullough, Michael T Barrett, Katherine Hunt, Maitray D Patel, Scott W Young, Joseph M Collins, Alvin C Silva, Rachel M Condjella, Matthew Block, Robert R McWilliams, Konstantinos N Lazaridis, Eric W Klee, Keith C Bible, Pamela Harris, Gavin R Oliver, Jaysheel D Bhavsar, Asha A Nair, Sumit Middha, Yan Asmann, Jean-Pierre Kocher, Kimberly Schahl, Benjamin R Kipp, Emily G Barr Fritcher, Angela Baker, Jessica Aldrich, Ahmet Kurdoglu, Tyler Izatt, Alexis Christoforides, Irene Cherni, Sara Nasser, Rebecca Reiman, Lori Phillips, Jackie McDonald, Jonathan Adkins, Stephen D Mastrian, Pamela Placek, Aprill T Watanabe, Janine Lobello, Haiyong Han, Daniel Von Hoff, David W Craig, A Keith Stewart, John D Carpten
Published 2014-02-01