Systematic evaluation of cancer‐specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts

by Zhuqing Shi, Hongjie Yu, Yishuo Wu, Xiaoling Lin, Quanwa Bao, Haifei Jia, Chelsea Perschon, David Duggan, Brian T. Helfand, Siqun L. Zheng, Jianfeng Xu
Published 2019-06-01

Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays.

by Nils Homer, Szabolcs Szelinger, Margot Redman, David Duggan, Waibhav Tembe, Jill Muehling, John V Pearson, Dietrich A Stephan, Stanley F Nelson, David W Craig
Published 2008-08-01

Genome-Wide Association Study of Serum Selenium Concentrations

by Ulrike Peters, James R. Marshall, Charles B. Eaton, Stephen J. Chanock, Yan Liu, Carolyn Hutter, David Duggan, Xiaoling Song, Tabitha Harrison, Irena B. King, Stefan Stürup, Jian Gong, Li Hsu
Published 2013-05-01

Recombination and its impact on the genome of the haplodiploid parasitoid wasp Nasonia.

by Oliver Niehuis, Joshua D Gibson, Michael S Rosenberg, Bart A Pannebakker, Tosca Koevoets, Andrea K Judson, Christopher A Desjardins, Kathleen Kennedy, David Duggan, Leo W Beukeboom, Louis van de Zande, David M Shuker, John H Werren, Jürgen Gadau
Published 2010-01-01

Pleiotropy of cancer susceptibility variants on the risk of non-Hodgkin lymphoma: the PAGE consortium.

by Unhee Lim, Jonathan M Kocarnik, William S Bush, Tara C Matise, Christian Caberto, Sungshim Lani Park, Christopher S Carlson, Ewa Deelman, David Duggan, Megan Fesinmeyer, Christopher A Haiman, Brian E Henderson, Lucia A Hindorff, Laurence N Kolonel, Ulrike Peters, Daniel O Stram, Maarit Tiirikainen, Lynne R Wilkens, Chunyuan Wu, Charles Kooperberg, Loïc Le Marchand
Published 2014-01-01

Fine-mapping and initial characterization of QT interval loci in African Americans.

by Christy L Avery, Praveen Sethupathy, Steven Buyske, Qianchuan He, Dan-Yu Lin, Dan E Arking, Cara L Carty, David Duggan, Megan D Fesinmeyer, Lucia A Hindorff, Janina M Jeff, Liviu Klein, Kristen K Patton, Ulrike Peters, Ralph V Shohet, Nona Sotoodehnia, Alicia M Young, Charles Kooperberg, Christopher A Haiman, Karen L Mohlke, Eric A Whitsel, Kari E North
Published 2012-01-01

Pleiotropic and sex-specific effects of cancer GWAS SNPs on melanoma risk in the population architecture using genomics and epidemiology (PAGE) study.

by Jonathan M Kocarnik, S Lani Park, Jiali Han, Logan Dumitrescu, Iona Cheng, Lynne R Wilkens, Fredrick R Schumacher, Laurence Kolonel, Chris S Carlson, Dana C Crawford, Robert J Goodloe, Holli H Dilks, Paxton Baker, Danielle Richardson, Tara C Matise, José Luis Ambite, Fengju Song, Abrar A Qureshi, Mingfeng Zhang, David Duggan, Carolyn Hutter, Lucia Hindorff, William S Bush, Charles Kooperberg, Loic Le Marchand, Ulrike Peters
Published 2015-01-01

Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study.

by Steven Buyske, Ying Wu, Cara L Carty, Iona Cheng, Themistocles L Assimes, Logan Dumitrescu, Lucia A Hindorff, Sabrina Mitchell, Jose Luis Ambite, Eric Boerwinkle, Petra Buzkova, Chris S Carlson, Barbara Cochran, David Duggan, Charles B Eaton, Megan D Fesinmeyer, Nora Franceschini, Jeffrey Haessler, Nancy Jenny, Hyun Min Kang, Charles Kooperberg, Yi Lin, Loic Le Marchand, Tara C Matise, Jennifer G Robinson, Carlos Rodriguez, Fredrick R Schumacher, Benjamin F Voight, Alicia Young, Teri A Manolio, Karen L Mohlke, Christopher A Haiman, Ulrike Peters, Dana C Crawford, Kari E North
Published 2012-01-01

Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants.

by Mengmeng Du, Shuo Jiao, Stephanie A Bien, Manish Gala, Goncalo Abecasis, Stephane Bezieau, Hermann Brenner, Katja Butterbach, Bette J Caan, Christopher S Carlson, Graham Casey, Jenny Chang-Claude, David V Conti, Keith R Curtis, David Duggan, Steven Gallinger, Robert W Haile, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, John L Hopper, Thomas J Hudson, Mark A Jenkins, Sébastien Küry, Loic Le Marchand, Suzanne M Leal, Polly A Newcomb, Deborah A Nickerson, John D Potter, Robert E Schoen, Fredrick R Schumacher, Daniela Seminara, Martha L Slattery, Li Hsu, Andrew T Chan, Emily White, Sonja I Berndt, Ulrike Peters
Published 2016-01-01

Genome-wide search for gene-gene interactions in colorectal cancer.

by Shuo Jiao, Li Hsu, Sonja Berndt, Stéphane Bézieau, Hermann Brenner, Daniel Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Stephen Chanock, David V Conti, Keith R Curtis, David Duggan, Steven Gallinger, Stephen B Gruber, Tabitha A Harrison, Richard B Hayes, Brian E Henderson, Michael Hoffmeister, John L Hopper, Thomas J Hudson, Carolyn M Hutter, Rebecca D Jackson, Mark A Jenkins, Elizabeth D Kantor, Laurence N Kolonel, Sébastien Küry, Loic Le Marchand, Mathieu Lemire, Polly A Newcomb, John D Potter, Conghui Qu, Stephanie A Rosse, Robert E Schoen, Fred R Schumacher, Daniela Seminara, Martha L Slattery, Cornelia M Ulrich, Brent W Zanke, Ulrike Peters
Published 2012-01-01

Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer.

by Jian Gong, Carolyn M Hutter, Polly A Newcomb, Cornelia M Ulrich, Stephanie A Bien, Peter T Campbell, John A Baron, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Mengmeng Du, David Duggan, Jane C Figueiredo, Steven Gallinger, Edward L Giovannucci, Robert W Haile, Tabitha A Harrison, Richard B Hayes, Michael Hoffmeister, John L Hopper, Thomas J Hudson, Jihyoun Jeon, Mark A Jenkins, Jonathan Kocarnik, Sébastien Küry, Loic Le Marchand, Yi Lin, Noralane M Lindor, Reiko Nishihara, Shuji Ogino, John D Potter, Anja Rudolph, Robert E Schoen, Petra Schrotz-King, Daniela Seminara, Martha L Slattery, Stephen N Thibodeau, Mark Thornquist, Reka Toth, Robert Wallace, Emily White, Shuo Jiao, Mathieu Lemire, Li Hsu, Ulrike Peters, CCFR and GECCO
Published 2016-10-01

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.

by Ian P M Tomlinson, Luis G Carvajal-Carmona, Sara E Dobbins, Albert Tenesa, Angela M Jones, Kimberley Howarth, Claire Palles, Peter Broderick, Emma E M Jaeger, Susan Farrington, Annabelle Lewis, James G D Prendergast, Alan M Pittman, Evropi Theodoratou, Bianca Olver, Marion Walker, Steven Penegar, Ella Barclay, Nicola Whiffin, Lynn Martin, Stephane Ballereau, Amy Lloyd, Maggie Gorman, Steven Lubbe, COGENT Consortium, CORGI Collaborators, EPICOLON Consortium, Bryan Howie, Jonathan Marchini, Clara Ruiz-Ponte, Ceres Fernandez-Rozadilla, Antoni Castells, Angel Carracedo, Sergi Castellvi-Bel, David Duggan, David Conti, Jean-Baptiste Cazier, Harry Campbell, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G Martin, Grant W Montgomery, Joanne Young, Paul N Baird, Steven Gallinger, Polly Newcomb, John Hopper, Mark A Jenkins, Lauri A Aaltonen, David J Kerr, Jeremy Cheadle, Paul Pharoah, Graham Casey, Richard S Houlston, Malcolm G Dunlop
Published 2011-06-01

Genome-wide diet-gene interaction analyses for risk of colorectal cancer.

by Jane C Figueiredo, Li Hsu, Carolyn M Hutter, Yi Lin, Peter T Campbell, John A Baron, Sonja I Berndt, Shuo Jiao, Graham Casey, Barbara Fortini, Andrew T Chan, Michelle Cotterchio, Mathieu Lemire, Steven Gallinger, Tabitha A Harrison, Loic Le Marchand, Polly A Newcomb, Martha L Slattery, Bette J Caan, Christopher S Carlson, Brent W Zanke, Stephanie A Rosse, Hermann Brenner, Edward L Giovannucci, Kana Wu, Jenny Chang-Claude, Stephen J Chanock, Keith R Curtis, David Duggan, Jian Gong, Robert W Haile, Richard B Hayes, Michael Hoffmeister, John L Hopper, Mark A Jenkins, Laurence N Kolonel, Conghui Qu, Anja Rudolph, Robert E Schoen, Fredrick R Schumacher, Daniela Seminara, Deanna L Stelling, Stephen N Thibodeau, Mark Thornquist, Greg S Warnick, Brian E Henderson, Cornelia M Ulrich, W James Gauderman, John D Potter, Emily White, Ulrike Peters, CCFR, GECCO
Published 2014-04-01

Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.

by Clara C Elbers, Yiran Guo, Vinicius Tragante, Erik P A van Iperen, Matthew B Lanktree, Berta Almoguera Castillo, Fang Chen, Lisa R Yanek, Mary K Wojczynski, Yun R Li, Bart Ferwerda, Christie M Ballantyne, Sarah G Buxbaum, Yii-Der Ida Chen, Wei-Min Chen, L Adrienne Cupples, Mary Cushman, Yanan Duan, David Duggan, Michele K Evans, Jyotika K Fernandes, Myriam Fornage, Melissa Garcia, W Timothy Garvey, Nicole Glazer, Felicia Gomez, Tamara B Harris, Indrani Halder, Virginia J Howard, Margaux F Keller, M Ilyas Kamboh, Charles Kooperberg, Stephen B Kritchevsky, Andrea LaCroix, Kiang Liu, Yongmei Liu, Kiran Musunuru, Anne B Newman, N Charlotte Onland-Moret, Jose Ordovas, Inga Peter, Wendy Post, Susan Redline, Steven E Reis, Richa Saxena, Pamela J Schreiner, Kelly A Volcik, Xingbin Wang, Salim Yusuf, Alan B Zonderland, Sonia S Anand, Diane M Becker, Bruce Psaty, Daniel J Rader, Alex P Reiner, Stephen S Rich, Jerome I Rotter, Michèle M Sale, Michael Y Tsai, Ingrid B Borecki, Robert A Hegele, Sekar Kathiresan, Michael A Nalls, Herman A Taylor, Hakon Hakonarson, Suthesh Sivapalaratnam, Folkert W Asselbergs, Fotios Drenos, James G Wilson, Brendan J Keating
Published 2012-01-01

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.

by Ying Wu, Lindsay L Waite, Anne U Jackson, Wayne H-H Sheu, Steven Buyske, Devin Absher, Donna K Arnett, Eric Boerwinkle, Lori L Bonnycastle, Cara L Carty, Iona Cheng, Barbara Cochran, Damien C Croteau-Chonka, Logan Dumitrescu, Charles B Eaton, Nora Franceschini, Xiuqing Guo, Brian E Henderson, Lucia A Hindorff, Eric Kim, Leena Kinnunen, Pirjo Komulainen, Wen-Jane Lee, Loic Le Marchand, Yi Lin, Jaana Lindström, Oddgeir Lingaas-Holmen, Sabrina L Mitchell, Narisu Narisu, Jennifer G Robinson, Fred Schumacher, Alena Stančáková, Jouko Sundvall, Yun-Ju Sung, Amy J Swift, Wen-Chang Wang, Lynne Wilkens, Tom Wilsgaard, Alicia M Young, Linda S Adair, Christie M Ballantyne, Petra Bůžková, Aravinda Chakravarti, Francis S Collins, David Duggan, Alan B Feranil, Low-Tone Ho, Yi-Jen Hung, Steven C Hunt, Kristian Hveem, Jyh-Ming J Juang, Antero Y Kesäniemi, Johanna Kuusisto, Markku Laakso, Timo A Lakka, I-Te Lee, Mark F Leppert, Tara C Matise, Leena Moilanen, Inger Njølstad, Ulrike Peters, Thomas Quertermous, Rainer Rauramaa, Jerome I Rotter, Jouko Saramies, Jaakko Tuomilehto, Matti Uusitupa, Tzung-Dau Wang, Michael Boehnke, Christopher A Haiman, Yii-Der I Chen, Charles Kooperberg, Themistocles L Assimes, Dana C Crawford, Chao A Hsiung, Kari E North, Karen L Mohlke
Published 2013-03-01

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

by Philip J. Law, Maria Timofeeva, Ceres Fernandez-Rozadilla, Peter Broderick, James Studd, Juan Fernandez-Tajes, Susan Farrington, Victoria Svinti, Claire Palles, Giulia Orlando, Amit Sud, Amy Holroyd, Steven Penegar, Evropi Theodoratou, Peter Vaughan-Shaw, Harry Campbell, Lina Zgaga, Caroline Hayward, Archie Campbell, Sarah Harris, Ian J. Deary, John Starr, Laura Gatcombe, Maria Pinna, Sarah Briggs, Lynn Martin, Emma Jaeger, Archana Sharma-Oates, James East, Simon Leedham, Roland Arnold, Elaine Johnstone, Haitao Wang, David Kerr, Rachel Kerr, Tim Maughan, Richard Kaplan, Nada Al-Tassan, Kimmo Palin, Ulrika A. Hänninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Johan G. Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, Laura Renkonen-Sinisalo, Anna Lepistö, Jan Böhm, Jukka-Pekka Mecklin, Daniel D. Buchanan, Aung-Ko Win, John Hopper, Mark E. Jenkins, Noralane M. Lindor, Polly A. Newcomb, Steven Gallinger, David Duggan, Graham Casey, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Douglas F. Easton, Paul D. P. Pharoah, Julian Peto, Federico Canzian, Anthony Swerdlow, Rosalind A. Eeles, Zsofia Kote-Jarai, Kenneth Muir, Nora Pashayan, The PRACTICAL consortium, Andrea Harkin, Karen Allan, John McQueen, James Paul, Timothy Iveson, Mark Saunders, Katja Butterbach, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Iva Kirac, Petar Matošević, Philipp Hofer, Stefanie Brezina, Andrea Gsur, Jeremy P. Cheadle, Lauri A. Aaltonen, Ian Tomlinson, Richard S. Houlston, Malcolm G. Dunlop
Published 2019-05-01