Improved Genetic Profiling of Anthropometric Traits Using a Big Data Approach.

by Oriol Canela-Xandri, Konrad Rawlik, John A Woolliams, Albert Tenesa
Published 2016-01-01

Model selection approach suggests causal association between 25-hydroxyvitamin D and colorectal cancer.

by Lina Zgaga, Felix Agakov, Evropi Theodoratou, Susan M Farrington, Albert Tenesa, Malcolm G Dunlop, Paul McKeigue, Harry Campbell
Published 2013-01-01

Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability

by Michael D. Morgan, Erola Pairo-Castineira, Konrad Rawlik, Oriol Canela-Xandri, Jonathan Rees, David Sims, Albert Tenesa, Ian J. Jackson
Published 2018-12-01

Alzheimer's Disease Genes Are Associated with Measures of Cognitive Ageing in the Lothian Birth Cohorts of 1921 and 1936

by Gillian Hamilton, Sarah E. Harris, Gail Davies, David C. Liewald, Albert Tenesa, John M. Starr, David Porteous, Ian J. Deary
Published 2011-01-01

Epigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of complex traits in cattle and human

by Shuli Liu, Ying Yu, Shengli Zhang, John B. Cole, Albert Tenesa, Ting Wang, Tara G. McDaneld, Li Ma, George E. Liu, Lingzhao Fang
Published 2020-07-01

Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis.

by Evropi Theodoratou, Tom Palmer, Lina Zgaga, Susan M Farrington, Paul McKeigue, Farhat V N Din, Albert Tenesa, George Davey-Smith, Malcolm G Dunlop, Harry Campbell
Published 2012-01-01

Complex variation in measures of general intelligence and cognitive change.

by Suzanne J Rowe, Amy Rowlatt, Gail Davies, Sarah E Harris, David J Porteous, David C Liewald, Geraldine McNeill, John M Starr, Ian J Deary, Albert Tenesa
Published 2013-01-01

Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations

by Lingzhao Fang, Shuli Liu, Mei Liu, Xiaolong Kang, Shudai Lin, Bingjie Li, Erin E. Connor, Ransom L. Baldwin, Albert Tenesa, Li Ma, George E. Liu, Cong-jun Li
Published 2019-08-01

The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study.

by Lina Zgaga, Evropi Theodoratou, Janet Kyle, Susan M Farrington, Felix Agakov, Albert Tenesa, Marion Walker, Geraldine McNeill, Alan F Wright, Igor Rudan, Malcolm G Dunlop, Harry Campbell
Published 2012-01-01

Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits.

by Andrew D Bretherick, Oriol Canela-Xandri, Peter K Joshi, David W Clark, Konrad Rawlik, Thibaud S Boutin, Yanni Zeng, Carmen Amador, Pau Navarro, Igor Rudan, Alan F Wright, Harry Campbell, Veronique Vitart, Caroline Hayward, James F Wilson, Albert Tenesa, Chris P Ponting, J Kenneth Baillie, Chris Haley
Published 2020-07-01

Genetic copy number variation and general cognitive ability.

by Andrew K MacLeod, Gail Davies, Antony Payton, Albert Tenesa, Sarah E Harris, David Liewald, Xiayi Ke, Michelle Luciano, Lorna M Lopez, Alan J Gow, Janie Corley, Paul Redmond, Geraldine McNeill, Andrew Pickles, William Ollier, Michael Horan, John M Starr, Neil Pendleton, Pippa A Thomson, David J Porteous, Ian J Deary
Published 2012-01-01

Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways.

by Charlie W Lees, William J Zacharias, Mark Tremelling, Colin L Noble, Elaine R Nimmo, Albert Tenesa, Jennine Cornelius, Leif Torkvist, John Kao, Susan Farrington, Hazel E Drummond, Gwo-Tzer Ho, Ian D R Arnott, Henry D Appelman, Lauri Diehl, Harry Campbell, Malcolm G Dunlop, Miles Parkes, Sarah E M Howie, Deborah L Gumucio, Jack Satsangi
Published 2008-12-01

Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

by Yanni Zeng, Carmen Amador, Charley Xia, Riccardo Marioni, Duncan Sproul, Rosie M. Walker, Stewart W. Morris, Andrew Bretherick, Oriol Canela-Xandri, Thibaud S. Boutin, David W. Clark, Archie Campbell, Konrad Rawlik, Caroline Hayward, Reka Nagy, Albert Tenesa, David J. Porteous, James F. Wilson, Ian J. Deary, Kathryn L. Evans, Andrew M. McIntosh, Pau Navarro, Chris S. Haley
Published 2019-03-01

Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

by Yanni Zeng, Carmen Amador, Charley Xia, Riccardo Marioni, Duncan Sproul, Rosie M. Walker, Stewart W. Morris, Andrew Bretherick, Oriol Canela-Xandri, Thibaud S. Boutin, David W. Clark, Archie Campbell, Konrad Rawlik, Caroline Hayward, Reka Nagy, Albert Tenesa, David J. Porteous, James F. Wilson, Ian J. Deary, Kathryn L. Evans, Andrew M. McIntosh, Pau Navarro, Chris S. Haley
Published 2019-05-01

Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee.

by Taye H Hamza, Honglei Chen, Erin M Hill-Burns, Shannon L Rhodes, Jennifer Montimurro, Denise M Kay, Albert Tenesa, Victoria I Kusel, Patricia Sheehan, Muthukrishnan Eaaswarkhanth, Dora Yearout, Ali Samii, John W Roberts, Pinky Agarwal, Yvette Bordelon, Yikyung Park, Liyong Wang, Jianjun Gao, Jeffery M Vance, Kenneth S Kendler, Silviu-Alin Bacanu, William K Scott, Beate Ritz, John Nutt, Stewart A Factor, Cyrus P Zabetian, Haydeh Payami
Published 2011-08-01

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

by J Kenneth Baillie, Andrew Bretherick, Christopher S Haley, Sara Clohisey, Alan Gray, Lucile P A Neyton, Jeffrey Barrett, Eli A Stahl, Albert Tenesa, Robin Andersson, J Ben Brown, Geoffrey J Faulkner, Marina Lizio, Ulf Schaefer, Carsten Daub, Masayoshi Itoh, Naoto Kondo, Timo Lassmann, Jun Kawai, IIBDGC Consortium, Damian Mole, Vladimir B Bajic, Peter Heutink, Michael Rehli, Hideya Kawaji, Albin Sandelin, Harukazu Suzuki, Jack Satsangi, Christine A Wells, Nir Hacohen, Thomas C Freeman, Yoshihide Hayashizaki, Piero Carninci, Alistair R R Forrest, David A Hume
Published 2018-03-01

Meta-analysis of mismatch repair polymorphisms within the cogent consortium for colorectal cancer susceptibility.

by Simone Picelli, Justo Lorenzo Bermejo, Jenny Chang-Claude, Michael Hoffmeister, Ceres Fernández-Rozadilla, Angel Carracedo, Antoni Castells, Sergi Castellví-Bel, Memebers of EPICOLON Consortium-Gastrointestinal Oncology Group of the Spanish Gastroenterological Association, Alessio Naccarati, Barbara Pardini, Ludmila Vodickova, Heiko Müller, Bente A Talseth-Palmer, Geoffrey Stibbard, Paolo Peterlongo, Carmela Nici, Silvia Veneroni, Li Li, Graham Casey, Albert Tenesa, Susan M Farrington, Ian Tomlinson, Victor Moreno, Tom van Wezel, Juul Wijnen, Malcolm Dunlop, Paolo Radice, Rodney J Scott, Pavel Vodicka, Clara Ruiz-Ponte, Hermann Brenner, Stephan Buch, Henry Völzke, Jochen Hampe, Clemens Schafmayer, Annika Lindblom
Published 2013-01-01

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.

by Ian P M Tomlinson, Luis G Carvajal-Carmona, Sara E Dobbins, Albert Tenesa, Angela M Jones, Kimberley Howarth, Claire Palles, Peter Broderick, Emma E M Jaeger, Susan Farrington, Annabelle Lewis, James G D Prendergast, Alan M Pittman, Evropi Theodoratou, Bianca Olver, Marion Walker, Steven Penegar, Ella Barclay, Nicola Whiffin, Lynn Martin, Stephane Ballereau, Amy Lloyd, Maggie Gorman, Steven Lubbe, COGENT Consortium, CORGI Collaborators, EPICOLON Consortium, Bryan Howie, Jonathan Marchini, Clara Ruiz-Ponte, Ceres Fernandez-Rozadilla, Antoni Castells, Angel Carracedo, Sergi Castellvi-Bel, David Duggan, David Conti, Jean-Baptiste Cazier, Harry Campbell, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G Martin, Grant W Montgomery, Joanne Young, Paul N Baird, Steven Gallinger, Polly Newcomb, John Hopper, Mark A Jenkins, Lauri A Aaltonen, David J Kerr, Jeremy Cheadle, Paul Pharoah, Graham Casey, Richard S Houlston, Malcolm G Dunlop
Published 2011-06-01

Evidence of inbreeding depression on human height.

by Ruth McQuillan, Niina Eklund, Nicola Pirastu, Maris Kuningas, Brian P McEvoy, Tõnu Esko, Tanguy Corre, Gail Davies, Marika Kaakinen, Leo-Pekka Lyytikäinen, Kati Kristiansson, Aki S Havulinna, Martin Gögele, Veronique Vitart, Albert Tenesa, Yurii Aulchenko, Caroline Hayward, Asa Johansson, Mladen Boban, Sheila Ulivi, Antonietta Robino, Vesna Boraska, Wilmar Igl, Sarah H Wild, Lina Zgaga, Najaf Amin, Evropi Theodoratou, Ozren Polašek, Giorgia Girotto, Lorna M Lopez, Cinzia Sala, Jari Lahti, Tiina Laatikainen, Inga Prokopenko, Mart Kals, Jorma Viikari, Jian Yang, Anneli Pouta, Karol Estrada, Albert Hofman, Nelson Freimer, Nicholas G Martin, Mika Kähönen, Lili Milani, Markku Heliövaara, Erkki Vartiainen, Katri Räikkönen, Corrado Masciullo, John M Starr, Andrew A Hicks, Laura Esposito, Ivana Kolčić, Susan M Farrington, Ben Oostra, Tatijana Zemunik, Harry Campbell, Mirna Kirin, Marina Pehlic, Flavio Faletra, David Porteous, Giorgio Pistis, Elisabeth Widén, Veikko Salomaa, Seppo Koskinen, Krista Fischer, Terho Lehtimäki, Andrew Heath, Mark I McCarthy, Fernando Rivadeneira, Grant W Montgomery, Henning Tiemeier, Anna-Liisa Hartikainen, Pamela A F Madden, Pio d'Adamo, Nicholas D Hastie, Ulf Gyllensten, Alan F Wright, Cornelia M van Duijn, Malcolm Dunlop, Igor Rudan, Paolo Gasparini, Peter P Pramstaller, Ian J Deary, Daniela Toniolo, Johan G Eriksson, Antti Jula, Olli T Raitakari, Andres Metspalu, Markus Perola, Marjo-Riitta Järvelin, André Uitterlinden, Peter M Visscher, James F Wilson, ROHgen Consortium
Published 2012-01-01

Modulation of genetic associations with serum urate levels by body-mass-index in humans.

by Jennifer E Huffman, Eva Albrecht, Alexander Teumer, Massimo Mangino, Karen Kapur, Toby Johnson, Zoltán Kutalik, Nicola Pirastu, Giorgio Pistis, Lorna M Lopez, Toomas Haller, Perttu Salo, Anuj Goel, Man Li, Toshiko Tanaka, Abbas Dehghan, Daniela Ruggiero, Giovanni Malerba, Albert V Smith, Ilja M Nolte, Laura Portas, Amanda Phipps-Green, Lora Boteva, Pau Navarro, Asa Johansson, Andrew A Hicks, Ozren Polasek, Tõnu Esko, John F Peden, Sarah E Harris, Federico Murgia, Sarah H Wild, Albert Tenesa, Adrienne Tin, Evelin Mihailov, Anne Grotevendt, Gauti K Gislason, Josef Coresh, Pio D'Adamo, Sheila Ulivi, Peter Vollenweider, Gerard Waeber, Susan Campbell, Ivana Kolcic, Krista Fisher, Margus Viigimaa, Jeffrey E Metter, Corrado Masciullo, Elisabetta Trabetti, Cristina Bombieri, Rossella Sorice, Angela Döring, Eva Reischl, Konstantin Strauch, Albert Hofman, Andre G Uitterlinden, Melanie Waldenberger, H-Erich Wichmann, Gail Davies, Alan J Gow, Nicola Dalbeth, Lisa Stamp, Johannes H Smit, Mirna Kirin, Ramaiah Nagaraja, Matthias Nauck, Claudia Schurmann, Kathrin Budde, Susan M Farrington, Evropi Theodoratou, Antti Jula, Veikko Salomaa, Cinzia Sala, Christian Hengstenberg, Michel Burnier, Reedik Mägi, Norman Klopp, Stefan Kloiber, Sabine Schipf, Samuli Ripatti, Stefano Cabras, Nicole Soranzo, Georg Homuth, Teresa Nutile, Patricia B Munroe, Nicholas Hastie, Harry Campbell, Igor Rudan, Claudia Cabrera, Chris Haley, Oscar H Franco, Tony R Merriman, Vilmundur Gudnason, Mario Pirastu, Brenda W Penninx, Harold Snieder, Andres Metspalu, Marina Ciullo, Peter P Pramstaller, Cornelia M van Duijn, Luigi Ferrucci, Giovanni Gambaro, Ian J Deary, Malcolm G Dunlop, James F Wilson, Paolo Gasparini, Ulf Gyllensten, Tim D Spector, Alan F Wright, Caroline Hayward, Hugh Watkins, Markus Perola, Murielle Bochud, W H Linda Kao, Mark Caulfield, Daniela Toniolo, Henry Völzke, Christian Gieger, Anna Köttgen, Veronique Vitart
Published 2015-01-01