Transcriptional Profiling of Stem Cells: Moving from Descriptive to Predictive Paradigms

by Christine A. Wells, Jarny Choi
Published 2019-08-01

Ten simple rules for navigating the computational aspect of an interdisciplinary PhD.

by Sabrina Islam, Christine A Wells
Published 2021-02-01

IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection

by Robert B. Ashman, Dipti Vijayan, Christine A. Wells
Published 2011-01-01

Human CD141+ Dendritic Cell and CD1c+ Dendritic Cell Undergo Concordant Early Genetic Programming after Activation in Humanized Mice In Vivo

by Yoshihito Minoda, Isaac Virshup, Ingrid Leal Rojas, Oscar Haigh, Yide Wong, John J. Miles, Christine A. Wells, Christine A. Wells, Kristen J. Radford
Published 2017-10-01

attract: A method for identifying core pathways that define cellular phenotypes.

by Jessica C Mar, Nicholas A Matigian, John Quackenbush, Christine A Wells
Published 2011-01-01

Toll-Like Receptors Drive Specific Patterns of Tolerance and Training on Restimulation of Macrophages

by Suzanne K. Butcher, Christine E. O’Carroll, Christine A. Wells, Ruaidhrí J. Carmody
Published 2018-05-01

The Impact of APP on Alzheimer-like Pathogenesis and Gene Expression in Down Syndrome iPSC-Derived Neurons

by Dmitry A. Ovchinnikov, Othmar Korn, Isaac Virshup, Christine A. Wells, Ernst J. Wolvetang
Published 2018-07-01

pathVar: a new method for pathway-based interpretation of gene expression variability

by Laurence de Torrente, Samuel Zimmerman, Deanne Taylor, Yu Hasegawa, Christine A. Wells, Jessica C. Mar
Published 2017-05-01

Transcriptional ontogeny of first trimester human fetal and placental mesenchymal stem cells: Gestational age versus niche

by Jennifer M. Ryan, Nicholas Matigian, Rebecca A. Pelekanos, Samuel Jesuadian, Christine A. Wells, Nicholas M. Fisk
Published 2014-12-01

Single-Cell Gene Expression Profiles Define Self-Renewing, Pluripotent, and Lineage Primed States of Human Pluripotent Stem Cells

by Shelley R. Hough, Matthew Thornton, Elizabeth Mason, Jessica C. Mar, Christine A. Wells, Martin F. Pera
Published 2014-06-01

Human iPSC-Derived Cerebellar Neurons from a Patient with Ataxia-Telangiectasia Reveal Disrupted Gene Regulatory Networks

by Sam P. Nayler, Joseph E. Powell, Joseph E. Powell, Darya P. Vanichkina, Othmar Korn, Christine A. Wells, Christine A. Wells, Refik Kanjhan, Jian Sun, Ryan J. Taft, Ryan J. Taft, Ryan J. Taft, Martin F. Lavin, Ernst J. Wolvetang
Published 2017-10-01

Gene Expression Variability as a Unifying Element of the Pluripotency Network

by Elizabeth A. Mason, Jessica C. Mar, Andrew L. Laslett, Martin F. Pera, John Quackenbush, Ernst Wolvetang, Christine A. Wells
Published 2014-08-01

A simple, scalable approach to building a cross-platform transcriptome atlas.

by Paul W Angel, Nadia Rajab, Yidi Deng, Chris M Pacheco, Tyrone Chen, Kim-Anh Lê Cao, Jarny Choi, Christine A Wells
Published 2020-09-01

Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern

by Nicholas Matigian, Gary Brooke, Faten Zaibak, Tony Rossetti, Katarina Kollar, Rebecca Pelekanos, Celena Heazlewood, Alan Mackay-Sim, Christine A. Wells, Kerry Atkinson
Published 2015-03-01

A cross-study transcriptional analysis of Parkinson's disease.

by Greg T Sutherland, Nicholas A Matigian, Alistair M Chalk, Matthew J Anderson, Peter A Silburn, Alan Mackay-Sim, Christine A Wells, George D Mellick
Published 2009-01-01

Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias

by Shahzya Chaudhury, Caitríona O’Connor, Ana Cañete, Joana Bittencourt-Silvestre, Evgenia Sarrou, Áine Prendergast, Jarny Choi, Pamela Johnston, Christine A. Wells, Brenda Gibson, Karen Keeshan
Published 2018-12-01

Dynamic Interplay of Innate and Adaptive Immunity During Sterile Retinal Inflammation: Insights From the Transcriptome

by Riccardo Natoli, Riccardo Natoli, Elizabeth Mason, Haihan Jiao, Aaron Chuah, Hardip Patel, Nilisha Fernando, Krisztina Valter, Krisztina Valter, Christine A. Wells, Jan Provis, Jan Provis, Matt Rutar
Published 2018-07-01

Variance of gene expression identifies altered network constraints in neurological disease.

by Jessica C Mar, Nicholas A Matigian, Alan Mackay-Sim, George D Mellick, Carolyn M Sue, Peter A Silburn, John J McGrath, John Quackenbush, Christine A Wells
Published 2011-08-01

A molecular classification of human mesenchymal stromal cells

by Florian Rohart, Elizabeth A. Mason, Nicholas Matigian, Rowland Mosbergen, Othmar Korn, Tyrone Chen, Suzanne Butcher, Jatin Patel, Kerry Atkinson, Kiarash Khosrotehrani, Nicholas M. Fisk, Kim-Anh Lê Cao, Christine A. Wells
Published 2016-03-01

NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease.

by Anthony L Cook, Alejandra M Vitale, Sugandha Ravishankar, Nicholas Matigian, Greg T Sutherland, Jiangou Shan, Ratneswary Sutharsan, Chris Perry, Peter A Silburn, George D Mellick, Murray L Whitelaw, Christine A Wells, Alan Mackay-Sim, Stephen A Wood
Published 2011-01-01