Activation of Cre recombinase alone can induce complete tumor regression.

by Yulin Li, Peter S Choi, Stephanie C Casey, Dean W Felsher
Published 2014-01-01

Functional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma.

by Louis A Saddic, Stacey Wirt, Hannes Vogel, Dean W Felsher, Julien Sage
Published 2011-05-01

Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis.

by Shelly Beer, Kimberly Komatsubara, David I Bellovin, Masashi Kurobe, Karl Sylvester, Dean W Felsher
Published 2008-06-01

Correction: Combined Analysis of Murine and Human Microarrays and ChIP Analysis Reveals Genes Associated with the Ability of MYC To Maintain Tumorigenesis

by Chi-Hwa Wu, Debashis Sahoo, Constadina Arvanitis, Nicole Bradon, David L. Dill, Dean W. Felsher
Published 2013-10-01

A mathematical model of tumor regression and recurrence after therapeutic oncogene inactivation

by Sharon S. Hori, Ling Tong, Srividya Swaminathan, Mariola Liebersbach, Jingjing Wang, Sanjiv S. Gambhir, Dean W. Felsher
Published 2021-01-01

Lipid nanoparticles that deliver IL-12 messenger RNA suppress tumorigenesis in MYC oncogene-driven hepatocellular carcinoma

by Ian Lai, Srividya Swaminathan, Virginie Baylot, Adriane Mosley, Renumathy Dhanasekaran, Meital Gabay, Dean W. Felsher
Published 2018-11-01

Combined analysis of murine and human microarrays and ChIP analysis reveals genes associated with the ability of MYC to maintain tumorigenesis.

by Chi-Hwa Wu, Debashis Sahoo, Constadina Arvanitis, Nicole Bradon, David L Dill, Dean W Felsher
Published 2008-06-01

Correction: Combined Analysis of Murine and Human Microarrays and ChIP Analysis Reveals Genes Associated with the Ability of MYC To Maintain Tumorigenesis.

by Chi-Hwa Wu, Debashis Sahoo, Constadina Arvanitis, Nicole Bradon, David L. Dill, Dean W. Felsher
Published 2013-10-01

Impact of hydrodynamic injection and phiC31 integrase on tumor latency in a mouse model of MYC-induced hepatocellular carcinoma.

by Lauren E Woodard, Annahita Keravala, W Edward Jung, Orly L Wapinski, Qiwei Yang, Dean W Felsher, Michele P Calos
Published 2010-06-01

SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas.

by Kyu Yun Jang, Sang Jae Noh, Nadja Lehwald, Guo-Zhong Tao, David I Bellovin, Ho Sung Park, Woo Sung Moon, Dean W Felsher, Karl G Sylvester
Published 2012-01-01

MYC ASO Impedes Tumorigenesis and Elicits Oncogene Addiction in Autochthonous Transgenic Mouse Models of HCC and RCC

by Renumathy Dhanasekaran, Jangho Park, Alekesey Yevtodiyenko, David I. Bellovin, Stacey J. Adam, Anand Rajan KD, Meital Gabay, Hanan Fernando, Julia Arzeno, Vinodhini Arjunan, Sergei Gryanzov, Dean W. Felsher
Published 2020-09-01

Combined Inactivation of MYC and K-Ras oncogenes reverses tumorigenesis in lung adenocarcinomas and lymphomas.

by Phuoc T Tran, Alice C Fan, Pavan K Bendapudi, Shan Koh, Kim Komatsubara, Joy Chen, George Horng, David I Bellovin, Sylvie Giuriato, Craig S Wang, Jeffrey A Whitsett, Dean W Felsher
Published 2008-05-01

MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies

by Srividya Swaminathan, Aida S. Hansen, Line D. Heftdal, Renumathy Dhanasekaran, Anja Deutzmann, Wadie D. M. Fernandez, Daniel F. Liefwalker, Crista Horton, Adriane Mosley, Mariola Liebersbach, Holden T. Maecker, Dean W. Felsher
Published 2020-06-01

Developmental context determines latency of MYC-induced tumorigenesis.

by Shelly Beer, Anders Zetterberg, Rebecca A Ihrie, Ryan A McTaggart, Qiwei Yang, Nicole Bradon, Constadina Arvanitis, Laura D Attardi, Sandy Feng, Boris Ruebner, Robert D Cardiff, Dean W Felsher
Published 2004-11-01

MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity

by Renumathy Dhanasekaran, Virginie Baylot, Minsoon Kim, Sibu Kuruvilla, David I Bellovin, Nia Adeniji, Anand Rajan KD, Ian Lai, Meital Gabay, Ling Tong, Maya Krishnan, Jangho Park, Theodore Hu, Mustafa A Barbhuiya, Andrew J Gentles, Kasthuri Kannan, Phuoc T Tran, Dean W Felsher
Published 2020-01-01

Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure.

by Hyoung-gon Lee, Qun Chen, Julie A Wolfram, Sandy L Richardson, Anna Liner, Sandra L Siedlak, Xiongwei Zhu, Nicholas P Ziats, Hisashi Fujioka, Dean W Felsher, Rudy J Castellani, Maria L Valencik, John A McDonald, Brian D Hoit, Edward J Lesnefsky, Mark A Smith
Published 2009-09-01

Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis.

by Phuoc T Tran, Emelyn H Shroff, Timothy F Burns, Saravanan Thiyagarajan, Sandhya T Das, Tahera Zabuawala, Joy Chen, Yoon-Jae Cho, Richard Luong, Pablo Tamayo, Tarek Salih, Khaled Aziz, Stacey J Adam, Silvestre Vicent, Carsten H Nielsen, Nadia Withofs, Alejandro Sweet-Cordero, Sanjiv S Gambhir, Charles M Rudin, Dean W Felsher
Published 2012-01-01

MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma

by Sean T. Bailey, Aleisha M. Smith, Jordan Kardos, Sara E. Wobker, Harper L. Wilson, Bhavani Krishnan, Ryoichi Saito, Hyo Jin Lee, Jing Zhang, Samuel C. Eaton, Lindsay A. Williams, Ujjawal Manocha, Dorien J. Peters, Xinchao Pan, Thomas J. Carroll, Dean W. Felsher, Vonn Walter, Qing Zhang, Joel S. Parker, Jen Jen Yeh, Richard A. Moffitt, Janet Y. Leung, William Y. Kim
Published 2017-06-01