The PDAC Extracellular Matrix: A Review of the ECM Protein Composition, Tumor Cell Interaction, and Therapeutic Strategies

by Vincent M. Perez, Joseph F. Kearney, Joseph F. Kearney, Jen Jen Yeh, Jen Jen Yeh, Jen Jen Yeh
Published 2021-10-01

De novo compartment deconvolution and weight estimation of tumor samples using DECODER

by Xianlu Laura Peng, Richard A. Moffitt, Robert J. Torphy, Keith E. Volmar, Jen Jen Yeh
Published 2019-10-01

Metformin Treatment Does Not Inhibit Growth of Pancreatic Cancer Patient-Derived Xenografts.

by Matthew B Lipner, Raoud Marayati, Yangmei Deng, Xianxi Wang, Laura Raftery, Bert H O'Neil, Jen Jen Yeh
Published 2016-01-01

Fusobacterium is associated with colorectal adenomas.

by Amber N McCoy, Félix Araújo-Pérez, Andrea Azcárate-Peril, Jen Jen Yeh, Robert S Sandler, Temitope O Keku
Published 2013-01-01

Differential gene expression between African American and European American colorectal cancer patients.

by Biljana Jovov, Felix Araujo-Perez, Carlie S Sigel, Jeran K Stratford, Amber N McCoy, Jen Jen Yeh, Temitope Keku
Published 2012-01-01

Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability.

by Jeran K Stratford, Feng Yan, Rebecca A Hill, Michael B Major, Lee M Graves, Channing J Der, Jen Jen Yeh
Published 2017-01-01

mTOR inhibition induces compensatory, therapeutically targetable MEK activation in renal cell carcinoma.

by Sean T Bailey, Bing Zhou, Jeffrey S Damrauer, Bhavani Krishnan, Harper L Wilson, Aleisha M Smith, Mingqing Li, Jen Jen Yeh, William Y Kim
Published 2014-01-01

Circulating tumor cells as a biomarker of response to treatment in patient-derived xenograft mouse models of pancreatic adenocarcinoma.

by Robert J Torphy, Christopher J Tignanelli, Joyce W Kamande, Richard A Moffitt, Silvia G Herrera Loeza, Steven A Soper, Jen Jen Yeh
Published 2014-01-01

Gene Targeting in Disease Networks

by Deborah Weighill, Marouen Ben Guebila, Kimberly Glass, Kimberly Glass, Kimberly Glass, John Platig, John Platig, Jen Jen Yeh, John Quackenbush, John Quackenbush
Published 2021-04-01

Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma.

by Nina V Chaika, Fang Yu, Vinee Purohit, Kamiya Mehla, Audrey J Lazenby, Dominick DiMaio, Judy M Anderson, Jen Jen Yeh, Keith R Johnson, Michael A Hollingsworth, Pankaj K Singh
Published 2012-01-01

Isoform-specific upregulation of palladin in human and murine pancreas tumors.

by Silvia M Goicoechea, Brian Bednarski, Christianna Stack, David W Cowan, Keith Volmar, Leigh Thorne, Edna Cukierman, Anil K Rustgi, Teresa Brentnall, Rosa F Hwang, Christopher A G McCulloch, Jen Jen Yeh, David J Bentrem, Steven N Hochwald, Sunil R Hingorani, Hong Jin Kim, Carol A Otey
Published 2010-04-01

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation

by Yoshihito Kano, Teklab Gebregiworgis, Christopher B. Marshall, Nikolina Radulovich, Betty P. K. Poon, Jonathan St-Germain, Jonathan D. Cook, Ivette Valencia-Sama, Benjamin M. M. Grant, Silvia Gabriela Herrera, Jinmin Miao, Brian Raught, Meredith S. Irwin, Jeffrey E. Lee, Jen Jen Yeh, Zhong-Yin Zhang, Ming-Sound Tsao, Mitsuhiko Ikura, Michael Ohh
Published 2019-01-01

A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma.

by Jeran K Stratford, David J Bentrem, Judy M Anderson, Cheng Fan, Keith A Volmar, J S Marron, Elizabeth D Routh, Laura S Caskey, Jonathan C Samuel, Channing J Der, Leigh B Thorne, Benjamin F Calvo, Hong Jin Kim, Mark S Talamonti, Christine A Iacobuzio-Donahue, Michael A Hollingsworth, Charles M Perou, Jen Jen Yeh
Published 2010-07-01

Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree

by Audrey M Hendley, Arjun A Rao, Laura Leonhardt, Sudipta Ashe, Jennifer A Smith, Simone Giacometti, Xianlu L Peng, Honglin Jiang, David I Berrios, Mathias Pawlak, Lucia Y Li, Jonghyun Lee, Eric A Collisson, Mark S Anderson, Gabriela K Fragiadakis, Jen Jen Yeh, Chun Jimmie Ye, Grace E Kim, Valerie M Weaver, Matthias Hebrok
Published 2021-05-01

MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma

by Sean T. Bailey, Aleisha M. Smith, Jordan Kardos, Sara E. Wobker, Harper L. Wilson, Bhavani Krishnan, Ryoichi Saito, Hyo Jin Lee, Jing Zhang, Samuel C. Eaton, Lindsay A. Williams, Ujjawal Manocha, Dorien J. Peters, Xinchao Pan, Thomas J. Carroll, Dean W. Felsher, Vonn Walter, Qing Zhang, Joel S. Parker, Jen Jen Yeh, Richard A. Moffitt, Janet Y. Leung, William Y. Kim
Published 2017-06-01

Discrete microfluidics for the isolation of circulating tumor cell subpopulations targeting fibroblast activation protein alpha and epithelial cell adhesion molecule

by Małgorzata A. Witek, Rachel D. Aufforth, Hong Wang, Joyce W. Kamande, Joshua M. Jackson, Swathi R. Pullagurla, Mateusz L. Hupert, Jerry Usary, Weiya Z. Wysham, Dawud Hilliard, Stephanie Montgomery, Victoria Bae-Jump, Lisa A. Carey, Paola A. Gehrig, Matthew I. Milowsky, Charles M. Perou, John T. Soper, Young E. Whang, Jen Jen Yeh, George Martin, Steven A. Soper
Published 2017-07-01

The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.

by Federico Innocenti, Kouros Owzar, Chen Jiang, Amy S Etheridge, Raluca Gordân, Alexander B Sibley, Flora Mulkey, Donna Niedzwiecki, Dylan Glubb, Nicole Neel, Mark S Talamonti, David J Bentrem, Eric Seiser, Jen Jen Yeh, Katherine Van Loon, Howard McLeod, Mark J Ratain, Hedy L Kindler, Alan P Venook, Yusuke Nakamura, Michiaki Kubo, Gloria M Petersen, William R Bamlet, Robert R McWilliams
Published 2018-01-01

N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration

by Isidore Rigoutsos, Sang Kil Lee, Su Youn Nam, Simone Anfossi, Barbara Pasculli, Martin Pichler, Yi Jing, Cristian Rodriguez-Aguayo, Aristeidis G. Telonis, Simona Rossi, Cristina Ivan, Tina Catela Ivkovic, Linda Fabris, Peter M. Clark, Hui Ling, Masayoshi Shimizu, Roxana S. Redis, Maitri Y. Shah, Xinna Zhang, Yoshinaga Okugawa, Eun Jung Jung, Aristotelis Tsirigos, Li Huang, Jana Ferdin, Roberta Gafà, Riccardo Spizzo, Milena S. Nicoloso, Anurag N. Paranjape, Maryam Shariati, Aida Tiron, Jen Jen Yeh, Raul Teruel-Montoya, Lianchun Xiao, Sonia A. Melo, David Menter, Zhi-Qin Jiang, Elsa R. Flores, Massimo Negrini, Ajay Goel, Menashe Bar-Eli, Sendurai A. Mani, Chang Gong Liu, Gabriel Lopez-Berestein, Ioana Berindan-Neagoe, Manel Esteller, Scott Kopetz, Giovanni Lanza, George A. Calin
Published 2017-05-01