External data required timely response by the Trial Steering-Data Monitoring Committee for the NALoxone InVEstigation (N-ALIVE) pilot trial

by Sheila M. Bird, John Strang, Deborah Ashby, John Podmore, J. Roy Robertson, Sarah Welch, Angela M. Meade, Mahesh K.B. Parmar
Published 2017-03-01

REal-time Assessment of Community Transmission (REACT) of SARS-CoV-2 virus: Study protocol [version 2; peer review: 2 approved]

by Steven Riley, Christina Atchison, Deborah Ashby, Christl A. Donnelly, Wendy Barclay, Graham S. Cooke, Helen Ward, Ara Darzi, Paul Elliott, REACT study group
Published 2021-04-01

Nutritional Evaluation and Optimisation in Neonates (NEON) trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition: a randomised double-blind...

by Sabita Uthaya, Xinxue Liu, Daphne Babalis, Caroline Dore, Jane Warwick, Jimmy Bell, Louise Thomas, Deborah Ashby, Giuliana Durighel, Ash Ederies, Monica Yanez-Lopez, Neena Modi
Published 2016-03-01

Rituximab versus cyclophosphamide for the treatment of connective tissue disease-associated interstitial lung disease (RECITAL): study protocol for a randomised controlled trial

by Peter Saunders, Vicky Tsipouri, Gregory J. Keir, Deborah Ashby, Marcus D. Flather, Helen Parfrey, Daphne Babalis, Elisabetta A. Renzoni, Christopher P. Denton, Athol U. Wells, Toby M. Maher
Published 2017-06-01

SARS-CoV-2 antibody prevalence in England following the first peak of the pandemic

by Helen Ward, Christina Atchison, Matthew Whitaker, Kylie E. C. Ainslie, Joshua Elliott, Lucy Okell, Rozlyn Redd, Deborah Ashby, Christl A. Donnelly, Wendy Barclay, Ara Darzi, Graham Cooke, Steven Riley, Paul Elliott
Published 2021-02-01

Prevalence of antibody positivity to SARS-CoV-2 following the first peak of infection in England: Serial cross-sectional studies of 365,000 adults

by Helen Ward, Graham S. Cooke, Christina Atchison, Matthew Whitaker, Joshua Elliott, Maya Moshe, Jonathan C Brown, Barnaby Flower, Anna Daunt, Kylie Ainslie, Deborah Ashby, Christl A. Donnelly, Steven Riley, Ara Darzi, Wendy Barclay, Paul Elliott
Published 2021-05-01

Developing routinely recorded clinical data from electronic patient records as a national resource to improve neonatal health care: the Medicines for Neonates research programme

by Neena Modi, Deborah Ashby, Cheryl Battersby, Peter Brocklehurst, Zoe Chivers, Kate Costeloe, Elizabeth S Draper, Victoria Foster, Jacquie Kemp, Azeem Majeed, Joanna Murray, Stavros Petrou, Katherine Rogers, Shalini Santhakumaran, Sonia Saxena, Yevgeniy Statnikov, Hilary Wong, Alys Young
Published 2019-09-01

A randomised, double-blind, placebo-controlled study to evaluate the efficacy of oral azithromycin as a supplement to standard care for adult patients with acute exacerbations of a...

by Sebastian L Johnston, Matyas Szigeti, Mary Cross, Christopher Brightling, Rekha Chaudhuri, Timothy Harrison, Adel Mansur, Laura Robison, Zahid Sattar, David Jackson, Patrick Mallia, Ernie Wong, Christopher Corrigan, Bernard Higgins, Philip Ind, Dave Singh, Neil Thomson, Deborah Ashby, Anoop Chauhan
Published 2016-10-01

Levosimendan to prevent acute organ dysfunction in sepsis: the LeoPARDS RCT

by Anthony C Gordon, Shalini Santhakumaran, Farah Al-Beidh, Robert ML Orme, Gavin D Perkins, Mervyn Singer, Daniel F McAuley, Alexina J Mason, Josie K Ward, Kieran P O’Dea, Timothy Felton, Mary Cross, Janis Best-Lane, Jonas Lexow, Ashley Campbell, Deborah Ashby
Published 2018-11-01

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

by Jonathan A. Cook, Steven A. Julious, William Sones, Lisa V. Hampson, Catherine Hewitt, Jesse A. Berlin, Deborah Ashby, Richard Emsley, Dean A. Fergusson, Stephen J. Walters, Edward C. F. Wilson, Graeme Maclennan, Nigel Stallard, Joanne C. Rothwell, Martin Bland, Louise Brown, Craig R. Ramsay, Andrew Cook, David Armstrong, Doug Altman, Luke D. Vale
Published 2018-11-01

Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop

by Jonathan A Cook, Steven A Julious, William Sones, Lisa V Hampson, Catherine Hewitt, Jesse A Berlin, Deborah Ashby, Richard Emsley, Dean A Fergusson, Stephen J Walters, Edward CF Wilson, Graeme MacLennan, Nigel Stallard, Joanne C Rothwell, Martin Bland, Louise Brown, Craig R Ramsay, Andrew Cook, David Armstrong, Douglas Altman, Luke D Vale
Published 2019-10-01

Realising the full potential of data-enabled trials in the UK: a call for action

by Catherine Hewitt, Ian Roberts, Michael King, Irwin Nazareth, Alan Watkins, Frank Sullivan, Derek Stewart, Nick Freemantle, Jane Daniels, Tobias Dreischulte, Brooke Jackson, Michael Donnelly, Martin Landray, Martin Gulliford, David A Harrison, Adam Streeter, Jennifer Logue, Paula Williamson, Marion Campbell, Martin C Gulliford, Jamie Soames, Dheeraj Rai, Stephanie MacNeill, Marion Bennie, Jo Rycroft-Malone, Matthew R Sydes, Andrew Farmer, Martyn Lewis, Elizabeth Williamson, Xavier Griffin, Colin McCowan, John Wilding, Jennifer Quint, Agnieszka Michael, Murali Shyamsundar, Tom Denwood, Deborah Ashby, Jacqui Nuttall, Kate Williams, Doreen Tembo, David Harrison, Andrew Morris, Fiona Lobban, Claire Snowdon, Martin Gibson, Rhoswyn Walker, Will Whiteley, Nick Mills, Juliet Tizzard, Emer Brady, Guillermo Lopez Campos, Catrin Tudur Smith, Yolanda Barbachano, Steph Garfield-Birkbeck, Will Navaie, Martin O'Kane, Jonathan Sheffield, Paula Walker, Rhoswyn R Walker, Janet Valentine, Susan Beatty, Helen Bodmer, Paul Brocklehurst, Steph Garfield‑Birkbeck, Doug Gould, Thomas Hiemstra, Anna Higgins, Julia Hippisley‑Cox, Sasha Korniak, Marion Mafham, Kathleen Meeley, Chris Newby, Martin O’Kane, Mike Robling, Jo Rycroft‑Malone, Matthew Sydes, Hwyel Williams
Published 2021-06-01

A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with...

by Eric WFW Alton, David K Armstrong, Deborah Ashby, Katie J Bayfield, Diana Bilton, Emily V Bloomfield, A Christopher Boyd, June Brand, Ruaridh Buchan, Roberto Calcedo, Paula Carvelli, Mario Chan, Seng H Cheng, David S Collie, Steve Cunningham, Heather E Davidson, Gwyneth Davies, Jane C Davies, Lee A Davies, Maria H Dewar, Ann Doherty, Jackie Donovan, Natalie S Dwyer, Hala I Elgmati, Rosanna F Featherstone, Jemyr Gavino, Sabrina Gea-Sorli, Duncan M Geddes, James SR Gibson, Deborah R Gill, Andrew P Greening, Uta Griesenbach, David M Hansell, Katharine Harman, Tracy E Higgins, Samantha L Hodges, Stephen C Hyde, Laura Hyndman, J Alastair Innes, Joseph Jacob, Nancy Jones, Brian F Keogh, Maria P Limberis, Paul Lloyd-Evans, Alan W Maclean, Michelle C Manvell, Dominique McCormick, Michael McGovern, Gerry McLachlan, Cuixiang Meng, M Angeles Montero, Hazel Milligan, Laura J Moyce, Gordon D Murray, Andrew G Nicholson, Tina Osadolor, Javier Parra-Leiton, David J Porteous, Ian A Pringle, Emma K Punch, Kamila M Pytel, Alexandra L Quittner, Gina Rivellini, Clare J Saunders, Ronald K Scheule, Sarah Sheard, Nicholas J Simmonds, Keith Smith, Stephen N Smith, Najwa Soussi, Samia Soussi, Emma J Spearing, Barbara J Stevenson, Stephanie G Sumner-Jones, Minna Turkkila, Rosa P Ureta, Michael D Waller, Marguerite Y Wasowicz, James M Wilson, Paul Wolstenholme-Hogg
Published 2016-07-01