The Renin-Angiotensin system and SARS-CoV-2 infection: A role for the ACE2 receptor?

by Peter Sever, Sebastian L Johnston
Published 2020-05-01

Echinacea reduces antibiotic usage in children through respiratory tract infection prevention: a randomized, blinded, controlled clinical trial

by Mercedes Ogal, Sebastian L. Johnston, Peter Klein, Roland Schoop
Published 2021-04-01

The role of viral infections in exacerbations of chronic obstructive pulmonary disease and asthma

by Richard Hewitt, Hugo Farne, Andrew Ritchie, Emma Luke, Sebastian L. Johnston, Patrick Mallia
Published 2016-04-01

Tbet Deficiency Causes T Helper Cell Dependent Airways Eosinophilia and Mucus Hypersecretion in Response to Rhinovirus Infection.

by Nicholas Glanville, Tamlyn J Peel, Armin Schröder, Julia Aniscenko, Ross P Walton, Susetta Finotto, Sebastian L Johnston
Published 2016-09-01

Infecções e inflamação das vias aéreas nas exacerbações graves da DPOC: Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations

by Alberto Papi, Cinzia Maria Bellettato, Fausto Braccioni, Micaela Romagnoli, Paolo Casolari, Gaetano Caramori, Leonardo M Fabbri, Sebastian L Johnston
Published 2007-01-01

Rhinovirus-induced VP1-specific Antibodies are Group-specific and Associated With Severity of Respiratory Symptoms

by Katarzyna Niespodziana, Clarissa R. Cabauatan, David J. Jackson, Daniela Gallerano, Belen Trujillo-Torralbo, Ajerico del Rosario, Patrick Mallia, Rudolf Valenta, Sebastian L. Johnston
Published 2015-01-01

TLR3, TLR4 and TLRs7-9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma.

by Annemarie Sykes, Michael R Edwards, Jonathan Macintyre, Ajerico Del Rosario, Vera Gielen, Jennifer Haas, Onn Min Kon, Mark McHale, Sebastian L Johnston
Published 2013-01-01

Comparative Metabolomic Sampling of Upper and Lower Airways by Four Different Methods to Identify Biochemicals That May Support Bacterial Growth

by Hugo Farne, Helen T. Groves, Simren K. Gill, Isobel Stokes, Scott McCulloch, Edward Karoly, Maria-Belen Trujillo-Torralbo, Sebastian L. Johnston, Patrick Mallia, John S. Tregoning
Published 2018-12-01

Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium

by Peter McErlean, Peter McErlean, Audrey Kelly, Audrey Kelly, Jaideep Dhariwal, Jaideep Dhariwal, Max Kirtland, Max Kirtland, Julie Watson, Julie Watson, Ismael Ranz, Ismael Ranz, Janet Smith, Alka Saxena, David J. Cousins, David J. Cousins, Antoon Van Oosterhout, Roberto Solari, Roberto Solari, Michael R. Edwards, Michael R. Edwards, Sebastian L. Johnston, Sebastian L. Johnston, Paul Lavender, Paul Lavender
Published 2020-12-01

Correction: The Role of IL-15 Deficiency in the Pathogenesis of Virus-Induced Asthma Exacerbations.

by Vasile Laza-Stanca, Simon D. Message, Michael R. Edwards, Hayley L. Parker, Mihnea T. Zdrenghea, Tatiana Kebadze, Onn M. Kon, Patrick Mallia, Luminita A. Stanciu, Sebastian L. Johnston
Published 2012-04-01

The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations.

by Vasile Laza-Stanca, Simon D Message, Michael R Edwards, Hayley L Parker, Mihnea T Zdrenghea, Tatiana Kebadze, Onn M Kon, Patrick Mallia, Luminita A Stanciu, Sebastian L Johnston
Published 2011-07-01

M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations

by Alexandra Nikonova, Musa Khaitov, David J. Jackson, Stephanie Traub, Maria-Belen Trujillo-Torralbo, Dmitriy A. Kudlay, Anton S. Dvornikov, Ajerico del-Rosario, Rudolf Valenta, Luminita A. Stanciu, Rahim Khaitov, Sebastian L. Johnston
Published 2020-04-01

Review: The Nose as a Route for Therapy. Part 2 Immunotherapy

by Yorissa Padayachee, Sabine Flicker, Sophia Linton, Sophia Linton, John Cafferkey, Onn Min Kon, Sebastian L. Johnston, Anne K. Ellis, Martin Desrosiers, Paul Turner, Rudolf Valenta, Glenis Kathleen Scadding, Glenis Kathleen Scadding
Published 2021-07-01

Inhibiting AKT phosphorylation employing non-cytotoxic anthraquinones ameliorates TH2 mediated allergic airways disease and rhinovirus exacerbation.

by Caio Cesar de Souza Alves, Adam Collison, Luke Hatchwell, Maximilian Plank, Matthew Morten, Paul S Foster, Sebastian L Johnston, Cristiane França da Costa, Mauro Vieira de Almeida, Henrique Couto Teixeira, Ana Paula Ferreira, Joerg Mattes
Published 2013-01-01

miR-122 promotes virus-induced lung disease by targeting SOCS1

by Adam M. Collison, Leon A. Sokulsky, Elizabeth Kepreotes, Ana Pereira de Siqueira, Matthew Morten, Michael R. Edwards, Ross P. Walton, Nathan W. Bartlett, Ming Yang, Thi Hiep Nguyen, Sebastian L. Johnston, Paul S. Foster, Joerg Mattes
Published 2021-04-01

Cross-serotype immunity induced by immunization with a conserved rhinovirus capsid protein.

by Nicholas Glanville, Gary R McLean, Bruno Guy, Valerie Lecouturier, Catherine Berry, Yves Girerd, Christophe Gregoire, Ross P Walton, Rebecca M Pearson, Tatiana Kebadze, Nicolas Burdin, Nathan W Bartlett, Jeffrey W Almond, Sebastian L Johnston
Published 2013-01-01

Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation

by Anet Laanesoo, Egon Urgard, Kapilraj Periyasamy, Martti Laan, Yury A. Bochkov, Alar Aab, Nathaniel Magilnick, Margus Pooga, James E. Gern, Sebastian L. Johnston, Jonathan M. Coquet, Mark P. Boldin, Jesper Wengel, Alan Altraja, Grazyna Bochenek, Bogdan Jakiela, Ana Rebane
Published 2021-06-01

A randomised, double-blind, placebo-controlled study to evaluate the efficacy of oral azithromycin as a supplement to standard care for adult patients with acute exacerbations of a...

by Sebastian L Johnston, Matyas Szigeti, Mary Cross, Christopher Brightling, Rekha Chaudhuri, Timothy Harrison, Adel Mansur, Laura Robison, Zahid Sattar, David Jackson, Patrick Mallia, Ernie Wong, Christopher Corrigan, Bernard Higgins, Philip Ind, Dave Singh, Neil Thomson, Deborah Ashby, Anoop Chauhan
Published 2016-10-01

The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD.

by Kirsty E Russell, Kian Fan Chung, Colin J Clarke, Andrew L Durham, Patrick Mallia, Joseph Footitt, Sebastian L Johnston, Peter J Barnes, Simon R Hall, Karen D Simpson, Malcolm R Starkey, Philip M Hansbro, Ian M Adcock, Coen H Wiegman
Published 2016-01-01

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium.

by Louise Slater, Nathan W Bartlett, Jennifer J Haas, Jie Zhu, Simon D Message, Ross P Walton, Annemarie Sykes, Samer Dahdaleh, Deborah L Clarke, Maria G Belvisi, Onn M Kon, Takashi Fujita, Peter K Jeffery, Sebastian L Johnston, Michael R Edwards
Published 2010-11-01