Airway Epithelial Cells Generate Pro-inflammatory Tenascin-C and Small Extracellular Vesicles in Response to TLR3 Stimuli and Rhinovirus Infection

by Jake T. Mills, Jake T. Mills, Anja Schwenzer, Elizabeth K. Marsh, Michael R. Edwards, Ian Sabroe, Kim S. Midwood, Lisa C. Parker
Published 2019-08-01

TLR3, TLR4 and TLRs7-9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma.

by Annemarie Sykes, Michael R Edwards, Jonathan Macintyre, Ajerico Del Rosario, Vera Gielen, Jennifer Haas, Onn Min Kon, Mark McHale, Sebastian L Johnston
Published 2013-01-01

Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium

by Peter McErlean, Peter McErlean, Audrey Kelly, Audrey Kelly, Jaideep Dhariwal, Jaideep Dhariwal, Max Kirtland, Max Kirtland, Julie Watson, Julie Watson, Ismael Ranz, Ismael Ranz, Janet Smith, Alka Saxena, David J. Cousins, David J. Cousins, Antoon Van Oosterhout, Roberto Solari, Roberto Solari, Michael R. Edwards, Michael R. Edwards, Sebastian L. Johnston, Sebastian L. Johnston, Paul Lavender, Paul Lavender
Published 2020-12-01

Correction: The Role of IL-15 Deficiency in the Pathogenesis of Virus-Induced Asthma Exacerbations.

by Vasile Laza-Stanca, Simon D. Message, Michael R. Edwards, Hayley L. Parker, Mihnea T. Zdrenghea, Tatiana Kebadze, Onn M. Kon, Patrick Mallia, Luminita A. Stanciu, Sebastian L. Johnston
Published 2012-04-01

The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations.

by Vasile Laza-Stanca, Simon D Message, Michael R Edwards, Hayley L Parker, Mihnea T Zdrenghea, Tatiana Kebadze, Onn M Kon, Patrick Mallia, Luminita A Stanciu, Sebastian L Johnston
Published 2011-07-01

miR-122 promotes virus-induced lung disease by targeting SOCS1

by Adam M. Collison, Leon A. Sokulsky, Elizabeth Kepreotes, Ana Pereira de Siqueira, Matthew Morten, Michael R. Edwards, Ross P. Walton, Nathan W. Bartlett, Ming Yang, Thi Hiep Nguyen, Sebastian L. Johnston, Paul S. Foster, Joerg Mattes
Published 2021-04-01

Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways.

by Ann-Kathrin Reuschl, Michael R Edwards, Robert Parker, David W Connell, Long Hoang, Alice Halliday, Hannah Jarvis, Nazneen Siddiqui, Corrina Wright, Samuel Bremang, Sandra M Newton, Peter Beverley, Robin J Shattock, Onn Min Kon, Ajit Lalvani
Published 2017-09-01

Gut Microbiota and Bacterial DNA Suppress Autoimmunity by Stimulating Regulatory B Cells in a Murine Model of Lupus

by Qinghui Mu, Michael R. Edwards, Brianna K. Swartwout, Xavier Cabana Puig, Jiangdi Mao, Jing Zhu, Joe Grieco, Thomas E. Cecere, Meeta Prakash, Christopher M. Reilly, Christopher Puglisi, Prathyusha Bachali, Amrie C. Grammer, Peter E. Lipsky, Xin M. Luo
Published 2020-11-01

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium.

by Louise Slater, Nathan W Bartlett, Jennifer J Haas, Jie Zhu, Simon D Message, Ross P Walton, Annemarie Sykes, Samer Dahdaleh, Deborah L Clarke, Maria G Belvisi, Onn M Kon, Takashi Fujita, Peter K Jeffery, Sebastian L Johnston, Michael R Edwards
Published 2010-11-01

Correction: Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium.

by Louise Slater, Nathan W. Bartlett, Jennifer J. Haas, Jie Zhu, Simon D. Message, Ross P. Walton, Annemarie Sykes, Samer Dahdaleh, Deborah L. Clarke, Maria G. Belvisi, Onn M. Kon, Takashi Fujita, Peter K. Jeffery, Sebastian L. Johnston, Michael R. Edwards
Published 2012-04-01

Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors.

by Daniel M Reed, Gabor Foldes, Timothy Gatheral, Koralia E Paschalaki, Zsuzsanna Lendvai, Zsolt Bagyura, Tamas Nemeth, Judit Skopal, Bela Merkely, Aurica G Telcian, Leila Gogsadze, Michael R Edwards, Peter J Gough, John Bertin, Sebastian L Johnston, Sian E Harding, Jane A Mitchell
Published 2014-01-01

Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma.

by Nadine Upton, David J Jackson, Alexandra A Nikonova, Suzie Hingley-Wilson, Musa Khaitov, Ajerico Del Rosario, Stephanie Traub, Maria-Belen Trujillo-Torralbo, Max Habibi, Sarah L Elkin, Onn M Kon, Michael R Edwards, Patrick Mallia, Joseph Footitt, Jonathan Macintyre, Luminita A Stanciu, Sebastian L Johnston, Annemarie Sykes
Published 2017-01-01

Control of lupus nephritis by changes of gut microbiota

by Qinghui Mu, Husen Zhang, Xiaofeng Liao, Kaisen Lin, Hualan Liu, Michael R. Edwards, S. Ansar Ahmed, Ruoxi Yuan, Liwu Li, Thomas E. Cecere, David B. Branson, Jay L. Kirby, Poorna Goswami, Caroline M. Leeth, Kaitlin A. Read, Kenneth J. Oestreich, Miranda D. Vieson, Christopher M. Reilly, Xin M. Luo
Published 2017-07-01

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

by Aran Singanayagam, Nicholas Glanville, Jason L. Girkin, Yee Man Ching, Andrea Marcellini, James D. Porter, Marie Toussaint, Ross P. Walton, Lydia J. Finney, Julia Aniscenko, Jie Zhu, Maria-Belen Trujillo-Torralbo, Maria Adelaide Calderazzo, Chris Grainge, Su-Ling Loo, Punnam Chander Veerati, Prabuddha S. Pathinayake, Kristy S. Nichol, Andrew T. Reid, Phillip L. James, Roberto Solari, Peter A. B. Wark, Darryl A. Knight, Miriam F. Moffatt, William O. Cookson, Michael R. Edwards, Patrick Mallia, Nathan W. Bartlett, Sebastian L. Johnston
Published 2018-06-01