DNA Double Strand Break Response and Limited Repair Capacity in Mouse Elongated Spermatids

by Emad A. Ahmed, Harry Scherthan, Dirk G. de Rooij
Published 2015-12-01

Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice

by Mina L Kojima, Dirk G de Rooij, David C Page
Published 2019-02-01

Mouse TRIP13/PCH2 is required for recombination and normal higher-order chromosome structure during meiosis.

by Ignasi Roig, James A Dowdle, Attila Toth, Dirk G de Rooij, Maria Jasin, Scott Keeney
Published 2010-08-01

ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes.

by Marco Barchi, Ignasi Roig, Monica Di Giacomo, Dirk G de Rooij, Scott Keeney, Maria Jasin
Published 2008-05-01

Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Head Remodelling and Sperm Tail Development.

by Nadege Vernet, Shantha K Mahadevaiah, Fanny Decarpentrie, Guy Longepied, Dirk G de Rooij, Paul S Burgoyne, Michael J Mitchell
Published 2016-01-01

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline

by Alexis S Bailey, Pedro J Batista, Rebecca S Gold, Y Grace Chen, Dirk G de Rooij, Howard Y Chang, Margaret T Fuller
Published 2017-10-01

Dynamic and regulated TAF gene expression during mouse embryonic germ cell development.

by Megan A Gura, Maria M Mikedis, Kimberly A Seymour, Dirk G de Rooij, David C Page, Richard N Freiman
Published 2020-01-01

Meioc maintains an extended meiotic prophase I in mice.

by Y Q Shirleen Soh, Maria M Mikedis, Mina Kojima, Alexander K Godfrey, Dirk G de Rooij, David C Page
Published 2017-04-01

RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary.

by Anne-Amandine Chassot, Elodie P Gregoire, Rowena Lavery, Makoto M Taketo, Dirk G de Rooij, Ian R Adams, Marie-Christine Chaboissier
Published 2011-01-01

shRNA off-target effects in vivo: impaired endogenous siRNA expression and spermatogenic defects.

by Hye-Won Song, Anilkumar Bettegowda, Daniel Oliver, Wei Yan, Mimi H Phan, Dirk G de Rooij, Mark A Corbett, Miles F Wilkinson
Published 2015-01-01

DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors

by Maria M Mikedis, Yuting Fan, Peter K Nicholls, Tsutomu Endo, Emily K Jackson, Sarah A Cobb, Dirk G de Rooij, David C Page
Published 2020-07-01

A dominant, recombination-defective allele of Dmc1 causing male-specific sterility.

by Laura A Bannister, Roberto J Pezza, Janet R Donaldson, Dirk G de Rooij, Kerry J Schimenti, R Daniel Camerini-Otero, John C Schimenti
Published 2007-05-01

Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis.

by Mengcheng Luo, Jian Zhou, N Adrian Leu, Carla M Abreu, Jianle Wang, Montserrat C Anguera, Dirk G de Rooij, Maria Jasin, P Jeremy Wang
Published 2015-01-01

The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis

by Georgios Vlachogiannis, Chad E. Niederhuth, Salih Tuna, Athanasia Stathopoulou, Keijo Viiri, Dirk G. de Rooij, Richard G. Jenner, Robert J. Schmitz, Steen K.T. Ooi
Published 2015-02-01

The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis

by Georgios Vlachogiannis, Chad E. Niederhuth, Salih Tuna, Athanasia Stathopoulou, Keijo Viiri, Dirk G. de Rooij, Richard G. Jenner, Robert J. Schmitz, Steen K.T. Ooi
Published 2015-05-01

Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals.

by Rowena Lavery, Anne-Amandine Chassot, Eva Pauper, Elodie P Gregoire, Muriel Klopfenstein, Dirk G de Rooij, Manuel Mark, Andreas Schedl, Norbert B Ghyselinck, Marie-Christine Chaboissier
Published 2012-01-01

The Neonatal and Adult Human Testis Defined at the Single-Cell Level

by Abhishek Sohni, Kun Tan, Hye-Won Song, Dana Burow, Dirk G. de Rooij, Louise Laurent, Tung-Chin Hsieh, Raja Rabah, Saher Sue Hammoud, Elena Vicini, Miles F. Wilkinson
Published 2019-02-01

The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility.

by Laura Gómez-H, Natalia Felipe-Medina, Yazmine B Condezo, Rodrigo Garcia-Valiente, Isabel Ramos, José Angel Suja, José Luis Barbero, Ignasi Roig, Manuel Sánchez-Martín, Dirk G de Rooij, Elena Llano, Alberto M Pendas
Published 2019-08-01

C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility

by Laura Gómez-H, Natalia Felipe-Medina, Manuel Sánchez-Martín, Owen R. Davies, Isabel Ramos, Ignacio García-Tuñón, Dirk G. de Rooij, Ihsan Dereli, Attila Tóth, José Luis Barbero, Ricardo Benavente, Elena Llano, Alberto M. Pendas
Published 2016-10-01

UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells.

by Jee Young An, Euna Kim, Adriana Zakrzewska, Young Dong Yoo, Jun Min Jang, Dong Hoon Han, Min Jae Lee, Jai Wha Seo, Yong Jun Lee, Tae-You Kim, Dirk G de Rooij, Bo Yeon Kim, Yong Tae Kwon
Published 2012-01-01