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Durai Sundar

Durai Sundar is an Indian computational biologist, bioinformatician and the current Head of the Department of Biochemical Engineering and Biotechnology at the Indian Institute of Technology, Delhi. He is known for his studies in the fields of genome editing tool designing, biological studies of natural drugs and metabolic engineering as well as for his participation in the Indo-Japanese collaborative research initiatives on anti-cancer drug development and is a life member of the National Academy of Sciences, India.

The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2012. Provided by Wikipedia

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SurvCNN: A Discrete Time-to-Event Cancer Survival Estimation Framework Using Image Representations of Omics Data

by Yogesh Kalakoti, Shashank Yadav, Durai Sundar
Published 2021-06-01

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2

Biosurfactants: Potential Agents for Controlling Cellular Communication, Motility, and Antagonism

by Jyoti Sharma, Durai Sundar, Preeti Srivastava
Published 2021-10-01

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3

Deep learning assisted multi-omics integration for survival and drug-response prediction in breast cancer

by Vidhi Malik, Yogesh Kalakoti, Durai Sundar
Published 2021-03-01

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4

The bitter barricading of prostaglandin biosynthesis pathway: understanding the molecular mechanism of selective cyclooxygenase-2 inhibition by amarogentin, a secoiridoid glycoside...

by Shantanu Shukla, Khushboo Bafna, Durai Sundar, Sunil S Thorat
Published 2014-01-01

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5

Possible Link between Higher Transmissibility of Alpha, Kappa and Delta Variants of SARS-CoV-2 and Increased Structural Stability of Its Spike Protein and hACE2 Affinity

by Vipul Kumar, Jasdeep Singh, Seyed E. Hasnain, Durai Sundar
Published 2021-08-01

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6

Mixed Inhibition of cPEPCK by Genistein, Using an Extended Binding Site Located Adjacent to Its Catalytic Cleft.

by Shashank Prakash Katiyar, Arpit Jain, Jaspreet Kaur Dhanjal, Durai Sundar
Published 2015-01-01

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7

Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers

by Vidhi Malik, Vipul Kumar, Sunil C. Kaul, Renu Wadhwa, Durai Sundar
Published 2021-01-01

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8

Identification and Characterization of Mortaparib<sup>Plus</sup>—A Novel Triazole Derivative That Targets Mortalin-p53 Interaction and Inhibits Cancer-Cell Proliferation by Wild-Ty...

by Anissa Nofita Sari, Ahmed Elwakeel, Jaspreet Kaur Dhanjal, Vipul Kumar, Durai Sundar, Sunil C. Kaul, Renu Wadhwa
Published 2021-02-01

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9

Mortaparib, a novel dual inhibitor of mortalin and PARP1, is a potential drug candidate for ovarian and cervical cancers

by Jayarani F. Putri, Priyanshu Bhargava, Jaspreet Kaur Dhanjal, Tomoko Yaguchi, Durai Sundar, Sunil C. Kaul, Renu Wadhwa
Published 2019-12-01

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10

Computational Structure-Based De Novo Design of Hypothetical Inhibitors against the Anti- Inflammatory Target COX-2.

by Jaspreet Kaur Dhanjal, Anith Kumar Sreenidhi, Khushboo Bafna, Shashank Prakash Katiyar, Sukriti Goyal, Abhinav Grover, Durai Sundar
Published 2015-01-01

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11

The complete chloroplast genome of Dendrobium nobile, an endangered medicinal orchid from north-east India and its comparison with related Dendrobium species

by Ruchishree Konhar, Manish Debnath, Santosh Vishwakarma, Atanu Bhattacharjee, Durai Sundar, Pramod Tandon, Debasis Dash, Devendra Kumar Biswal
Published 2019-11-01

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12

Genetic Risk Prediction of COVID-19 Susceptibility and Severity in the Indian Population

by P. Prakrithi, P. Prakrithi, Priya Lakra, Durai Sundar, Manav Kapoor, Mitali Mukerji, Ishaan Gupta, The Indian Genome Variation Consortium
Published 2021-10-01

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13

$Mutant p53<sup>L194F</sup> Harboring Luminal-A Breast Cancer Cells Are Refractory to Apoptosis and Cell Cycle Arrest in Response to Mortaparib<sup>Plus</sup>, a Multimodal Small Molecule Inhibitor$

Mutant p53<sup>L194F</sup> Harboring Luminal-A Breast Cancer Cells Are Refractory to Apoptosis and Cell Cycle Arrest in Response to Mortaparib<sup>Plus</sup>, a Multimodal Small Mo...

by Ahmed Elwakeel, Anissa Nofita Sari, Jaspreet Kaur Dhanjal, Hazna Noor Meidinna, Durai Sundar, Sunil C. Kaul, Renu Wadhwa
Published 2021-06-01

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Article
14

Bioinformatics and Molecular Insights to Anti-Metastasis Activity of Triethylene Glycol Derivatives

by Vidhi Malik, Sukant Garg, Sajal Afzal, Jaspreet Kaur Dhanjal, Chae-Ok Yun, Sunil C. Kaul, Durai Sundar, Renu Wadhwa
Published 2020-07-01

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15

Genome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemia

by Lata Rani, Nitin Mathur, Ritu Gupta, Ajay Gogia, Gurvinder Kaur, Jaspreet Kaur Dhanjal, Durai Sundar, Lalit Kumar, Atul Sharma
Published 2017-05-01

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16

Ashwagandha derived withanone targets TPX2-Aurora A complex: computational and experimental evidence to its anticancer activity.

by Abhinav Grover, Rumani Singh, Ashutosh Shandilya, Didik Priyandoko, Vibhuti Agrawal, Virendra S Bisaria, Renu Wadhwa, Sunil C Kaul, Durai Sundar
Published 2012-01-01

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17

Marine Carotenoid Fucoxanthin Possesses Anti-Metastasis Activity: Molecular Evidence

by Sukant Garg, Sajal Afzal, Ahmed Elwakeel, Damini Sharma, Navaneethan Radhakrishnan, Jaspreet Kaur Dhanjal, Durai Sundar, Sunil C. Kaul, Renu Wadhwa
Published 2019-06-01

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18

Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells.

by Nupur Nigam, Abhinav Grover, Sukriti Goyal, Shashank P Katiyar, Priyanshu Bhargava, Pi-Chao Wang, Durai Sundar, Sunil C Kaul, Renu Wadhwa
Published 2015-01-01

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19

Molecular dynamics simulations and experimental studies reveal differential permeability of withaferin-A and withanone across the model cell membrane

by Renu Wadhwa, Neetu Singh Yadav, Shashank P. Katiyar, Tomoko Yaguchi, Chohee Lee, Hyomin Ahn, Chae-Ok Yun, Sunil C. Kaul, Durai Sundar
Published 2021-01-01

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20

Structure-Function Analyses of New SARS-CoV-2 Variants B.1.1.7, B.1.351 and B.1.1.28.1: Clinical, Diagnostic, Therapeutic and Public Health Implications

by Jasdeep Singh, Jasmine Samal, Vipul Kumar, Jyoti Sharma, Usha Agrawal, Nasreen Z. Ehtesham, Durai Sundar, Syed Asad Rahman, Subhash Hira, Seyed E. Hasnain
Published 2021-03-01

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