Assay Format as a Critical Success Factor for Identification of Novel Inhibitor Chemotypes of Tissue-Nonspecific Alkaline Phosphatase from High-Throughput Screening

by José Luis Millán, Eduard Sergienko, Thomas D.Y. Chung
Published 2010-04-01

Versatile assays for high throughput screening for activators or inhibitors of intracellular proteases and their cellular regulators.

by Hideki Hayashi, Michael Cuddy, Vincent Chih-Wen Shu, Kenneth W Yip, Charitha Madiraju, Paul Diaz, Toshifumi Matsuyama, Muneshige Kaibara, Kohtaro Taniyama, Stefan Vasile, Eduard Sergienko, John C Reed
Published 2009-10-01

TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response.

by Dmitri Rozanov, Anton Cheltsov, Eduard Sergienko, Stefan Vasile, Vladislav Golubkov, Alexander E Aleshin, Trevor Levin, Elie Traer, Byron Hann, Julia Freimuth, Nikita Alexeev, Max A Alekseyev, Sergey P Budko, Hans Peter Bächinger, Paul Spellman
Published 2015-01-01

Boosting NAD+ with a small molecule that activates NAMPT

by Stephen J. Gardell, Meghan Hopf, Asima Khan, Mauro Dispagna, E. Hampton Sessions, Rebecca Falter, Nidhi Kapoor, Jeanne Brooks, Jeffrey Culver, Chris Petucci, Chen-Ting Ma, Steven E. Cohen, Jun Tanaka, Emmanuel S. Burgos, Jennifer S. Hirschi, Steven R. Smith, Eduard Sergienko, Anthony B. Pinkerton
Published 2019-07-01