Assay Format as a Critical Success Factor for Identification of Novel Inhibitor Chemotypes of Tissue-Nonspecific Alkaline Phosphatase from High-Throughput Screening

by José Luis Millán, Eduard Sergienko, Thomas D.Y. Chung
Published 2010-04-01

How To Build a Bone: PHOSPHO1, Biomineralization, and Beyond

by Scott Dillon, Katherine A Staines, José Luis Millán, Colin Farquharson
Published 2019-07-01

Visualization of asfotase alfa-binding to sites of calcification in vivo

by Flavia Amadeu de Oliveira, Sonoko Narisawa, Massimo Bottini, José Luis Millán
Published 2020-10-01

Molecular players in biogenesis of mineralization-competent matrix vesicles

by Sandeep Chaudhary, Massimo Bottini, Sana Khalid, José Luis Millán, Dobrawa Napierala
Published 2020-10-01

Title not available

by Jesús Miguel Contreras Ramírez, Gerardo Martínez Albillos, José Luis Millán Rodríguez
Published 2019-01-01

The appearance and modulation of osteocyte marker expression during calcification of vascular smooth muscle cells.

by Dongxing Zhu, Neil Charles Wallace Mackenzie, José Luis Millán, Colin Farquharson, Vicky Elizabeth MacRae
Published 2011-01-01

Transgenic Overexpression of Tissue‐Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification

by Alexei Y. Savinov, Maryam Salehi, Manisha C. Yadav, Ilian Radichev, José Luis Millán, Olga V. Savinova
Published 2015-12-01

Functional significance of calcium binding to tissue-nonspecific alkaline phosphatase.

by Marc F Hoylaerts, Soetkin Van Kerckhoven, Tina Kiffer-Moreira, Campbell Sheen, Sonoko Narisawa, José Luis Millán
Published 2015-01-01

Chronic Kidney Disease-Induced Arterial Media Calcification in Rats Prevented by Tissue Non-Specific Alkaline Phosphatase Substrate Supplementation Rather Than Inhibition of the En...

by Britt Opdebeeck, Ellen Neven, José Luis Millán, Anthony B. Pinkerton, Patrick C. D’Haese, Anja Verhulst
Published 2021-07-01

Treatment with bone maturation and average lifespan of HPP model mice by AAV8-mediated neonatal gene therapy via single muscle injection

by Tae Matsumoto, Koichi Miyake, Noriko Miyake, Osamu Iijima, Kumi Adachi, Sonoko Narisawa, José Luis Millán, Hideo Orimo, Takashi Shimada
Published 2021-09-01

A robust transcriptional program in newts undergoing multiple events of lens regeneration throughout their lifespan

by Konstantinos Sousounis, Feng Qi, Manisha C Yadav, José Luis Millán, Fubito Toyama, Chikafumi Chiba, Yukiko Eguchi, Goro Eguchi, Panagiotis A Tsonis
Published 2015-11-01

Prenatal enzyme replacement therapy for Akp2−/− mice with lethal hypophosphatasia

by Akihiro Hasegawa, Aki Nakamura-Takahashi, Masataka Kasahara, Nana Saso, Sonoko Narisawa, José Luis Millán, Osamu Samura, Haruhiko Sago, Aikou Okamoto, Akihiro Umezawa
Published 2021-12-01

Phosphate Groups in the Lipid A Moiety Determine the Effects of LPS on Hepatic Stellate Cells: A Role for LPS-Dephosphorylating Activity in Liver Fibrosis

by Marlies Schippers, Eduard Post, Ilse Eichhorn, Jitske Langeland, Leonie Beljaars, Madhu S. Malo, Richard A. Hodin, José Luis Millán, Yury Popov, Detlef Schuppan, Klaas Poelstra
Published 2020-12-01

Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis.

by Matthew Pettengill, Juan D Matute, Megan Tresenriter, Julie Hibbert, David Burgner, Peter Richmond, José Luis Millán, Al Ozonoff, Tobias Strunk, Andrew Currie, Ofer Levy
Published 2017-01-01

Catalytic signature of a heat-stable, chimeric human alkaline phosphatase with therapeutic potential.

by Tina Kiffer-Moreira, Campbell R Sheen, Kellen Cristina da Silva Gasque, Mayte Bolean, Pietro Ciancaglini, Andrea van Elsas, Marc F Hoylaerts, José Luis Millán
Published 2014-01-01

Correction: Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis.

by Matthew Pettengill, Juan D Matute, Megan Tresenriter, Julie Hibbert, David Burgner, Peter Richmond, José Luis Millán, Al Ozonoff, Tobias Strunk, Andrew Currie, Ofer Levy
Published 2018-01-01

Tissue-nonspecific Alkaline Phosphatase Regulates Purinergic Transmission in the Central Nervous System During Development and Disease

by Álvaro Sebastián-Serrano, Laura de Diego-García, Carlos Martínez-Frailes, Jesús Ávila, Herbert Zimmermann, José Luis Millán, María Teresa Miras-Portugal, Miguel Díaz-Hernández
Published 2015-01-01

Central role of pyrophosphate in acellular cementum formation.

by Brian L Foster, Kanako J Nagatomo, Francisco H Nociti, Hanson Fong, Daisy Dunn, Anne B Tran, Wei Wang, Sonoko Narisawa, Jose Luis Millán, Martha J Somerman
Published 2012-01-01

Correction: Altered Bone Development and an Increase in FGF-23 Expression in Enpp1−/− Mice

by Neil Charles Wallace Mackenzie, Dongxing Zhu, Elspeth M. Milne, Rob van 't Hof, Aline Martin, Darryl Leigh Quarles, José Luis Millán, Colin Farquharson, Vicky Elisabeth MacRae
Published 2012-01-01

Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice.

by Neil Charles Wallace Mackenzie, Dongxing Zhu, Elspeth M Milne, Rob van 't Hof, Aline Martin, Leigh Darryl Quarles, José Luis Millán, Colin Farquharson, Vicky Elisabeth MacRae
Published 2012-01-01