Bile Acids Activated Receptors Regulate Innate Immunity

by Stefano Fiorucci, Michele Biagioli, Angela Zampella, Eleonora Distrutti
Published 2018-08-01

Probiotics VSL#3 protect against development of visceral pain in murine model of irritable bowel syndrome.

by Eleonora Distrutti, Sabrina Cipriani, Andrea Mencarelli, Barbara Renga, Stefano Fiorucci
Published 2013-01-01

VSL#3 resets insulin signaling and protects against NASH and atherosclerosis in a model of genetic dyslipidemia and intestinal inflammation.

by Andrea Mencarelli, Sabrina Cipriani, Barbara Renga, Angela Bruno, Claudio D'Amore, Eleonora Distrutti, Stefano Fiorucci
Published 2012-01-01

Bile Acids Activated Receptors in Inflammatory Bowel Disease

by Michele Biagioli, Silvia Marchianò, Adriana Carino, Cristina Di Giorgio, Luca Santucci, Eleonora Distrutti, Stefano Fiorucci
Published 2021-05-01

Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties

by Michele Biagioli, Daniela Capobianco, Adriana Carino, Silvia Marchianò, Chiara Fiorucci, Patrizia Ricci, Eleonora Distrutti, Stefano Fiorucci
Published 2019-02-01

The bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in mice.

by Andrea Mencarelli, Sabrina Cipriani, Barbara Renga, Daniela Francisci, Giuseppe Palladino, Eleonora Distrutti, Franco Baldelli, Stefano Fiorucci
Published 2010-01-01

Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation

by Michele Biagioli, Adriana Carino, Cristina Di Giorgio, Silvia Marchianò, Martina Bordoni, Rosalinda Roselli, Eleonora Distrutti, Stefano Fiorucci
Published 2020-06-01

Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP.

by Eleonora Distrutti, Julie-Ann O'Reilly, Claire McDonald, Sabrina Cipriani, Barbara Renga, Marina A Lynch, Stefano Fiorucci
Published 2014-01-01

Correction: The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis

by Sabrina Cipriani, Andrea Mencarelli, Maria Giovanna Chini, Eleonora Distrutti, Barbara Renga, Giuseppe Bifulco, Franco Baldelli, Annibale Donini, Stefano Fiorucci
Published 2013-01-01

The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis.

by Sabrina Cipriani, Andrea Mencarelli, Maria Giovanna Chini, Eleonora Distrutti, Barbara Renga, Giuseppe Bifulco, Franco Baldelli, Annibale Donini, Stefano Fiorucci
Published 2011-01-01

Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation.

by Andrea Mencarelli, Eleonora Distrutti, Barbara Renga, Claudio D'Amore, Sabrina Cipriani, Giuseppe Palladino, Annibale Donini, Patrizia Ricci, Stefano Fiorucci
Published 2011-01-01

Correction: The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis.

by Sabrina Cipriani, Andrea Mencarelli, Maria Giovanna Chini, Eleonora Distrutti, Barbara Renga, Giuseppe Bifulco, Franco Baldelli, Annibale Donini, Stefano Fiorucci
Published 2013-01-01

Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity

by Michele Biagioli, Luca Laghi, Adriana Carino, Sabrina Cipriani, Eleonora Distrutti, Silvia Marchianò, Carola Parolin, Paolo Scarpelli, Beatrice Vitali, Stefano Fiorucci
Published 2017-07-01

Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential

by Adriana Carino, Luigina Graziosi, Silvia Marchianò, Michele Biagioli, Elisabetta Marino, Valentina Sepe, Angela Zampella, Eleonora Distrutti, Annibale Donini, Stefano Fiorucci
Published 2021-05-01

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation.

by Barbara Renga, Andrea Mencarelli, Sabrina Cipriani, Claudio D'Amore, Adriana Carino, Angela Bruno, Daniela Francisci, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci
Published 2013-01-01

GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated HepatitisSummary

by Michele Biagioli, Adriana Carino, Chiara Fiorucci, Silvia Marchianò, Cristina Di Giorgio, Rosalinda Roselli, Margherita Magro, Eleonora Distrutti, Oxana Bereshchenko, Paolo Scarpelli, Angela Zampella, Stefano Fiorucci
Published 2019-01-01

Solomonsterol A, a Marine Pregnane-X-Receptor Agonist, Attenuates Inflammation and Immune Dysfunction in a Mouse Model of Arthritis

by Andrea Mencarelli, Claudio D'Amore, Barbara Renga, Sabrina Cipriani, Adriana Carino, Valentina Sepe, Elisa Perissutti, Maria Valeria D'Auria, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci
Published 2013-12-01

Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

by Adriana Carino, Federica Moraca, Federica Moraca, Bianca Fiorillo, Silvia Marchianò, Valentina Sepe, Michele Biagioli, Claudia Finamore, Silvia Bozza, Daniela Francisci, Eleonora Distrutti, Bruno Catalanotti, Angela Zampella, Stefano Fiorucci
Published 2020-10-01

Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

by Adriana Carino, Silvia Marchianò, Michele Biagioli, Chiara Fiorucci, Angela Zampella, Maria Chiara Monti, Elva Morretta, Martina Bordoni, Cristina Di Giorgio, Rosalinda Roselli, Patrizia Ricci, Eleonora Distrutti, Stefano Fiorucci
Published 2019-05-01

The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions

by Michele Biagioli, Adriana Carino, Chiara Fiorucci, Giannamaria Annunziato, Silvia Marchianò, Martina Bordoni, Rosalinda Roselli, Cristina Di Giorgio, Federica Castiglione, Patrizia Ricci, Agostino Bruno, Andrea Faccini, Eleonora Distrutti, Monia Baldoni, Gabriele Costantino, Stefano Fiorucci
Published 2019-08-01