FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats[S]

by Sabrina Cipriani, Andrea Mencarelli, Giuseppe Palladino, Stefano Fiorucci
Published 2010-04-01

Probiotics VSL#3 protect against development of visceral pain in murine model of irritable bowel syndrome.

by Eleonora Distrutti, Sabrina Cipriani, Andrea Mencarelli, Barbara Renga, Stefano Fiorucci
Published 2013-01-01

VSL#3 resets insulin signaling and protects against NASH and atherosclerosis in a model of genetic dyslipidemia and intestinal inflammation.

by Andrea Mencarelli, Sabrina Cipriani, Barbara Renga, Angela Bruno, Claudio D'Amore, Eleonora Distrutti, Stefano Fiorucci
Published 2012-01-01

The bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in mice.

by Andrea Mencarelli, Sabrina Cipriani, Barbara Renga, Daniela Francisci, Giuseppe Palladino, Eleonora Distrutti, Franco Baldelli, Stefano Fiorucci
Published 2010-01-01

The HIV matrix protein p17 subverts nuclear receptors expression and induces a STAT1-dependent proinflammatory phenotype in monocytes.

by Barbara Renga, Daniela Francisci, Claudio D'Amore, Elisabetta Schiaroli, Andrea Mencarelli, Sabrina Cipriani, Franco Baldelli, Stefano Fiorucci
Published 2012-01-01

Correction: The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis

by Sabrina Cipriani, Andrea Mencarelli, Maria Giovanna Chini, Eleonora Distrutti, Barbara Renga, Giuseppe Bifulco, Franco Baldelli, Annibale Donini, Stefano Fiorucci
Published 2013-01-01

The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis.

by Sabrina Cipriani, Andrea Mencarelli, Maria Giovanna Chini, Eleonora Distrutti, Barbara Renga, Giuseppe Bifulco, Franco Baldelli, Annibale Donini, Stefano Fiorucci
Published 2011-01-01

Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation.

by Andrea Mencarelli, Eleonora Distrutti, Barbara Renga, Claudio D'Amore, Sabrina Cipriani, Giuseppe Palladino, Annibale Donini, Patrizia Ricci, Stefano Fiorucci
Published 2011-01-01

Correction: The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis.

by Sabrina Cipriani, Andrea Mencarelli, Maria Giovanna Chini, Eleonora Distrutti, Barbara Renga, Giuseppe Bifulco, Franco Baldelli, Annibale Donini, Stefano Fiorucci
Published 2013-01-01

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation.

by Barbara Renga, Andrea Mencarelli, Sabrina Cipriani, Claudio D'Amore, Adriana Carino, Angela Bruno, Daniela Francisci, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci
Published 2013-01-01

Calcineurin B in CD4+ T Cells Prevents Autoimmune Colitis by Negatively Regulating the JAK/STAT Pathway

by Andrea Mencarelli, Maurizio Vacca, Maurizio Vacca, Hanif Javanmard Khameneh, Enzo Acerbi, Alicia Tay, Francesca Zolezzi, Michael Poidinger, Alessandra Mortellaro, Alessandra Mortellaro
Published 2018-02-01

Solomonsterol A, a Marine Pregnane-X-Receptor Agonist, Attenuates Inflammation and Immune Dysfunction in a Mouse Model of Arthritis

by Andrea Mencarelli, Claudio D'Amore, Barbara Renga, Sabrina Cipriani, Adriana Carino, Valentina Sepe, Elisa Perissutti, Maria Valeria D'Auria, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci
Published 2013-12-01

The Inflammasome Adaptor ASC Intrinsically Limits CD4+ T-Cell Proliferation to Help Maintain Intestinal Homeostasis

by Hanif Javanmard Khameneh, Keith Weng Kit Leong, Andrea Mencarelli, Maurizio Vacca, Bezaleel Mambwe, Bezaleel Mambwe, Kurt Neo, Alice Tay, Francesca Zolezzi, Bernett Lee, Alessandra Mortellaro, Alessandra Mortellaro
Published 2019-07-01

Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis.

by Barbara Renga, Andrea Mencarelli, Claudio D'Amore, Sabrina Cipriani, Maria Valeria D'Auria, Valentina Sepe, Maria Giovanna Chini, Maria Chiara Monti, Giuseppe Bifulco, Angela Zampella, Stefano Fiorucci
Published 2012-01-01

Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis

by Andrea Mencarelli, Hanif Javanmard Khameneh, Jan Fric, Maurizio Vacca, Sary El Daker, Baptiste Janela, Jing Ping Tang, Sabrina Nabti, Akhila Balachander, Tong Seng Lim, Florent Ginhoux, Paola Ricciardi-Castagnoli, Alessandra Mortellaro
Published 2018-03-01