Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis

by Catherine E. Diamond, Keith Weng Kit Leong, Maurizio Vacca, Jack Rivers-Auty, David Brough, Alessandra Mortellaro
Published 2017-07-01

Tyrosine Dephosphorylation of ASC Modulates the Activation of the NLRP3 and AIM2 Inflammasomes

by Bezaleel Mambwe, Bezaleel Mambwe, Kurt Neo, Hanif Javanmard Khameneh, Keith Weng Kit Leong, Mariasilvia Colantuoni, Mariasilvia Colantuoni, Maurizio Vacca, Richmond Muimo, Alessandra Mortellaro, Alessandra Mortellaro
Published 2019-07-01

The Inflammasome Adaptor ASC Intrinsically Limits CD4+ T-Cell Proliferation to Help Maintain Intestinal Homeostasis

by Hanif Javanmard Khameneh, Keith Weng Kit Leong, Andrea Mencarelli, Maurizio Vacca, Bezaleel Mambwe, Bezaleel Mambwe, Kurt Neo, Alice Tay, Francesca Zolezzi, Bernett Lee, Alessandra Mortellaro, Alessandra Mortellaro
Published 2019-07-01

An Immunoregulatory Role for Complement Receptors in Murine Models of Breast Cancer

by Fazrena Nadia Md Akhir, Mohd Hezmee Mohd Noor, Keith Weng Kit Leong, Jamileh A. Nabizadeh, Helga D. Manthey, Stefan E. Sonderegger, Jenny Nga Ting Fung, Crystal E. McGirr, Ian A. Shiels, Paul C. Mills, Trent M. Woodruff, Barbara E. Rolfe
Published 2021-01-01

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

by Maurizio Vacca, Maurizio Vacca, Julia Böhme, Lia Paola Zambetti, Hanif Javanmard Khameneh, Bhairav S. Paleja, Federica Laudisi, Adrian W. S. Ho, Kurt Neo, Keith Weng Kit Leong, Mardiana Marzuki, Bernett Lee, Michael Poidinger, Laura Santambrogio, Liana Tsenova, Francesca Zolezzi, Gennaro De Libero, Gennaro De Libero, Amit Singhal, Amit Singhal, Alessandra Mortellaro, Alessandra Mortellaro
Published 2017-11-01