Synthesis of enantiomerically pure (2S,3S)-5,5,5-trifluoroisoleucine and (2R,3S)-5,5,5-trifluoro-allo-isoleucine

by Holger Erdbrink, Elisabeth K. Nyakatura, Susanne Huhmann, Ulla I. M. Gerling, Dieter Lentz, Beate Koksch, Constantin Czekelius
Published 2013-10-01

Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins.

by Jose A Quiroz, Ryan J Malonis, Larissa B Thackray, Courtney A Cohen, Jesper Pallesen, Rohit K Jangra, Rebecca S Brown, Daniel Hofmann, Frederick W Holtsberg, Sergey Shulenin, Elisabeth K Nyakatura, Lorellin A Durnell, Vinayak Rayannavar, Johanna P Daily, Andrew B Ward, M Javad Aman, John M Dye, Kartik Chandran, Michael S Diamond, Margaret Kielian, Jonathan R Lai
Published 2019-11-01

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

by Katie A. Howell, Xiangguo Qiu, Jennifer M. Brannan, Christopher Bryan, Edgar Davidson, Frederick W. Holtsberg, Anna Z. Wec, Sergey Shulenin, Julia E. Biggins, Robin Douglas, Sven G. Enterlein, Hannah L. Turner, Jesper Pallesen, Charles D. Murin, Shihua He, Andrea Kroeker, Hong Vu, Andrew S. Herbert, Marnie L. Fusco, Elisabeth K. Nyakatura, Jonathan R. Lai, Zhen-Yong Keck, Steven K.H. Foung, Erica Ollmann Saphire, Larry Zeitlin, Andrew B. Ward, Kartik Chandran, Benjamin J. Doranz, Gary P. Kobinger, John M. Dye, M. Javad Aman
Published 2016-05-01