LGR5 is expressed by Ewing sarcoma and potentiates Wnt/β-catenin signaling

by Christopher A Scannell, Christopher A Scannell, Elisabeth A Pedersen, Jack T Mosher, Melanie Anne Krook, Lauren A Nicholls, Breelyn A Wilky, David M. Loeb, Elizabeth R Lawlor, Elizabeth R Lawlor
Published 2013-04-01

Micro-Environmental Stress Induces Src-Dependent Activation of Invadopodia and Cell Migration in Ewing Sarcoma

by Kelly M. Bailey, Merlin Airik, Melanie A. Krook, Elisabeth A. Pedersen, Elizabeth R. Lawlor
Published 2016-08-01

Microenvironmental Factors Drive Tenascin C and Src Cooperation to Promote Invadopodia Formation in Ewing Sarcoma

by Allegra G. Hawkins, Claire M. Julian, Sonja Konzen, Sydney Treichel, Elizabeth R. Lawlor, Kelly M. Bailey
Published 2019-10-01

DNA Methylation and Gene Expression Profiling of Ewing Sarcoma Primary Tumors Reveal Genes That Are Potential Targets of Epigenetic Inactivation

by Nikul Patel, Jennifer Black, Xi Chen, A. Mario Marcondes, William M. Grady, Elizabeth R. Lawlor, Scott C. Borinstein
Published 2012-01-01

GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.

by Jay Joo, Laura Christensen, Kegan Warner, Leith States, Hyung-Gyoo Kang, Kieuhoa Vo, Elizabeth R Lawlor, William A May
Published 2009-10-01

Differentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion.

by Bianca Karnuth, Nicolas Dedy, Tilmann Spieker, Elizabeth R Lawlor, Stefan Gattenlöhner, Andreas Ranft, Uta Dirksen, Heribert Jürgens, Andreas Bräuninger
Published 2014-01-01

Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer.

by Nicola R Brindle, Johanna A Joyce, Fanya Rostker, Elizabeth R Lawlor, Lamorna Swigart-Brown, Gerard Evan, Douglas Hanahan, Ksenya Shchors
Published 2015-01-01

Canonical Wnt/β-catenin signaling activation in soft-tissue sarcomas: A comparative study of synovial sarcoma and leiomyosarcoma

by Laurence M Briski, Dafydd G Thomas, Rajiv M Patel, Elizabeth R Lawlor, Rashmi Chugh, Jonathan B McHugh, David R Lucas
Published 2018-11-01

Modeling initiation of Ewing sarcoma in human neural crest cells.

by Cornelia von Levetzow, Xiaohua Jiang, Ynnez Gwye, Gregor von Levetzow, Long Hung, Aaron Cooper, Jessie Hao-Ru Hsu, Elizabeth R Lawlor
Published 2011-04-01

Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks

by Chris R. Evelyn, Erika M. Lisabeth, Susan M. Wade, Andrew J. Haak, Craig N. Johnson, Elizabeth R. Lawlor, Richard R. Neubig
Published 2016-05-01

Anatomic Origin of Osteochondrogenic Progenitors Impacts Sensitivity to EWS-FLI1-Induced Transformation

by Elise R. Pfaltzgraff, April Apfelbaum, Andrew P. Kassa, Jane Y. Song, Wei Jiang, Tahra K. Suhan, Deneen M. Wellik, Elizabeth R. Lawlor
Published 2019-03-01

BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization

by Felicia Gray, Hyo Je Cho, Shirish Shukla, Shihan He, Ashley Harris, Bohdan Boytsov, Łukasz Jaremko, Mariusz Jaremko, Borries Demeler, Elizabeth R. Lawlor, Jolanta Grembecka, Tomasz Cierpicki
Published 2016-11-01

Characterization and drug resistance patterns of Ewing's sarcoma family tumor cell lines.

by William A May, Rita S Grigoryan, Nino Keshelava, Daniel J Cabral, Laura L Christensen, Jasmine Jenabi, Lingyun Ji, Timothy J Triche, Elizabeth R Lawlor, C Patrick Reynolds
Published 2013-01-01

Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology Group.

by Michael J Monument, Kirsten M Johnson, Elizabeth McIlvaine, Lisa Abegglen, W Scott Watkins, Lynn B Jorde, Richard B Womer, Natalie Beeler, Laura Monovich, Elizabeth R Lawlor, Julia A Bridge, Joshua D Schiffman, Mark D Krailo, R Lor Randall, Stephen L Lessnick
Published 2014-01-01

A comprehensive promoter landscape identifies a novel promoter for CD133 in restricted tissues, cancers and stem cells

by Ramakrishna eSompallae, Oliver Marc Hofmann, Oliver Marc Hofmann, Christopher A Maher, Craig eGedye, Andreas eBehren, Morana eVitezic, Morana eVitezic, Carsten O Daub, Carsten O Daub, Sylvie eDevalle, Otavia L Caballero, Piero eCarninci, Yoshihide eHayashizaki, Elizabeth R Lawlor, Jonathan eCebon, Winston eHide, Winston eHide
Published 2013-10-01