Exploration of the Resistome and Druggable Genome Reveals New Mechanisms of Drug Resistance and Antimalarial Targets

by Annie Cowell, Elizabeth Winzeler
Published 2018-11-01

Synthesis and Bioactivity of Phthalimide Analogs as Potential Drugs to Treat Schistosomiasis, a Neglected Disease of Poverty

by Snigdha Singh, Nelly El-Sakkary, Danielle E. Skinner, Prem Prakash Sharma, Sabine Ottilie, Yevgeniya Antonova-Koch, Prashant Kumar, Elizabeth Winzeler, Poonam, Conor R. Caffrey, Brijesh Rathi
Published 2020-02-01

Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis

by Eva S Istvan, Sudipta Das, Suyash Bhatnagar, Josh R Beck, Edward Owen, Manuel Llinas, Suresh M Ganesan, Jacquin C Niles, Elizabeth Winzeler, Akhil B Vaidya, Daniel E Goldberg
Published 2019-03-01

A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine

by Satish K. Dhingra, Devasha Redhi, Jill M. Combrinck, Tomas Yeo, John Okombo, Philipp P. Henrich, Annie N. Cowell, Purva Gupta, Matthew L. Stegman, Jonathan M. Hoke, Roland A. Cooper, Elizabeth Winzeler, Sachel Mok, Timothy J. Egan, David A. Fidock, Thomas E. Wellems
Published 2017-05-01