Re-Envisioning Anti-Apicomplexan Parasite Drug Discovery Approaches

by Gabriel W. Rangel, Manuel Llinás, Manuel Llinás
Published 2021-06-01

Comment on “Emerging Functions of Transcription Factors in Malaria Parasite”

by Heather J. Painter, Manuel Llinás
Published 2012-01-01

Beyond the E-Value: Stratified Statistics for Protein Domain Prediction.

by Alejandro Ochoa, John D Storey, Manuel Llinás, Mona Singh
Published 2015-11-01

Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum

by Che J. Ngwa, Meike J. Kiesow, Olga Papst, Lindsey M. Orchard, Michael Filarsky, Alina N. Rosinski, Till S. Voss, Manuel Llinás, Manuel Llinás, Gabriele Pradel
Published 2017-07-01

Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite.

by Tracey L Campbell, Erandi K De Silva, Kellen L Olszewski, Olivier Elemento, Manuel Llinás
Published 2010-10-01

Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development

by Heather J. Painter, Neo Christopher Chung, Aswathy Sebastian, Istvan Albert, John D. Storey, Manuel Llinás
Published 2018-07-01

Identification and characterization of a liver stage-specific promoter region of the malaria parasite Plasmodium.

by Susanne Helm, Christine Lehmann, Andreas Nagel, Rebecca R Stanway, Sebastian Horstmann, Manuel Llinas, Volker T Heussler
Published 2010-01-01

The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during <i>Plasmodium falciparum</i> Gametocyte Development and Transmission

by Che Julius Ngwa, Meike Jutta Kiesow, Lindsey Marie Orchard, Afia Farrukh, Manuel Llinás, Gabriele Pradel
Published 2019-10-01

H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum

by Jessica Connacher, Gabrielle A. Josling, Lindsey M. Orchard, Janette Reader, Manuel Llinás, Lyn-Marié Birkholtz
Published 2021-04-01

The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum.

by Zbynek Bozdech, Manuel Llinás, Brian Lee Pulliam, Edith D Wong, Jingchun Zhu, Joseph L DeRisi
Published 2003-10-01

Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites

by Nanika Coetzee, Simone Sidoli, Riëtte van Biljon, Heather Painter, Manuel Llinás, Benjamin A. Garcia, Lyn-Marie Birkholtz
Published 2017-04-01

Dissecting the role of PfAP2-G in malaria gametocytogenesis

by Gabrielle A. Josling, Timothy J. Russell, Jarrett Venezia, Lindsey Orchard, Riëtte van Biljon, Heather J. Painter, Manuel Llinás
Published 2020-03-01

Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq

by Lia Chappell, Philipp Ross, Lindsey Orchard, Timothy J. Russell, Thomas D. Otto, Matthew Berriman, Julian C. Rayner, Manuel Llinás
Published 2020-06-01

Metabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolism.

by Ian A Lewis, Mark Wacker, Kellen L Olszewski, Simon A Cobbold, Katelynn S Baska, Asako Tan, Michael T Ferdig, Manuel Llinás
Published 2014-01-01

Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation

by Riëtte van Biljon, Roelof van Wyk, Heather J. Painter, Lindsey Orchard, Janette Reader, Jandeli Niemand, Manuel Llinás, Lyn-Marie Birkholtz
Published 2019-12-01

An erythrocyte vesicle protein exported by the malaria parasite promotes tubovesicular lipid import from the host cell surface.

by Pamela A Tamez, Souvik Bhattacharjee, Christiaan van Ooij, N Luisa Hiller, Manuel Llinás, Bharath Balu, John H Adams, Kasturi Haldar
Published 2008-08-01

Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum.

by Jessica K O'Hara, Lewis J Kerwin, Simon A Cobbold, Jonathan Tai, Thomas A Bedell, Paul J Reider, Manuel Llinás
Published 2014-01-01

Simultaneous genome-wide gene expression and transcript isoform profiling in the human malaria parasite.

by Lindsey B Turnbull, Geoffrey H Siwo, Katrina A Button-Simons, Asako Tan, Lisa A Checkley, Heather J Painter, Manuel Llinás, Michael T Ferdig
Published 2017-01-01

Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis

by Eva S Istvan, Sudipta Das, Suyash Bhatnagar, Josh R Beck, Edward Owen, Manuel Llinas, Suresh M Ganesan, Jacquin C Niles, Elizabeth Winzeler, Akhil B Vaidya, Daniel E Goldberg
Published 2019-03-01

The natural function of the malaria parasite’s chloroquine resistance transporter

by Sarah H. Shafik, Simon A. Cobbold, Kawthar Barkat, Sashika N. Richards, Nicole S. Lancaster, Manuel Llinás, Simon J. Hogg, Robert L. Summers, Malcolm J. McConville, Rowena E. Martin
Published 2020-08-01