Robust antibody and CD8+ T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria...

by Diego A. Espinosa, Dennis Christensen, Christian Muñoz, Sanjay Singh, Emily Locke, Peter Andersen, Fidel Zavala
Published 2017-04-01

Comparison of ELISA with electro-chemiluminescence technology for the qualitative and quantitative assessment of serological responses to vaccination

by Jessica S. Bolton, Sidhartha Chaudhury, Sheetij Dutta, Scott Gregory, Emily Locke, Tony Pierson, Elke S. Bergmann-Leitner
Published 2020-04-01

A no film slot blot for the detection of developing P. falciparum oocysts in mosquitoes.

by Bryan Grabias, Nitin Verma, Hong Zheng, Abhai K Tripathi, Godfree Mlambo, Merribeth J Morin, Emily Locke, Sanjai Kumar
Published 2017-01-01

Multiplex serological assay for establishing serological profiles of polymorphic, closely related peptide antigens

by Jessica Bolton, Sidhartha Chaudhury, Randall S. MacGill, Angela M. Early, C. Richter King, Emily Locke, Daniel E. Neafsey, Elke S. Bergmann-Leitner
Published 2021-01-01

Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages

by Yevel Flores-Garcia, Sonia M. Herrera, Hugo Jhun, Daniel W. Pérez-Ramos, C. Richter King, Emily Locke, Ramadevi Raghunandan, Fidel Zavala
Published 2019-12-01

Qualification of standard membrane-feeding assay with Plasmodium falciparum malaria and potential improvements for future assays.

by Kazutoyo Miura, Bingbing Deng, Gregory Tullo, Ababacar Diouf, Samuel E Moretz, Emily Locke, Merribeth Morin, Michael P Fay, Carole A Long
Published 2013-01-01

A slot blot immunoassay for quantitative detection of Plasmodium falciparum circumsporozoite protein in mosquito midgut oocyst.

by Sanjai Kumar, Hong Zheng, Bingbing Deng, Babita Mahajan, Bryan Grabias, Yukiko Kozakai, Merribeth J Morin, Emily Locke, Ashley Birkett, Kazutoyo Miura, Carole Long
Published 2014-01-01

Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

by Rama Raghunandan, Bryan T. Mayer, Yevel Flores-Garcia, Monica W. Gerber, Raphael Gottardo, Hugo Jhun, Sonia M. Herrera, Daniel W. Perez-Ramos, Emily Locke, C. Richter King, Fidel Zavala
Published 2020-03-01

Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum

by Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Gonzalo Gonzalez-Paez, Zhen Han, Katherine L. Williams, Wayne Volkmuth, Daniel Emerling, Emily Locke, C. Richter King, Fidel Zavala, Ian A. Wilson
Published 2021-02-01

Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.

by David Oyen, Jonathan L Torres, Phillip C Aoto, Yevel Flores-Garcia, Špela Binter, Tossapol Pholcharee, Sean Carroll, Sini Reponen, Rachael Wash, Qi Liang, Franck Lemiale, Emily Locke, Allan Bradley, C Richter King, Daniel Emerling, Paul Kellam, Fidel Zavala, Andrew B Ward, Ian A Wilson
Published 2020-03-01

Monoclonal antibodies block transmission of genetically diverse Plasmodium falciparum strains to mosquitoes

by Roos M. de Jong, Lisette Meerstein-Kessel, Dari F. Da, Sandrine Nsango, Joseph D. Challenger, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Elias Duarte, Noam Teyssier, Robert W. Sauerwein, Thomas S. Churcher, Roch K. Dabire, Isabelle Morlais, Emily Locke, Martijn A. Huynen, Teun Bousema, Matthijs M. Jore
Published 2021-08-01

Mosquito feeding assays to determine the infectiousness of naturally infected Plasmodium falciparum gametocyte carriers.

by Teun Bousema, Rhoel R Dinglasan, Rhoel R Dinglasan, Isabelle Morlais, Louis C Gouagna, Travis van Warmerdam, Parfait H Awono-Ambene, Sarah Bonnet, Mouctar Diallo, Mamadou Coulibaly, Timoléon Tchuinkam, Bert Mulder, Geoff Targett, Chris Drakeley, Colin Sutherland, Vincent Robert, Ogobara Doumbo, Yeya Touré, Patricia M Graves, Will Roeffen, Robert Sauerwein, Ashley Birkett, Emily Locke, Merribeth Morin, Yimin Wu, Thomas S Churcher
Published 2012-01-01