Using the antibody-antigen binding interface to train image-based deep neural networks for antibody-epitope classification.

by Daniel R Ripoll, Sidhartha Chaudhury, Anders Wallqvist
Published 2021-03-01

Molecular Simulations Reveal the Role of Antibody Fine Specificity and Viral Maturation State on Antibody-Dependent Enhancement of Infection in Dengue Virus

by Daniel R. Ripoll, Daniel R. Ripoll, Anders Wallqvist, Sidhartha Chaudhury
Published 2019-06-01

Optimized flow cytometric protocol for the detection of functional subsets of low frequency antigen-specific CD4+ and CD8+ T cells

by Marie Mura, Sidhartha Chaudhury, Fouzia Farooq, Elizabeth H. Duncan, Kevin Beck, Elke S. Bergmann-Leitner
Published 2020-01-01

Benchmarking and analysis of protein docking performance in Rosetta v3.2.

by Sidhartha Chaudhury, Monica Berrondo, Brian D Weitzner, Pravin Muthu, Hannah Bergman, Jeffrey J Gray
Published 2011-01-01

A delayed fractionated dose RTS,S AS01 vaccine regimen mediates protection via improved T follicular helper and B cell responses

by Suresh Pallikkuth, Sidhartha Chaudhury, Pinyi Lu, Li Pan, Erik Jongert, Ulrike Wille-Reece, Savita Pahwa
Published 2020-04-01

Comparison of ELISA with electro-chemiluminescence technology for the qualitative and quantitative assessment of serological responses to vaccination

by Jessica S. Bolton, Sidhartha Chaudhury, Sheetij Dutta, Scott Gregory, Emily Locke, Tony Pierson, Elke S. Bergmann-Leitner
Published 2020-04-01

Implementing sequence-based antigenic distance calculation into immunological shape space model

by Christopher S. Anderson, Mark Y. Sangster, Hongmei Yang, Thomas J. Mariani, Sidhartha Chaudhury, David J. Topham
Published 2020-06-01

Dengue virus antibody database: Systematically linking serotype-specificity with epitope mapping in dengue virus.

by Sidhartha Chaudhury, Gregory D Gromowski, Daniel R Ripoll, Ilja V Khavrutskii, Valmik Desai, Anders Wallqvist
Published 2017-02-01

Stochastic Model of the Adaptive Immune Response Predicts Disease Severity and Captures Enhanced Cross-Reactivity in Natural Dengue Infections

by Hung D. Nguyen, Hung D. Nguyen, Sidhartha Chaudhury, Adam T. Waickman, Heather Friberg, Jeffrey R. Currier, Anders Wallqvist
Published 2021-08-01

Quantitative predictions of binding free energy changes in drug-resistant influenza neuraminidase.

by Daniel R Ripoll, Ilja V Khavrutskii, Sidhartha Chaudhury, Jin Liu, Robert A Kuschner, Anders Wallqvist, Jaques Reifman
Published 2012-01-01

Computational and experimental validation of B and T-cell epitopes of the in vivo immune response to a novel malarial antigen.

by Elke S Bergmann-Leitner, Sidhartha Chaudhury, Nicholas J Steers, Mark Sabato, Vito Delvecchio, Anders S Wallqvist, Christian F Ockenhouse, Evelina Angov
Published 2013-01-01

Multiplex serological assay for establishing serological profiles of polymorphic, closely related peptide antigens

by Jessica Bolton, Sidhartha Chaudhury, Randall S. MacGill, Angela M. Early, C. Richter King, Emily Locke, Daniel E. Neafsey, Elke S. Bergmann-Leitner
Published 2021-01-01

Quantitative Analysis of Repertoire-Scale Immunoglobulin Properties in Vaccine-Induced B-Cell Responses

by Ilja V. Khavrutskii, Sidhartha Chaudhury, Sabrina M. Stronsky, Donald W. Lee, Jacqueline G. Benko, Anders Wallqvist, Sina Bavari, Christopher L. Cooper
Published 2017-08-01

Immunoprofiling Correlates of Protection Against SHIV Infection in Adjuvanted HIV-1 Pox-Protein Vaccinated Rhesus Macaques

by Pinyi Lu, Pinyi Lu, Dylan J. Guerin, Shu Lin, Sidhartha Chaudhury, Margaret E. Ackerman, Diane L. Bolton, Diane L. Bolton, Anders Wallqvist
Published 2021-05-01

Delayed fractional dose regimen of the RTS,S/AS01 malaria vaccine candidate enhances an IgG4 response that inhibits serum opsonophagocytosis

by Sidhartha Chaudhury, Jason A. Regules, Christian A. Darko, Sheetij Dutta, Anders Wallqvist, Norman C. Waters, Erik Jongert, Franck Lemiale, Elke S. Bergmann-Leitner
Published 2017-08-01

Serological profiles of pan-coronavirus-specific responses in COVID-19 patients using a multiplexed electro-chemiluminescence-based testing platform.

by Sidhartha Chaudhury, Jack Hutter, Jessica S Bolton, Shilpa Hakre, Evelyn Mose, Amy Wooten, William O'Connell, Joseph Hudak, Shelly J Krebs, Janice M Darden, Jason A Regules, Clinton K Murray, Kayvon Modjarrad, Paul Scott, Sheila Peel, Elke S Bergmann-Leitner
Published 2021-01-01

Rapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstruction.

by Sidhartha Chaudhury, Mohamed Diwan M Abdulhameed, Narender Singh, Gregory J Tawa, Patrik M D'haeseleer, Adam T Zemla, Ali Navid, Carol E Zhou, Matthew C Franklin, Jonah Cheung, Michael J Rudolph, James Love, John F Graf, David A Rozak, Jennifer L Dankmeyer, Kei Amemiya, Simon Daefler, Anders Wallqvist
Published 2013-01-01

IMRAS-A clinical trial of mosquito-bite immunization with live, radiation-attenuated P. falciparum sporozoites: Impact of immunization parameters on protective efficacy and generat...

by Bradley Hickey, Nimfa Teneza-Mora, Joanne Lumsden, Sharina Reyes, Martha Sedegah, Lindsey Garver, Michael R Hollingdale, Jo Glenna Banania, Harini Ganeshan, Megan Dowler, Anatalio Reyes, Cindy Tamminga, Alexandra Singer, Alicia Simmons, Maria Belmonte, Arnel Belmonte, Jun Huang, Sandra Inoue, Rachel Velasco, Steve Abot, Carlos S Vasquez, Ivelese Guzman, Mimi Wong, Patrick Twomey, Mariusz Wojnarski, James Moon, Yolanda Alcorta, Santina Maiolatesi, Michele Spring, Silas Davidson, Sidhartha Chaudhury, Eileen Villasante, Thomas L Richie, Judith E Epstein
Published 2020-01-01

Comprehensive Data Integration Approach to Assess Immune Responses and Correlates of RTS,S/AS01-Mediated Protection From Malaria Infection in Controlled Human Malaria Infection Tri...

by William Chad Young, Lindsay N. Carpp, Sidhartha Chaudhury, Jason A. Regules, Elke S. Bergmann-Leitner, Christian Ockenhouse, Ulrike Wille-Reece, Allan C. deCamp, Ellis Hughes, Celia Mahoney, Suresh Pallikkuth, Savita Pahwa, S. Moses Dennison, S. Moses Dennison, S. Moses Dennison, Sarah V. Mudrak, Sarah V. Mudrak, Sarah V. Mudrak, S. Munir Alam, S. Munir Alam, S. Munir Alam, Kelly E. Seaton, Kelly E. Seaton, Kelly E. Seaton, Rachel L. Spreng, Rachel L. Spreng, Rachel L. Spreng, Jon Fallon, Ashlin Michell, Fernando Ulloa-Montoya, Margherita Coccia, Erik Jongert, Galit Alter, Georgia D. Tomaras, Georgia D. Tomaras, Georgia D. Tomaras, Raphael Gottardo
Published 2021-06-01