Deep Learning Enables Fast and Accurate Imputation of Gene Expression

by Ramon Viñas, Tiago Azevedo, Eric R. Gamazon, Eric R. Gamazon, Eric R. Gamazon, Pietro Liò
Published 2021-04-01

The regulatory genome constrains protein sequence evolution: implications for the search for disease-associated genes

by Patrick Evans, Nancy J. Cox, Eric R. Gamazon
Published 2020-07-01

A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.

by Eric R Gamazon, Dan L Nicolae, Nancy J Cox
Published 2011-02-01

Multilayer modelling of the human transcriptome and biological mechanisms of complex diseases and traits

by Tiago Azevedo, Giovanna Maria Dimitri, Pietro Lió, Eric R. Gamazon
Published 2021-05-01

Comprehensive survey of SNPs in the Affymetrix exon array using the 1000 Genomes dataset.

by Eric R Gamazon, Wei Zhang, M Eileen Dolan, Nancy J Cox
Published 2010-02-01

Evidence of selection on splicing-associated loci in human populations and relevance to disease loci mapping

by Eric R. Gamazon, Anuar Konkashbaev, Eske M. Derks, Nancy J. Cox, Younghee Lee
Published 2017-07-01

Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma.

by Imge Hulur, Andrew D Skol, Eric R Gamazon, Nancy J Cox, Kenan Onel
Published 2017-01-01

An analysis of genetically regulated gene expression across multiple tissues implicates novel gene candidates in Alzheimer’s disease

by Zachary F. Gerring, Michelle K. Lupton, Daniel Edey, Eric R. Gamazon, Eske M. Derks
Published 2020-04-01

A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression.

by Zachary F Gerring, Eric R Gamazon, Eske M Derks, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
Published 2019-07-01

Multi-omic analysis elucidates the genetic basis of hydrocephalus

by Andrew T. Hale, Lisa Bastarache, Diego M. Morales, John C. Wellons, III, David D. Limbrick, Jr., Eric R. Gamazon
Published 2021-05-01

Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.

by Hae Kyung Im, Eric R Gamazon, Amy L Stark, R Stephanie Huang, Nancy J Cox, M Eileen Dolan
Published 2012-02-01

Exprtarget: an integrative approach to predicting human microRNA targets.

by Eric R Gamazon, Hae-Kyung Im, Shiwei Duan, Yves A Lussier, Nancy J Cox, M Eileen Dolan, Wei Zhang
Published 2010-10-01

Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans.

by Heather E Wheeler, Lidija K Gorsic, Marleen Welsh, Amy L Stark, Eric R Gamazon, Nancy J Cox, M Eileen Dolan
Published 2011-01-01

Variants affecting exon skipping contribute to complex traits.

by Younghee Lee, Eric R Gamazon, Ellen Rebman, Yeunsook Lee, Sanghyuk Lee, M Eileen Dolan, Nancy J Cox, Yves A Lussier
Published 2012-01-01

Campylobacter jejuni type VI secretion system: roles in adaptation to deoxycholic acid, host cell adherence, invasion, and in vivo colonization.

by Kvin Lertpiriyapong, Eric R Gamazon, Yan Feng, Danny S Park, Jassia Pang, Georgina Botka, Michelle E Graffam, Zhongming Ge, James G Fox
Published 2012-01-01

A transcriptome-wide association study of Alzheimer’s disease using prediction models of relevant tissues identifies novel candidate susceptibility genes

by Yanfa Sun, Jingjing Zhu, Dan Zhou, Saranya Canchi, Chong Wu, Nancy J. Cox, Robert A. Rissman, Eric R. Gamazon, Lang Wu
Published 2021-09-01

Contextualizing genetic risk score for disease screening and rare variant discovery

by Dan Zhou, Dongmei Yu, Jeremiah M. Scharf, Carol A. Mathews, Lauren McGrath, Edwin Cook, S. Hong Lee, Lea K. Davis, Eric R. Gamazon
Published 2021-07-01

Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record.

by Wei-Qi Wei, Lisa A Bastarache, Robert J Carroll, Joy E Marlo, Travis J Osterman, Eric R Gamazon, Nancy J Cox, Dan M Roden, Joshua C Denny
Published 2017-01-01

Cytotoxic and pathogenic properties of Klebsiella oxytoca isolated from laboratory animals.

by Alison Darby, Kvin Lertpiriyapong, Ujjal Sarkar, Uthpala Seneviratne, Danny S Park, Eric R Gamazon, Chara Batchelder, Cheryl Cheung, Ellen M Buckley, Nancy S Taylor, Zeli Shen, Steven R Tannenbaum, John S Wishnok, James G Fox
Published 2014-01-01

Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study

by Christi T Salisbury-Ruf, Clinton C Bertram, Aurelia Vergeade, Daniel S Lark, Qiong Shi, Marlene L Heberling, Niki L Fortune, G Donald Okoye, W Gray Jerome, Quinn S Wells, Josh Fessel, Javid Moslehi, Heidi Chen, L Jackson Roberts II, Olivier Boutaud, Eric R Gamazon, Sandra S Zinkel
Published 2018-10-01