NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation.

by Nadezhda Tikhmyanova, Erica A Golemis
Published 2011-01-01

Informatics-guided drug repurposing for Autosomal Dominant Polycystic Kidney Disease (ADPKD)

by Anna A. Kiseleva, Erica A. Golemis
Published 2020-02-01

Tumor-Targeted Drug Conjugates as an Emerging Novel Therapeutic Approach in Small Cell Lung Cancer (SCLC)

by Alexander Y. Deneka, Yanis Boumber, Tim Beck, Erica A. Golemis
Published 2019-09-01

Dcas supports cell polarization and cell-cell adhesion complexes in development.

by Nadezhda Tikhmyanova, Alexei V Tulin, Fabrice Roegiers, Erica A Golemis
Published 2010-08-01

Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model.

by Alexander Y Deneka, Leora Haber, Meghan C Kopp, Anna V Gaponova, Anna S Nikonova, Erica A Golemis
Published 2017-01-01

The centrosomal kinase Plk1 localizes to the transition zone of primary cilia and induces phosphorylation of nephrocystin-1.

by Tamina Seeger-Nukpezah, Max C Liebau, Katja Höpker, Tobias Lamkemeyer, Thomas Benzing, Erica A Golemis, Bernhard Schermer
Published 2012-01-01

A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer.

by Harsh B Pathak, Yan Zhou, Geetika Sethi, Jeff Hirst, Russell J Schilder, Erica A Golemis, Andrew K Godwin
Published 2015-01-01

Microscopy-Based Automated Live Cell Screening for Small Molecules That Affect Ciliation

by Peishan Zhang, Peishan Zhang, Anna A. Kiseleva, Anna A. Kiseleva, Vladislav Korobeynikov, Vladislav Korobeynikov, Hanqing Liu, Margret B. Einarson, Erica A. Golemis
Published 2019-02-01

Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer

by Alexander Y. Deneka, Margret B. Einarson, John Bennett, Anna S. Nikonova, Mohamed Elmekawy, Yan Zhou, Jong Woo Lee, Barbara A. Burtness, Erica A. Golemis
Published 2020-01-01

An improved method of delivering a sclerosing agent for the treatment of malignant pleural effusion

by Tim N. Beck, Alexander Y. Deneka, Louis Chai, Colin Kanach, Priya Johal, Nicolas J. Alvarez, Yanis Boumber, Erica A. Golemis, Glenn W. Laub
Published 2019-06-01

Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice.

by Zachary B Smithline, Anna S Nikonova, Harvey H Hensley, Kathy Q Cai, Brian L Egleston, David A Proia, Tamina Seeger-Nukpezah, Erica A Golemis
Published 2014-01-01

Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patients

by Ilya G. Serebriiskii, Caitlin Connelly, Garrett Frampton, Justin Newberg, Matthew Cooke, Vince Miller, Siraj Ali, Jeffrey S. Ross, Elizabeth Handorf, Sanjeevani Arora, Christopher Lieu, Erica A. Golemis, Joshua E. Meyer
Published 2019-08-01

Prevalence of pathogenic variants in DNA damage response and repair genes in patients undergoing cancer risk assessment and reporting a personal history of early-onset renal cancer

by Tiffiney R. Hartman, Elena V. Demidova, Randy W. Lesh, Lily Hoang, Marcy Richardson, Andrea Forman, Lisa Kessler, Virginia Speare, Erica A. Golemis, Michael J. Hall, Mary B. Daly, Sanjeevani Arora
Published 2020-08-01

NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis

by Suraj Peri, Evgeny Izumchenko, Adrian D. Schubert, Michael J. Slifker, Karen Ruth, Ilya G. Serebriiskii, Theresa Guo, Barbara A. Burtness, Ranee Mehra, Eric A. Ross, David Sidransky, Erica A. Golemis
Published 2017-11-01

Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR

by Linara Gabitova, Diana Restifo, Andrey Gorin, Kunal Manocha, Elizabeth Handorf, Dong-Hua Yang, Kathy Q. Cai, Andres J. Klein-Szanto, David Cunningham, Lisa E. Kratz, Gail E. Herman, Erica A. Golemis, Igor Astsaturov
Published 2015-09-01

Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence

by Janusz Franco-Barraza, Ralph Francescone, Tiffany Luong, Neelima Shah, Raj Madhani, Gil Cukierman, Essel Dulaimi, Karthik Devarajan, Brian L Egleston, Emmanuelle Nicolas, R Katherine Alpaugh, Ruchi Malik, Robert G Uzzo, John P Hoffman, Erica A Golemis, Edna Cukierman
Published 2017-01-01

Anti-Müllerian Hormone Signaling Regulates Epithelial Plasticity and Chemoresistance in Lung Cancer

by Tim N. Beck, Vladislav A. Korobeynikov, Alexander E. Kudinov, Rachel Georgopoulos, Nehal R. Solanki, Magda Andrews-Hoke, Timothy M. Kistner, David Pépin, Patricia K. Donahoe, Emmanuelle Nicolas, Margret B. Einarson, Yan Zhou, Yanis Boumber, David A. Proia, Ilya G. Serebriiskii, Erica A. Golemis
Published 2016-07-01

Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)

by Petr Makhov, Igor Bychkov, Bulat Faezov, Alexander Deneka, Alexander Kudinov, Emmanuelle Nicolas, Rohan Brebion, Eleanor Avril, Kathy Q. Cai, Leonid V. Kharin, Mark Voloshin, Elena Frantsiyants, Nikolay Karnaukhov, Oleg I. Kit, Iuliia Topchu, Rushaniya Fazliyeva, Anna S. Nikonova, Ilya G. Serebriiskii, Hossein Borghaei, Martin Edelman, Essel Dulaimi, Erica A. Golemis, Yanis Boumber
Published 2021-03-01