The Janus kinase 1/2 inhibitor baricitinib reduces biomarkers of joint destruction in moderate to severe rheumatoid arthritis

by Christian S. Thudium, Anne C. Bay-Jensen, Suntara Cahya, Ernst R. Dow, Morten A. Karsdal, Alisa E. Koch, Wenling Zhang, Robert J. Benschop
Published 2020-10-01

A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus.

by Yupeng Li, Richard E Higgs, Robert W Hoffman, Ernst R Dow, Xiong Liu, Michelle Petri, Daniel J Wallace, Thomas Dörner, Brian J Eastwood, Bradley B Miller, Yushi Liu
Published 2019-01-01

Baricitinib-associated changes in global gene expression during a 24-week phase II clinical systemic lupus erythematosus trial implicates a mechanism of action through multiple imm...

by Daniel J Wallace, Michelle A Petri, Thomas Dörner, Stephanie de Bono, Robert J Benschop, Ernst R Dow, Damiano Fantini, Richard E Higgs, Guilherme Rocha, Brenda Crowe, Nicole L Byers, Maria E Silk, Robert W Hoffman
Published 2020-12-01