A humanized CD3ε-knock-in mouse model for pre-clinical testing of anti-human CD3 therapy.

by Joel Crespo, Yi Ting Koh, Ningjie Hu, Paul A Moore, Ezio Bonvini, Andrew L Glasebrook, Andrea P Martin, Robert J Benschop
Published 2021-01-01

The Janus kinase 1/2 inhibitor baricitinib reduces biomarkers of joint destruction in moderate to severe rheumatoid arthritis

by Christian S. Thudium, Anne C. Bay-Jensen, Suntara Cahya, Ernst R. Dow, Morten A. Karsdal, Alisa E. Koch, Wenling Zhang, Robert J. Benschop
Published 2020-10-01

Interleukin-33 Contributes Toward Loss of Tolerance by Promoting B-Cell-Activating Factor of the Tumor-Necrosis-Factor Family (BAFF)-Dependent Autoantibody Production

by William A. Rose, Angela J. Okragly, Ningjie N. Hu, Montanea R. Daniels, Andrea P. Martin, Yi Ting Koh, Kristine Kikly, Robert J. Benschop
Published 2018-12-01

Glucose metabolic trapping in mouse arteries: nonradioactive assay of atherosclerotic plaque inflammation applicable to drug discovery.

by Richard G Conway, Eyassu Chernet, David C De Rosa, Robert J Benschop, Anne B Need, Emily C Collins, James S Bean, J Michael Kalbfleisch, Mark D Rekhter
Published 2012-01-01

Baricitinib-associated changes in global gene expression during a 24-week phase II clinical systemic lupus erythematosus trial implicates a mechanism of action through multiple imm...

by Daniel J Wallace, Michelle A Petri, Thomas Dörner, Stephanie de Bono, Robert J Benschop, Ernst R Dow, Damiano Fantini, Richard E Higgs, Guilherme Rocha, Brenda Crowe, Nicole L Byers, Maria E Silk, Robert W Hoffman
Published 2020-12-01