Discovery of Novel Druggable Sites on Zika Virus NS3 Helicase Using X-ray Crystallography-Based Fragment Screening

by Ali Munawar, Steven Beelen, Ahmad Munawar, Eveline Lescrinier, Sergei V. Strelkov
Published 2018-11-01

Propargylated Purine Deoxynucleosides: New Tools for Fluorescence Imaging Strategies

by Akkaladevi Venkatesham, Sambasiva Rao Pillalamarri, Flore De Wit, Eveline Lescrinier, Zeger Debyser, Arthur Van Aerschot
Published 2019-01-01

Functional and Molecular Characterization of the <i>Halomicrobium</i> sp. IBSBa Inulosucrase

by Gülbahar Abaramak, Jaime Ricardo Porras-Domínguez, Henry Christopher Janse van Rensburg, Eveline Lescrinier, Ebru Toksoy Öner, Onur Kırtel, Wim Van den Ende
Published 2021-04-01

Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish

by Yifan Zhang, Michiel Vanmeert, Aleksandra Siekierska, Annelii Ny, Jubi John, Geert Callewaert, Eveline Lescrinier, Wim Dehaen, Peter A. M. de Witte, Rafal M. Kaminski
Published 2017-08-01

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

by Baole Zhang, Luping Pang, Manesh Nautiyal, Steff De Graef, Bharat Gadakh, Eveline Lescrinier, Jef Rozenski, Sergei V. Strelkov, Stephen D. Weeks, Arthur Van Aerschot
Published 2020-10-01

A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics.

by Joleen Masschelein, Wesley Mattheus, Ling-Jie Gao, Pieter Moons, Rob Van Houdt, Birgit Uytterhoeven, Chris Lamberigts, Eveline Lescrinier, Jef Rozenski, Piet Herdewijn, Abram Aertsen, Chris Michiels, Rob Lavigne
Published 2013-01-01

Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

by Caroline M. Cremonez, Mohitosh Maiti, Steve Peigneur, Juliana Silva Cassoli, Alexandre A. A. Dutra, Etienne Waelkens, Eveline Lescrinier, Piet Herdewijn, Maria Elena de Lima, Adriano M. C. Pimenta, Eliane C. Arantes, Jan Tytgat
Published 2016-09-01

Molecular Dynamics Simulations in Drug Discovery and Pharmaceutical Development

by Outi M. H. Salo-Ahen, Ida Alanko, Rajendra Bhadane, Alexandre M. J. J. Bonvin, Rodrigo Vargas Honorato, Shakhawath Hossain, André H. Juffer, Aleksei Kabedev, Maija Lahtela-Kakkonen, Anders Støttrup Larsen, Eveline Lescrinier, Parthiban Marimuthu, Muhammad Usman Mirza, Ghulam Mustafa, Ariane Nunes-Alves, Tatu Pantsar, Atefeh Saadabadi, Kalaimathy Singaravelu, Michiel Vanmeert
Published 2021-12-01