Integrated Computational Approach for Virtual Hit Identification against Ebola Viral Proteins VP35 and VP40

by Muhammad Usman Mirza, Nazia Ikram
Published 2016-10-01

Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase

by Muhammad Usman Mirza, Matheus Froeyen
Published 2020-08-01

Mutagenesis of DsbAss is Crucial for the Signal Recognition Particle Mechanism in <i>Escherichia coli</i>: Insights from Molecular Dynamics Simulations

by Faiza Gul Durrani, Roquyya Gul, Muhammad Usman Mirza, Naheed Nazly Kaderbhai, Matheus Froeyen, Mahjabeen Saleem
Published 2019-04-01

Quantification of Berberine in <i>Berberis vulgaris</i> L. Root Extract and Its Curative and Prophylactic Role in Cisplatin-Induced In Vivo Toxicity and In Vitro Cytotoxicity

by Sarfraz Ahmad, Amina Hussain, Aroosha Hussain, Iskandar Abdullah, Muhammad Sajjad Ali, Matheus Froeyen, Muhammad Usman Mirza
Published 2019-06-01

Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches

by Mubarak A. Alamri, Muhammad Tahir ul Qamar, Muhammad Usman Mirza, Safar M. Alqahtani, Matheus Froeyen, Ling-Ling Chen
Published 2020-12-01

Inhibition of Oncogenic Kinases: An In Vitro Validated Computational Approach Identified Potential Multi-Target Anticancer Compounds

by Nazia Ikram, Muhammad Usman Mirza, Michiel Vanmeert, Matheus Froeyen, Outi M. H. Salo-Ahen, Muhammad Tahir, Aamer Qazi, Sarfraz Ahmad
Published 2019-03-01

Development of a Novel Multi-Epitope Vaccine Against Crimean-Congo Hemorrhagic Fever Virus: An Integrated Reverse Vaccinology, Vaccine Informatics and Biophysics Approach

by Muhammad Tahir Ul Qamar, Saba Ismail, Sajjad Ahmad, Muhammad Usman Mirza, Sumra Wajid Abbasi, Usman Ali Ashfaq, Ling-Ling Chen
Published 2021-06-01

Xanthogranulomatous Pyelonephritis: Synchronous Upper and Lower Gastrointestinal Bleed

by Muhammad Usman Mirza MBBS, John Van Taunay MD, Muhammad Waleed MBBS, Shiva Shankar Vangimalla MBBS, Sharana Hegde MBBS, Muhamad Alhaj Moustafa MD
Published 2019-04-01

Toxicity Evaluation of the Naphthalen-2-yl 3,5-Dinitrobenzoate: A Drug Candidate for Alzheimer Disease

by Fareeha Anwar, Fareeha Anwar, Uzma Saleem, Atta-Ur Rehman, Bashir Ahmad, Matheus Froeyen, Muhammad Usman Mirza, Lee Yean Kee, Iskandar Abdullah, Sarfraz Ahmad
Published 2021-05-01

Isolation of Antidiabetic Withanolides from <i>Withania coagulans</i> Dunal and Their In Vitro and <i>in silico</i> Validation

by Saima Maher, M. Iqbal Choudhary, Farooq Saleem, Saima Rasheed, Imran Waheed, Sobia Ahsan Halim, Muhammad Azeem, Iskandar Bin Abdullah, Matheus Froeyen, Muhammad Usman Mirza, Sarfraz Ahmad
Published 2020-07-01

Enhanced Thermostability and Enzymatic Activity of Cel6A Variants from <i>Thermobifida fusca </i>by Empirical Domain Engineering (Short Title: Domain Engineering of Cel6A)

by Imran Ali, Hafiz Muzzammel Rehman, Muhammad Usman Mirza, Muhammad Waheed Akhtar, Rehana Asghar, Muhammad Tariq, Rashid Ahmed, Fatima Tanveer, Hina Khalid, Huda Ahmed Alghamdi, Matheus Froeyen
Published 2020-08-01

Effect of Berberis vulgaris L. root extract on ifosfamide-induced in vivo toxicity and in vitro cytotoxicity

by Shazia Ilyas, Raheela Tabasum, Ali Iftikhar, Mamoona Nazir, Amina Hussain, Aroosha Hussain, Muhammad Sajjad Ali, Farooq Saleem, Uzma Saleem, Matheus Froeyen, Iskandar Abdullah, Muhammad Usman Mirza, Sarfraz Ahmad
Published 2021-01-01

A Putative Prophylactic Solution for COVID-19: Development of Novel Multiepitope Vaccine Candidate against SARS-COV-2 by Comprehensive Immunoinformatic and Molecular Modelling Appr...

by Hafiz Muzzammel Rehman, Muhammad Usman Mirza, Mian Azhar Ahmad, Mahjabeen Saleem, Matheus Froeyen, Sarfraz Ahmad, Roquyya Gul, Huda Ahmed Alghamdi, Muhammad Shahbaz Aslam, Muhammad Sajjad, Munir Ahmad Bhinder
Published 2020-09-01

Bioassay Directed Isolation, Biological Evaluation and in Silico Studies of New Isolates from <i>Pteris cretica</i> L.

by Farooq Saleem, Rashad Mehmood, Saima Mehar, Muhammad Tahir Javed Khan, Zaheer-ud-Din Khan, Muhammad Ashraf, Muhammad Sajjad Ali, Iskandar Abdullah, Matheus Froeyen, Muhammad Usman Mirza, Sarfraz Ahmad
Published 2019-07-01

Antigenic Peptide Prediction From E6 and E7 Oncoproteins of HPV Types 16 and 18 for Therapeutic Vaccine Design Using Immunoinformatics and MD Simulation Analysis

by Basit Jabbar, Shazia Rafique, Outi M. H. Salo-Ahen, Outi M. H. Salo-Ahen, Amjad Ali, Mobeen Munir, Muhammad Idrees, Muhammad Idrees, Muhammad Usman Mirza, Michiel Vanmeert, Syed Zawar Shah, Iqra Jabbar, Muhammad Adeel Rana
Published 2018-12-01

Molecular Dynamics Simulations in Drug Discovery and Pharmaceutical Development

by Outi M. H. Salo-Ahen, Ida Alanko, Rajendra Bhadane, Alexandre M. J. J. Bonvin, Rodrigo Vargas Honorato, Shakhawath Hossain, André H. Juffer, Aleksei Kabedev, Maija Lahtela-Kakkonen, Anders Støttrup Larsen, Eveline Lescrinier, Parthiban Marimuthu, Muhammad Usman Mirza, Ghulam Mustafa, Ariane Nunes-Alves, Tatu Pantsar, Atefeh Saadabadi, Kalaimathy Singaravelu, Michiel Vanmeert
Published 2021-12-01

Deleterious Variants in <i>WNT10A</i>, <i>EDAR,</i> and <i>EDA</i> Causing Isolated and Syndromic Tooth Agenesis: A Structural Perspective from Molecular Dynamics Simulations

by Asia Parveen, Sher Alam Khan, Muhammad Usman Mirza, Hina Bashir, Fatima Arshad, Maria Iqbal, Waseem Ahmad, Ahsan Wahab, Amal Fiaz, Sidra Naz, Fareeha Ashraf, Tayyaba Mobeen, Salman Aziz, Syed Shoaib Ahmed, Noor Muhammad, Nehal F. Hassib, Mostafa I. Mostafa, Nagwa E. Gaboon, Roquyya Gul, Saadullah Khan, Matheus Froeyen, Muhammad Shoaib, Naveed Wasif
Published 2019-10-01