Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase

by Muhammad Usman Mirza, Matheus Froeyen
Published 2020-08-01

Mutagenesis of DsbAss is Crucial for the Signal Recognition Particle Mechanism in <i>Escherichia coli</i>: Insights from Molecular Dynamics Simulations

by Faiza Gul Durrani, Roquyya Gul, Muhammad Usman Mirza, Naheed Nazly Kaderbhai, Matheus Froeyen, Mahjabeen Saleem
Published 2019-04-01

Quantification of Berberine in <i>Berberis vulgaris</i> L. Root Extract and Its Curative and Prophylactic Role in Cisplatin-Induced In Vivo Toxicity and In Vitro Cytotoxicity

by Sarfraz Ahmad, Amina Hussain, Aroosha Hussain, Iskandar Abdullah, Muhammad Sajjad Ali, Matheus Froeyen, Muhammad Usman Mirza
Published 2019-06-01

Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches

by Mubarak A. Alamri, Muhammad Tahir ul Qamar, Muhammad Usman Mirza, Safar M. Alqahtani, Matheus Froeyen, Ling-Ling Chen
Published 2020-12-01

Inhibition of Oncogenic Kinases: An In Vitro Validated Computational Approach Identified Potential Multi-Target Anticancer Compounds

by Nazia Ikram, Muhammad Usman Mirza, Michiel Vanmeert, Matheus Froeyen, Outi M. H. Salo-Ahen, Muhammad Tahir, Aamer Qazi, Sarfraz Ahmad
Published 2019-03-01

A novel pathogenic missense variant in CNNM4 underlying Jalili syndrome: Insights from molecular dynamics simulations

by Asia Parveen, Muhammad U. Mirza, Michiel Vanmeert, Javed Akhtar, Hina Bashir, Saadullah Khan, Saqib Shehzad, Matheus Froeyen, Wasim Ahmed, Muhammad Ansar, Naveed Wasif
Published 2019-09-01

Toxicity Evaluation of the Naphthalen-2-yl 3,5-Dinitrobenzoate: A Drug Candidate for Alzheimer Disease

by Fareeha Anwar, Fareeha Anwar, Uzma Saleem, Atta-Ur Rehman, Bashir Ahmad, Matheus Froeyen, Muhammad Usman Mirza, Lee Yean Kee, Iskandar Abdullah, Sarfraz Ahmad
Published 2021-05-01

Isolation of Antidiabetic Withanolides from <i>Withania coagulans</i> Dunal and Their In Vitro and <i>in silico</i> Validation

by Saima Maher, M. Iqbal Choudhary, Farooq Saleem, Saima Rasheed, Imran Waheed, Sobia Ahsan Halim, Muhammad Azeem, Iskandar Bin Abdullah, Matheus Froeyen, Muhammad Usman Mirza, Sarfraz Ahmad
Published 2020-07-01

Enhanced Thermostability and Enzymatic Activity of Cel6A Variants from <i>Thermobifida fusca </i>by Empirical Domain Engineering (Short Title: Domain Engineering of Cel6A)

by Imran Ali, Hafiz Muzzammel Rehman, Muhammad Usman Mirza, Muhammad Waheed Akhtar, Rehana Asghar, Muhammad Tariq, Rashid Ahmed, Fatima Tanveer, Hina Khalid, Huda Ahmed Alghamdi, Matheus Froeyen
Published 2020-08-01

Effect of Berberis vulgaris L. root extract on ifosfamide-induced in vivo toxicity and in vitro cytotoxicity

by Shazia Ilyas, Raheela Tabasum, Ali Iftikhar, Mamoona Nazir, Amina Hussain, Aroosha Hussain, Muhammad Sajjad Ali, Farooq Saleem, Uzma Saleem, Matheus Froeyen, Iskandar Abdullah, Muhammad Usman Mirza, Sarfraz Ahmad
Published 2021-01-01

A Putative Prophylactic Solution for COVID-19: Development of Novel Multiepitope Vaccine Candidate against SARS-COV-2 by Comprehensive Immunoinformatic and Molecular Modelling Appr...

by Hafiz Muzzammel Rehman, Muhammad Usman Mirza, Mian Azhar Ahmad, Mahjabeen Saleem, Matheus Froeyen, Sarfraz Ahmad, Roquyya Gul, Huda Ahmed Alghamdi, Muhammad Shahbaz Aslam, Muhammad Sajjad, Munir Ahmad Bhinder
Published 2020-09-01

Bioassay Directed Isolation, Biological Evaluation and in Silico Studies of New Isolates from <i>Pteris cretica</i> L.

by Farooq Saleem, Rashad Mehmood, Saima Mehar, Muhammad Tahir Javed Khan, Zaheer-ud-Din Khan, Muhammad Ashraf, Muhammad Sajjad Ali, Iskandar Abdullah, Matheus Froeyen, Muhammad Usman Mirza, Sarfraz Ahmad
Published 2019-07-01

Deleterious Variants in <i>WNT10A</i>, <i>EDAR,</i> and <i>EDA</i> Causing Isolated and Syndromic Tooth Agenesis: A Structural Perspective from Molecular Dynamics Simulations

by Asia Parveen, Sher Alam Khan, Muhammad Usman Mirza, Hina Bashir, Fatima Arshad, Maria Iqbal, Waseem Ahmad, Ahsan Wahab, Amal Fiaz, Sidra Naz, Fareeha Ashraf, Tayyaba Mobeen, Salman Aziz, Syed Shoaib Ahmed, Noor Muhammad, Nehal F. Hassib, Mostafa I. Mostafa, Nagwa E. Gaboon, Roquyya Gul, Saadullah Khan, Matheus Froeyen, Muhammad Shoaib, Naveed Wasif
Published 2019-10-01